Primary Immunodeficiency Diseases Network (PIDNet)
Objective
The principal objectives of the UPIN are: 1- To increase awareness of PID among physician 2- To support exchange between centers for clinical education 3- To develop consensus statements and clinical guidelines for diagnosis and therapy of PID
Definition
Primary immunodeficiency diseases (PIDs) consist of a group of genetic disorders that predispose the patients to severe, sometimes life-threatening, infections. Many patients with PI are undiagnosed. Lack of awareness on PIDs in physicians is one of the major reasons in late diagnosis and the delay in adequate treatment deteriorating patients' morbidity and mortality. Better understanding of the immune system and will continue to improve quality of life for those with PIDs UPIN was established to increase awareness of PID among physician and also to support exchange between centers for clinical education.
Group members
Founder
Managing Director
Member
Congress
- 8th International Conference on Immunodeficiency Diseases (April 23-24, 2016)
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- 9th International Congress on Immunodeficiency Diseases (April 21-22, 2017)
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Paper
- Azizi G, Rezaei N, Kiaee F, Tavakolinia N, Yazdani R, Mirshafiey A, Aghamohammadi A. T-Cell Abnormalities in Common Variable Immunodeficiency. J Investig Allergol Clin Immunol. 2016;26(4):233-43.
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- Azizi G, Abolhassani H, Asgardoon MH, Alinia T, Yazdani R, Mohammadi J, Rezaei N, Ochs HD, Aghamohammadi A. Autoimmunity in common variable immunodeficiency: epidemiology, pathophysiology and management. Expert Rev Clin Immunol. 2017 Feb;13(2):101-11...
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- Ziaee V, Maddah M, Moradinejad MH, Rezaei A, Zoghi S, Sadr M, Harsini S, Rezaei N. Association of interleukin-6 single nucleotide polymorphisms with juvenile idiopathic arthritis. Clin Rheumatol. 2017 Jan;36(1):77-81.
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- Yazdani R, Ganjalikhani-Hakemi M, Esmaeili M, Abolhassani H, Vaeli S, Rezaei A, Sharifi Z, Azizi G, Rezaei N, Aghamohammadi A. Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency. Clin Immunol. 2017 Feb;175:124-1...
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- Fazel A, Kashef S, Aleyasin S, Harsini S, Karamizadeh Z, Zoghi S, Flores SK, Boztug K, Rezaei N. Novel AICDA mutation in a case of autosomal recessive hyper-IgM syndrome, growth hormone deficiency and autoimmunity. Allergol Immunopathol (Madr). 2017...
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- Namazi S, Tajik N, Ziaee V, Sadr M, Soltani S, Rezaei A, Zoghi S, Rezaei N. APRIL gene polymorphism and serum sAPRIL levels in children with systemic lupus erythematosus. Clin Rheumatol. 2017 Apr;36(4):831-836.
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- Mohammadzadeh I, Moazzami B, Ghaffari J, Aghamohammadi A, Rezaei N. Primary immunodeficiency diseases in Northern Iran. Allergol Immunopathol (Madr). 2017 May - Jun;45(3):244-250.
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- Azizi G, Hafezi N, Mohammadi H, Yazdani R, Alinia T, Tavakol M, Aghamohammadi A, Mirshafiey A. Abnormality of regulatory T cells in common variable immunodeficiency. Cell Immunol. 2017 May;315:11-17.
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- Aghamohammadi A, Abolhassani H, Puchalka J, Greif-Kohistani N, Zoghi S, Klein C, Rezaei N. Preference of Genetic Diagnosis of CXCR4 Mutation Compared with Clinical Diagnosis of WHIM Syndrome. J Clin Immunol. 2017 Apr;37(3):282-286.
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- Gholami K, Laali E, Abolhassani H, Ahmadvand A, Mohebbi N, Javadi MR, Aghamohammadi A, Rezaei N. Costs of Hospital Admission on Primary Immunodeficiency Diseases. Iran J Public Health. 2017 Mar;46(3):342-350.
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- Azizi G, Abolhassani H, Mahdaviani SA, Chavoshzadeh Z, Eshghi P, Yazdani R, Kiaee F, Shaghaghi M, Mohammadi J, Rezaei N, Hammarström L, Aghamohammadi A. Clinical, immunologic, molecular analyses and outcomes of iranian patients with LRBA deficiency:...
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- Sepehri F, Langarizadeh M, Sharifi L, Azizi G, Safdari R, Aghamohammadi A. Developing Inference Model to Diagnosis of Primary Immunodeficiency Diseases in Protégé. Acta Med Iran. 2017 Apr;55(4):280-281.
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- Sharifi L, Mohsenzadegan M, Aghamohammadi A, Rezaei N, Tofighi Zavareh F, Bokaie S, Moshiri M, Azizi G, Mirshafiey A, Aghazadeh Z. Immunomodulatory effect of G2013 (a-L-Guluronic acid) on theTLR2 and TLR4 in human mononuclear cells. Curr Drug Discov...
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- Farrokhi S, Shabani M, Aryan Z, Zoghi S, Krolo A, Boztug K, Rezaei N. MHC class II deficiency: Report of a novel mutation and special review. Allergol Immunopathol (Madr). 2017 Jul 1. pii: S0301-0546(17)30077-0. doi: 10.1016/j.aller.2017.04.006.
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- Azizi G, Abolhassani H, Kiaee F, Tavakolinia N, Rafiemanesh H, Yazdani R, Mahdaviani SA, Mohammadikhajehdehi S, Tavakol M, Ziaee V, Negahdari B, Mohammadi J, Mirshafiey A, Aghamohammadi A. Autoimmunity and its association with regulatory T cells and...
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- Azizi G, Abolhassani H, Yazdani R, Mohammadikhajehdehi S, Parvaneh N, Negahdari B, Mohammadi J, Aghamohammadi A. New therapeutic approach by sirolimus for enteropathy treatment in patients with LRBA deficiency. Eur Ann Allergy Clin Immunol. 2017 Sep;...
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- Abolhassani H, Chou J, Bainter W, et al. Clinical, immunologic, and genetic spectrum of 696 patients with combined immunodeficiency. J Allergy Clin Immunol. 2017 Sep 12. pii: S0091-6749(17)31436-7.
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- Azizi G, Tavakol M, Rafiemanesh H, Kiaee F, Yazdani R, Heydari A, Abouhamzeh K, Anvari P, Mohammadikhajehdehi S, Sharifia L, Bagheri Y, Mohammadi H, Abolhassani H, Aghamohammadi A. Autoimmunity in a cohort of 471 patients with primary antibody defici...
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- Zaki-Dizaji M, Akrami SM, Abolhassani H, Rezaei N, Aghamohammadi A. Ataxia telangiectasia syndrome: moonlighting ATM. Expert Rev Clin Immunol. 2017 Dec;13(12):1155-1172.
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- Azizi G, Mirshafiey A, Abolhassani H, Yazdani R, Ansariha FJ, Shaghaghi M, Mortazavi-Jahromi SS, Noorbakhsh F, Rezaei N, Aghamohammadi A. The circulating T helper subsets and regulatory T cells in patients with common variable immunodeficiency with n...
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