Banafshe Abadi

Name: Banafshe

Last Name: Abadi

Education          

Sep 2015 - Jan 2022   Kerman University of Medical Sciences

PharmD

GPA: 3.7 out of 4, 2nd rank out of 80 pharmacy students at Kerman University of Medical Sciences.

Thesis: Synthesis and characterization of sialic acid coated selenium nanoparticles with appropriate size and determination of hemolytic activity and cytotoxicity of synthesized nanoparticles on human glioblastoma cell line, T98. (Under the supervision of Prof. Hamid Frootanfar and Prof. Payam Khazaeil).          

Research Positions         

May 2024-Present                         Graduate Research Assistant

Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Kerman University of Medical Sciences.

May 2022- May 2024                    Graduate Research Assistant

Herbal and Traditional Medicines Research Center, Kerman University of Medical Sciences.

Nov 2023-Dec 2023                       Graduate Teaching Assistant

Medicinal Chemistry Department, Faculty of Pharmacy, Kerman University of Medical Sciences.

Mar 2019-Dec 2020        Under Graduate Research Assistant

Pharmaceutical Sciences and Cosmetic Products Research Center, Kerman University of Medical Sciences. 

Research Grants/Fundings

       Active

•            NIMAD (National Institute for Medical Research and Development), Ministry of Health and Medical Education, Iran (PI: Banafshe Abadi/Mojtaba Shakibaei) Approval ID: IR.NIMAD.REC.1402.035.

Preparation, characterization, and evaluation of the neuroprotective activity of chitosan-selenium nanoparticles containing quercetin: in vitro study.

Publications

Research Paper

1.           Banafshe Abadi, Payam Khazaeli, Hamid Forootanfar, Mehdi Ranjbar, Meysam Ahmadi-Zeidabadi, Ali Nokhodchi, Atefeh Ameri, Mahboubeh Adeli-Sardou, Maryam Amirinejad. Chitosan-sialic acid nanoparticles of selenium: Statistical optimization of production, characterization, and assessment of cytotoxic effects against two human glioblastoma cell lines. International Journal of Pharmaceutics, 2023 April 25; https://doi.org/10.1016/j.ijpharm.2023.122884 

2.           Banafshe Abadi, Jahangir Abdesheikhi, Farnaz Sedgy, Merat Mahmoodi, Hossein Fallah. Silibinin improved the function of T cells in peripheral blood mononuclear cells (PBMCs) co-cultured with U-87 MG cell line. Avicenna Journal of Phytomedicine. 2023 August 31; 10.22038/AJP.2023.22935 

3.           Nazanin Sabet, Banafsheh Abadi, Amirhossein Moslemizadeh, Mohammadamin Rajizadeh, Fatemeh Arabzadehe, Seyyed Sajjad Vakili Shahrbabaki, Zahra Soltani, Forouzan Rafie, Hamideh Bashiri. The effect of mild- and moderate-intensity interval training on cognitive behaviors of male and female rats with VPA-induced autism. Heliyon, 2023 October 5; https://doi.org/10.1016/j.heliyon.2023.e20641

4.           Banafshe Abadi, Fatemeh Askarian, Neda Mohammadi, Behzad Behnam. Biocompatible fluorescent carbon quantum dots from cumin seeds: preparation, characterization and in vitro biocompatibility tests, Journal of Cluster Science: 1521–1531 (2024). https://doi.org/10.1007/s10876-024-02609-w 

Review Paper

1.           Banafshe Abadi, Niloufar Yazdanpanah, Ali Nokhodchi, Nima Rezaei. Smart Biomaterials to Enhance the Efficiency of Immunotherapy in Glioblastoma: State of the Art and Future Perspectives. Advanced Drug Delivery Reviews. 2021 Nov 2:114035. https://doi.org/10.1016/j.addr.2021.114035 

2.           Mohammed Bhia, Mahzad Motallebi, Banafshe Abadi, Atefeh Zarepour, Miguel Pereira-Silva, Farinaz Saremnejad, Ana Cláudia Santos, Ali Zarrabi, Ana Melero, Seid Mahdi Jafari, Mehdi Shakibaei. Naringenin nano-delivery systems and their therapeutic applications. Pharmaceutics: 2021; 13 (2): 291. https://doi.org/10.3390/pharmaceutics13020291

3.           Mahshid Moballegh Nasery, Banafshe Abadi, Delaram Poormoghadam, Ali Zarrabi, Peyman Keyhanvar Hashem Khanbabaei, Milad Ashrafizadeh, Reza Mohammadinejad, Shima Tavakol, Gautam Sethi. Curcumin Delivery Mediated by Bio-Based Nanoparticles: A Review. Molecules: 2020; 3 (25): 689-720. https://doi.org/10.3390/molecules25030689 

4.           Banafshe Abadi, Jaleh Tahsili, Saman Bolourian, Nazanin Goshtasbi, Mahboubeh Adeli-Sardou, Hamid Forootanfar. Electrospun Hybrid Nanofibers: Fabrication, Characterization, and Biomedical Applications. Frontiers in Bioengineering and Biotechnology:2235. 10.3389/fbioe.2022.986975

5.           Banafshe Abadi, Shamim Hosseinalipour, Sanaz Nikzad, Sara Pourshaikhali, Hadis Fatahalipour, Golnaz Shafiei, Mahboubeh Adeli-Sardou, Mojtaba Shakibaie, Hamid Forootanfar. Capping Agents for Selenium Nanoparticles in Biomedical Applications. Journal of cluster sciences: 2022: 1-22. 

6.           Banafshe Abadi, Yasamin Shahsavani, Mahsa Faramarzpour, Nima Rezaei, Hamid‐Reza Rahimi. Antidepressants with anti‐tumor potential in treating glioblastoma: A narrative review. Fundamental & Clinical Pharmacology: 2021. https://doi.org/10.1111/fcp.12712 

7.           Banafshe Abadi, Meysam Ahmadi-Zeidabadi, Luciana Dini, Cristian Vergallo. Current Status and Challenges of Stem Cell-based Therapy for the Treatment of Glioblastoma Multiforme. Hematology/Oncology and Stem Cell Therapy: 2020; 14(1). https://doi.org/10.1016/j.hemonc.2020.08.001

8.           Ali Karimi Sisakht, Mohammad Malekan, Farbod Ghobadinezhad, Seyedeh Negar Mousavi Firouzabadi, Ameneh Jafari, Seyed Mohammad Ali Mirazimi, Banafshe Abadi, Rana Shafabakhsh, Hamed Mirzaei. Cellular Conversations in Glioblastoma Progression, Diagnosis and Treatment. Cellular and molecular neurobiology: 2022: 1-19. https://doi.org/10.1007/s10571-022-01212-9

9.           Banafshe Abadi, Mehran Ilaghi, Yasamin Shahsavani, Mahsa Faramarzpour, Mohammad Bagher Oghazian, Hamid-Reza Rahimi. Antibiotics with Antiviral and Anti-Inflammatory Potential Against Covid-19: A Review. Current Reviews in Clinical and Experimental Pharmacology: 2021. 10.2174/2772432817666220106162013

10.         Banafshe Abadi, Amir Hossein Aarabi Jeshvaghani, Hadis Fathalipour, Leili Dehghan,Kosar Rahimi Sirjani,Hamid Forootanfar. Therapeutic strategies for COVID-19: From Bench to Bedside. Iranian Journal of Medical sciences:2022. 10.30476/IJMS.2021.92662.2396

11.         Alireza Sarkar Lotf-abadi, Banafshe Abadi, Nima Rezaei. Biomimetic Nanotechnology for Cancer Immunotherapy: State of the Art and Future Perspective. International Journal of Pharmaceutics:2024.https://doi.org/10.1016/j.ijpharm.2024.123923

Book Chapter

1.           Banafshe Abadi, Nima Rezaei. (2023). Introduction on Personalized Immune-Oncology. In: Rezaei, N. (eds) Handbook of Cancer and Immunology. Springer, Cham. https://doi.org/10.1007/978-3-030-80962-1_286-1

2.           Mahshid Moballegh Nasery, Banafshe Abadi, Nasrin Seyedpour, Parsa Bazdar, Touba Eslaminejad. “Chapter 5 - Smart bio-encapsulation for immunotherapy”. In Micro and Nano Technologies, Smart Nanomaterials for Bioencapsulation, edited by Guillermo Castro, Ashok Nadda, Tuan Nguyen, Swati Sharma, Ram Gupta, Elsevier: 2022: 75-90. https://doi.org/10.1016/B978-0-323-91229-7.00009-X.

3.           Kiarash Saleki, Mohammad Banazadeh, Banafshe Abadi, Zeynab Pirmoradi, Zahra Esmaili, Shiva Amiri, Ramtin Pourahmad, Kristi A Kohlmeier, Mohammad Shabani. "Astrocytic Abnormalities in Schizophrenia". Neurophysiology - Networks, Plasticity, Pathophysiology, and Behaviour, edited by Thomas Heinbockel, IntechOpen, 2022. 10.5772/intechopen.106618

Invited Journal Review  

•            Pharmacological Research (Elsevier).

•            Heliyon (Elsevier).          

Awards & Honors           

2023                    Distinguished National Researcher, issued by the Ministry of Health and Medical Education, Iran.

2022                    Distinguished researcher among medical, dentistry, and pharmacy students

 in Kerman province, issued by Kerman Governorate, Kerman, Iran.

2022                    Distinguished researcher at Kerman University of Medical Sciences, issued by Kerman University of   Medical Sciences, Kerman, Iran.

2020                    1st team in the third National Stem Cell and Regenerative Medicine Startup Weekend event, issued by Vice President Scientific Technology and Knowledge Council for Development of Regenerative Medicine and Stem Cell Technologies, Iran.

2018                    Award and appreciation letter for the 10th National Olympiad of Medical Sciences Students in the field of basic sciences, issued by the Ministry of Health and Medical Education, Iran.

2018                    6th team in the 10th National Olympiad of Medical Sciences Students in the field of basic sciences, issued by the Ministry of Health and Medical Education, Iran.

Skills

Technical Skills 

•            Nanomaterials fabrication (micelle, metal-polymer nanocomposites, Nanofiber, carbon quantum dot).         

•            Nanomaterials characterization (FTIR, UV-Vis, XRD).

•            Analytical techniques (UV-vis, HPLC, AAS, Fluro-spectrophotometer).

•            Cellular tests (Hemolysis assay, MTT assay, MIC determination).

•            Antioxidant activity assays (DPPH assay, FRAP assay).      

•            Eukaryotic cell culture (3T3, T98, U87, A172, PC12 cell lines) (Intermediate).

•            Prokaryotic cell culture (S. aureus, S. epidermidis, P. aeruginosa).

•            In vitro release study (Franz cell).

•            Behavioral animal studies (open field test, Three-chamber sociability test, Moris water maze,

 Elevated plus maze) (Intermediate).

Software

•            Optimization (Design-Expert).

•            Statistical analysis (GraphPad-Prism).

•            Programming (Python, R) (Intermediate).

•            Protein Modeling / Docking (AlphaFold 2, Auto Duck tool, Auto Duck vina) (Intermediate).          

Executive experiences

2021-present       Research mentor in USERN Research Internship

2020-Present     Founder & Managing director of Brain Cancer Research Core (BCRC) interest group

at Universal Scientific Education and Research Network (USERN).

2020 - 2022        President of Iranian Pharmacy Students Association (IPhSA) at Kerman local.

2016-2021          Head of cancer committee of the Research Education Scientific Association (RESA) at Kerman University of Medical Sciences.

May - April 2021              Executive manager of the first national online Interprofessional Clinical Case Based Competition (ICC) held at Kerman University of Medical Sciences.

Academic memberships

2020-Present     Member of the Medical Council of Iran.

2021 - Present   Member of Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN).

2019 - 2021       

Member of the central council of Student Medical Sciences Education Development Committee.

2017 - 2018        Member of the central council of the Student Research Committee.

Attended workshops

Feb 2021             "Journal Selection, Submission, and Peer Reviewing of Assignments", USERN.

Feb 2021             "Editing Book with International Publishers", USERN.

Feb 2021             "Systematic Review", USERN.

Feb 2021             "Scientific Writing", USERN.

2021      "Python programming course”, Amanj Academy.

April 2020           "Online course under the subject of biotechnology", Surena Academy.

June 2020           "Market Research in the Healthcare industry", Surena Academy.

Jul - Aug 2020    "Pharmaceutical Biotechnology Industry Course", Cinnagen company.

Jan - Feb 2016                  "Wet Lab Techniques winter school", Pasteur Institute of Iran.

Nov 2016            "Manufacturing Methods and Synthesis of Nanomaterials", Pasteur Institute of Iran.