mojtaba Hedayati Ch


-   Identity Information




-          Name: Mojtaba Hedayati Chakosari, Assistant professor of microbial toxins and medical microbiology. Guilan University of Medical Sciences, Medical School, Microbiology Department, Rasht, Guilan, Iran.


-          Address: Zip Code 4188783417, Karimi Alley, Pamchal, Imam Khomeini St., Rasht, Guilan, Iran


-          Phone number: 00989113386640


-          Email:
[email protected]


-          Date of Birth:18 Jan 1984


-          Marital status:
Married


-          Children status:
One child


-          Military service status:
Conscription-exempt


______________________________________________________________________________



-   Education


-          Bachelors degree of Biology, Razi University of Kermanshah, 2002.


-          Master of Science in Microbiology, Islamic Azad University of Lahijan (Thesis at Pasteur institute of Iran), 2007.


-          Microbial Toxins, Baqiyatallah University of Medical Sciences, Ph.D., 31 Dec 2018.


Ph.D. thesis title: Isolation of ssDNA aptamer against
Staphylococcus aureus enterotoxin B (SEB) to design ELASA measurement and quantitative measurement of SEB in artificially contaminated human serum.



Sabbatical Leave


-          Sabbatical leave
by the Pasteur Institute of Iran for England, London Natural History Museum, 2010.


(Dr. paul Ready, London School of Hygiene and Tropical Medicine, Keppel Street London, United Kingdom).


-   Academic Employment and Other



-   Pasteur Institute of Iran (Department of Biotechnology, Malaria Research Group, National Iranian Insectarium,
in charge of Microbiology Laboratory) (2011)


-    Pasteur Institute of Iran (Systematic Molecular Lab, Department of Parasitology) (2010).


-   A Faculty ofMicrobiology, Parasitology and Immunology Department of Guilan University of Medical Sciences (Since 2016).


-   Director of Food and Drug Control Laboratory,
Vice chancellor for food and drug, Guilan University of Medical Sciences (2019).


-   Kharazmi Pharmaceutical Company, Biological and Anticancer Products Co., Research & Development Dep., Specialty Field: Anticancer Drugs (2015).


-   Darou Pakhsh Pharmaceutical Company, Presidency of Biotechnology Laboratory and Production of Recombinant Drugs (2016).



-   Teaching and Research Experience



-Teaching


-          Teaching theoretical and practical Full-time medical microbiology courses at Guilan University of Medical Sciences (Faculties of Medicine, Dentistry, Pharmacy, Nursing and Midwifery, Laboratory and Health Sciences in Rasht, Anzali and Langrood, Iran). Supervisor of 5 Master’s Thesis. Advisor of 5 Master’s Thesis from May 2016 to Feb 2020, Rasht, Guilan, Iran.


-          Organizer and Academic Secretary of the First Winter School of Student Research Committee, Guilan University of Medical Sciences, Rasht, Iran.



-Fields of Research and interest:


- Applied and therapeutic usage of microbial toxins


- Toxin producing microorganisms (Pathogens, Environment, Microbiota).


- Tropical and Neurodegenerative diseases/ Cancer.


-Research Experiences



  • Mastery of basic and advanced bacteriology laboratory techniques (environmental isolation and clinical sampling, culture, biochemical and molecular identification of microorganisms, QC and QA and GMP and standard microbiology laboratory accreditation)
  • Antibiogram tests, MIC, MBC.
  •  Antimicrobial nanoparticles
  •  Cloning and Purification of primary and secondary microbial metabolites such as microbial toxins (Bacterial endotoxins and exotoxins like clostridial neurotoxins and staphylococcal enterotoxins).
  • Gene-Protein docking
  • Bioinformatic
  • Gene expression and protein purification
  • Bacterial genetic polymorphism, DNA barcoding and Phylogenetic.
  • In-silico, in-vitro gene and protein manipulation
  • Co-operation in making anticancer drugs by using microbial products
  • Recombinant drugs
  • Design of probes and primers
  • Genomic analysis
  • Design and construction of therapeutic Aptamers and aptamer isolation by SELEX
  • DNA extraction in different ways from reservoirs and carriers of the disease and clinical specimens
  • Cloning
  • Electrophoresis 
  • PCR
  • Competent bacteria
  • Microscopic identification of microorganisms  
  • Molecular identification of the bacteria and the parasites
  • Relative familiarity with the study of genetic diversity and polymorphism in different genera and species of bacteria and parasites (Phylogenetic-Blast and other relates)
  • Performing specialized field study for nosocomial bacterial isolation. Performing specialized field operations of malaria and leishmaniasis for different vectors and reservoirs collection (Arthropods, Insects, Mammals, reptiles …).
  • Clinical sampling fields in rural and urban area and preparing slides, culture and biopsy.
  • Working with laboratory and wild animals and wild insects (injection, rat and mice stereotaxic surgery and insect dissection).
  • Chromatography
  • Aptasensors
  • Recombinant pharmaceutical products
  • ELISA
  • SPR
  • Design molecular diagnostic rapid tests



  • Publications


-          Books


-          Persian translation of Antibiotic resistant bacteria, Pasteur Institute of Iran, Daneshmand Publication, Tehran, Iran, 2009.



-          Persian translation of
Jawetz Microbiology 2013, Arjmand Publication, Tehran, Iran, 2013.




v Highlight Articles



-          Nanoniosome-encapsulated tobramycin enhanced antibacterial activity against multidrug- resistant clinical strains of
Pseudomonas aeruginosa



Mojtaba Hedayati Ch,
ArefehAbolhassaniTarghi
, Fatemeh Heidari,ZahraSalehiMoghadam,
Amir Mirzaie, Shohreh
Zare Karizi, Maryam Moghtaderi
, Iman Akbarzadeh.


 J Biomed Mater Res. 2020;1–15 (DOI: 10.1002/jbm.a.37086).



-          Enriched environment effect on lipopolysaccharide-induced spatial learning,memory impairment and hippocampal inflammatory cytokine levels in male rats


Arman Keymoradzadeh, Mojtaba Hedayati Ch, Mahmood Abedinzade,Rohollah Gazor, Mohammad Rostampour, Behrooz Khakpour Taleghani


Behavioural Brain Research, 2020, 394, 112814 (DOI: 10.1016/j.bbr.2020.112814).



-          Tympanosclerosis and Atherosclerosis Plaques: A Comparative Analytical Study on some new Microbiological and Immunohistochemical Aspects (Accepted, Oct 2020)


Shadman Nemati" [email protected], "Alia Saberi" [email protected], "Ali Faghih Habibi" [email protected], "Hossein Hemmati" [email protected], "Reza Jafari-Shakib" [email protected], "Mojtaba Hedayati Ch" [email protected]


European Archives of Oto-Rhino-Laryngology, Ref.: 
Ms. No. EAOR-D-20-02323R1



-          Diphtheria toxoid nanoparticles improve learning and memory impairment, in an animal model of Alzheimer’s disease 


Samane Heydari, Mojtaba Hedayati Ch, Mahmood Abedinzade, Iraj Nikokar, Ehsan Aboutaleb, Abolfazl Khafri, Ali Rezaei Mokarram


pharmacology reports, 2019 (DOI: 10.1007/s43440-019-00017-w).



-          Antibacterial, anti-biofilm and anti -quorum sensing activities of phyto-synthesized silver nanoparticles against Klebsiella pneumoniae strains"


Fatemeh Foroohimanjili, Amir Mirzaie, Seyed Mohammad Mehdi Hamdi1, Hassan Noorbazargan,
Mojtaba Hedayati Ch, Aghigh Dolatabadi, Hossein Rezaie, Faezeh Mohammadpour Bishak


Journal of basic microbiology, Publishing company, Article ID: JOBM2408, 2019,
Journal of Basic Microbiology. 2020;1–15,
(DOI: 10.1002/jobm.201900511)
.




-          Biogenic synthesis of AgNPs using Artemisia oliveriana extract and their biological activities for an effective treatment of lung cancer


Nafiseh Nafisi Fard, Hassan Noorbazargan,
Amir Mirzaie, Mojtaba Hedayati Ch, Zeinab moghimiyan,
Arian Rahimi


Artificial Cells, Blood Substitutes, and Biotechnology: An International Journal, 2018, (DOI:
10.1080/21691401.2018.1528983).



-          Isolation of a new ssDNA aptamer against staphylococcal enterotoxin B based on CNBr‐activated sepharose‐4B affinity chromatography


Mojtaba Hedayati Ch, Jafar Amania, Hamid Sedighiana, Mohsen Aminb, Jafar Salimianc, Raheleh Halabiana and Abbas Ali Imani Fooladi


Journal of Molecular recognition, 2016, (DOI: 10.1002/jmr.2542).


-          Aptamer-based Targeted Delivery of miRNA let-7d to
Gastric Cancer Cells as a Novel Anti-Tumor Therapeutic Agent


Puyan Daei, Mahsa Ramezanpour, Korosh Khanaki, Maryam Tabarzad, Iraj Nikokar,
Mojtaba Hedayati Ch, Ali Elmi.


Iranian Journal of Pharmaceutical Research, Manuscript ID: IJPR-12243, July 27, 2018.


-          Development and stability comparison of targeted therapeutic nanomolecules of aptamer-miRNA conjugates using two methods of conjugation


M Ramezanpour, P Daei, K Khanaki, Mojtaba Hedayati Ch, M Tabarzad


International Pharmacy Acta 1 (1), 86-86, 2018.




  • Other Articles

-          Applying Bioinformatic Tools for Modeling and Modifying Type II E. Coli l-Asparginase to Present a Better Therapeutic Agent/Drug for Acute Lymphoblastic Leukemia


Mahdieh Mahboobi, Hamid Sedighian, Mojtaba Hedayati Ch, Bijan Bambai, Saeed EsmaeilSoofian, and Jafar Amani.


Int J Cancer Manag. In Press (In Press):e5785, Int J Cancer Manag. In Press(In Press):e5785, 2017 March 20.


-          Applications and modifications of aptamers: potential tool for medical microbiology


Abbas Ali Imani Fooladi, Mojtaba Hedayati Ch, Mohsen Amin, Jafar Amani


Reviews in Medical Microbiology, 27:107–120, 2016.


-          Molecular epidemiology of ESBL-producing Klebsiella pneumoniae isolates in intensive care units of a tertiary care hospital, North of Iran


Fatemeh Ghaffarian, Mojtaba Hedayati, Hadi Sedigh Ebrahim-Saraie, Zahra Atrkar Roushan, Ali Mojtahedi


  Cellular and molecular biology Vol 64, No 7, 2018.


-          Distribution of high-level mupirocin resistance among clinical MRSA


H Mahmoodzadeh Hosseini, N kiyani, M Amin, M Hedayati Ch,


Journal of Chemotherapy, 2016, 1-5, (DOI: 10.1080/1120009X.2016.1201257).


Molecular Screening of Staphylococcal Enterotoxin Type P Encoding Gene from Clinical Isolates


RA Ataee, M Hedaiatich, RM Khanshan, M Hosein, Jundishapur Journal of Microbiology, 2013.


-          The Prevalence of Rectovaginal Colonization and Antibiotic Susceptibility Pattern of Streptococcus agalactiae in Pregnant Women in Al-Zahra Hospital, Rasht, Iran


S Sahraee, F Milani, ZA Roushan, MH Ch, S Rostami, S Shoja, R Sheikhi


Infectious Diseases in Clinical Practice 2019, 27 (3), 143-147.




-          Highlights About Recent Sepsis Related Studies


Badlou, B. A. & Hedayati Ch, M


2020; CPQ Medicine, 8(4), 01-03.




-          Combination of Calcium Channels Inhibitors Prevents LPS – Induced (pro-)Inflammatory Release of the TNF-a and IL-1ß,
In Vivo


Hedayati Ch M, Abedinzade M, Golshekan M and Badlou BA


EC Cardiology 7.3 (2020): 01-09.


-          COVID-19 War, Human Microbiota Function


Hedayati Ch, M & Badlou, B. A.


Journal of internal medicine and emergency research, 2020, 1 (2): 1-4.


-          COVID 19 War, Triangle with inflammation and infection


Hedayati Ch, M & Badlou, B. A.


Haematology International Journal, ISSN:2578-501X, 2020, 4 (2), DOI: 10.23880/jij-16000161.



-          COVID-19 War, Cytokines storms Enigma


Bahram Alamdary Badlou & Mojtaba Ch. Hedayati


2020, CPQ Medicine, 10(1), 01-03.





  • Submitted Articles


-          Preparation, optimization, characterization and biological activities of novel curcumin encapsulated niosomes against methicillin-resistant Staphylococcus aureus isolates (Jun 2020).



Niloufar Peirovi 1, Amir Mirzaie 2*, Reyhaneh Behdad3Mojtaba Hedayati Ch4, ImanAkbarzadeh5*, Maryam Moghtaderi 6, Fatemeh Heidari 7, Hassan Noorbazargan8, Afshin Mahmoudzadeh 2.


1 Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.


2 Department of Biology, Roudehen Branch, Islamic Azad University, Roudehen, Iran.


3 Department of Biology, Varamin-Pishva Branch, Islamic Azad University, Varamin, Iran.


4 Department of Medical Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran


5 Department of Chemical and Petrochemical Engineering, Sharif University of Technology, Tehran, Iran.


6 Department of Nanotechnology, Faculty of Advance Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran


7 Department of Chemical Engineering, Faculty of Engineering, University of Tehran, Tehran, Iran.


8 Department of Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical


 *Corresponding authors:


Dr. Amir Mirzaie, E-mail: [email protected]


Iman Akbarzadeh, E-mail: [email protected]



-                      Country Quarantine during COVID19: Critical or Not? (March 2020)


Noosha Samieefar1,2, Reza Yari Boroujeni2, Mahnaz Jamee3, Melika Lotfi4, Mohammad Rasul Golabchi5, Alireza Afshar6, Pouya Darzi 7, Mohammad Amin Kazeei Tabari7, Morteza Abdullatif Khafaie8, Amin Tamadon6, Nastaran Samimi9, Mojtaba Farjam9, Fatemeh Shiravi2, Narges Farshidi10, Mojtaba Hedayati Ch11, Rasoul Nasiri Kalmarzi12, Roya Kelishadi13, Nima Rezaei14, 15



  1. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  2. USERN Office, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. USERN Office, Alborz University of Medical Sciences, Karaj, Iran
  4. USERN Office, Zanjan University of Medical Sciences, Zanjan, Iran
  5. USERN Office, Isfahan University of Medical Sciences, Isfahan, Iran
  6. USERN Office, The Persian Gulf Biomedical sciences research institute, Bushehr, Iran
  7. USERN Office, Mazandaran University of Medical Sciences, Sari, Iran
  8. USERN Office, Ahvaz Jundishapur University of Medical Sciences, Tehran, Iran
  9. USERN Office, Fasa University of Medical Sciences, Fasa, Iran
  10. USERN Office, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
  11. USERN Office, Guilan University of Medical Sciences, Guilan, Iran
  12. USERN Office, Kurdistan University of Medical Sciences, Kurdistan, Iran
  13. USERN Office, Research Institute for Primordial Prevention of Non-Communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
  14. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  15. USERN Headquarter, Universal Scientific Education and Research Network (USERN), Tehran, Iran


Corresponding author: Nima Rezaei, MD, PhD


Research Center for Immunodeficiencies, Children's Medical Center Hospital, Dr. Qarib St, Keshavarz Blvd, Tehran 14194, Iran; Tel: +9821-6692-9234; Fax: +9821-6692-9235; E-mail:
[email protected]


-          Corresponding author: Nima Rezaei, MD, PhD


-                     Research Center for Immunodeficiencies, Children's Medical Center Hospital, Dr. Qarib St, Keshavarz Blvd, Tehran 14194, Iran; Tel: +9821-6692-9234; Fax: +9821-6692-9235; E-mail: [email protected]



-                      Study of Human Skin-derived-wild type- Lipopolysaccharide Toxicity Effects at Unfolded Protein Response Machinery and Calcium homeostasis in vivo
(
Feb 2020)



-                  Hedayati Ch. Ma, Shariyari M
b, Abedinzade M c, Golshekan M d, Nagheli Ae, and Badlou BAf*


-                   


-                  a: Cellular and Molecular Research Center, Faculty of medicine, Guilan University of Medical Sciences, Rasht, Guilan, Iran.


-                  b: Department of Microbiology, Guilan University of Medical Sciences (GUMS), Rasht, Guilan, Iran.


-                  c: Medical Biotechnology Research Center, Department of Physiology, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.


-                  d: Medical Biotechnology Research Center, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.


-                  e: Microbial toxins physiology group, Universal Scientific Education and Research Network (USERN), Rasht, Iran.


-                  e: BBAdvies and Research, Research and Development Dept. Zeist, The Netherlands.



-                 * Correspondence: Dr. Bahram A. Badlou, PhD Hematology, BBAdvies and Research, research and Development Dept. Zeist, The Netherlands tel. +31302211328;
[email protected]



-                      Cytokine overexpression induced by LOS endotoxins might increase risks of random organs’ shut down (Feb 2020)


-           


-                      Hedayati Ch. M.a Nagheli A.b, Sheikhi R.,b Atrkarrousan Z.,c, and Badlou BA.d*


-                       


-                      a: Cellular and molecular Research Center, Faculty of medicine, Guilan University of Medical Sciences, Rasht, Guilan, Iran.


-                      b:
Department of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Guilan, Iran.


-                      c: Guilan University of Medical Sciences, Faculty of medicine, Rasht, Guilan, IRAN.


-                      d: BBAdvies and Research, Research and Development Dept. Zeist, The Netherlands


-                       


-                      *Correspondence: Dr. Bahram Alamdary Badlou, PhD Hematology, BBAdvies and Research, Research and Development Dept. Zeist, The Netherlands tel. +31302211328;
[email protected]



-                      An Appropriate Circadian Dark Phase May Improve Melatonin Antioxidant Capacity of patients to Prevent Sepsis-Related Processes
(Feb 2020)



-          Hedayati Ch M.,a, Musavi S.,b Nagheli A.,b*
Gazor R.,c Atrkaroshan R.,d Habibipour Fatide R.,e1 Mirzajani E.,e2 , Khakpor Taleghani B.,f and Badlou BAg*


-                      a Cellular and molecular research center, Faculty of medicine, Guilan University of Medical Sciences, Rasht, Iran.


-          b Department of Microbiology, Faculty of medicine, Guilan University of Medical Sciences, Rasht, Guilan, IRAN.


-          b* Microbial toxins physiology group, Universal Scientific Education and Research Network, Rasht, Iran


-          c Cellular and molecular research center, Faculty of medicine (Department of Anatomy), Guilan University of Medical Sciences, Rasht, Iran


-          d Guilan University of Medical Sciences, Rasht, Iran


-          e1 Cellular and molecular research center (Department of Biochemistry), Faculty of medicine, Guilan University of Medical Sciences, Rasht, Iran


-          e2 Cellular and molecular research center (Department of Biochemistry), Faculty of medicine, Guilan University of Medical Sciences, Rasht, Iran


-          f  Department of Physiology, Faculty of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran


-          g* BBAdvies and Research, research and Development Dept. Zeist, The Netherlands



-          *Correspondence: Dr. Bahram A. Badlou, PhD Hematology, BBAdvies and Research, Research and Development Dept. Zeist, The Netherlands tel. +31302211328;
[email protected]




-                      Cardiovascular damage might cause by either infection or inflammation 
 (Feb2020)


-           Hedayati Ch M1
, Badlou BA2*



-          1 Department of Microbiology, Guilan University of Medical Sciences, Rasht, Guilan, Iran.


-          *2 Bahram Alamdary Badlou, Research and Development Dept. Zeist, The Netherlands email. [email protected].


-                      





  • International Congresses

-          Evaluation of Leshmania infection in Rhomboms opmus as a main reservoir host of Zoonotic Cutaneous leishmaniasis in Turkemen Sahara, Iran.


Mirzaei, A.; Parvizi, P; Rouhani, ; Hedayati, M; Taherkhani.


ELSEVER-International journal of infection disease. Australia parasitology-volume
١٤-supplement
٢ july ٢٠١٠- ISSN,١٢٠١-٩٧١٢


-          Detection process of Leishmania parasite in reservoir hosts of Leishmaniasis in Fars province using three routine laboratory methods and by Nested PCR of ITS-rDNA gene.


Parvizi, P., Hedayati, M, Alaee Novin, Mirzaei; Afsar Kazerooni The XIIth International congress of Parasitology, Melbourne, Australia,١٥th-٢٠th August ٢٠١٠.


-          Determination of endogenous bacterial micro flora in Anopheles species by in vitro specific microbiological tests and its confirmation by molecular analysis.


 M Hedaiati ch, E Navvabi, N Sharifi, Y Jafari, S Zakeri, A Raz, N Dinparast Djadid, National Insectarium, Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran (PII), Pasteur Avenue, P. O. BOX 1316943551, Tehran, Iran, National Insectarium, Malaria and Vector Research Group (MVRG), Biotechnology Research Center (BRC), Pasteur Institute of Iran, First international Congress of Medical bacteriology, Tabriz-Iran.


-          Isolation and detection of Leishmania species among naturally infected
Rhombomis opimus, a reservoir host of zoonotic cutaneous leishmaniasis in Turkemen Sahara, North East of Iran.


A. Mirzaei, S. Rouhani, H. Taherkhani, M. Farahmand, B. Kazemi, M. Hedayati, A. Baghaei,


B. Davari , P. Parvizi.


Molecular Systematics Laboratory, Parasitology Department, Pasteur Institute of Iran, 69 Pasteur Ave., Tehran, Iran.


-          Presenting a new ssDNA-Aptamer set against Staphylococcal Enterotoxin B, by Affinity Chromatography Assay


Mojtaba Hedayati Ch, Jafar Amani, Abbas Ali Imani Fooladi


[email protected],
[email protected],
[email protected]


Applied Microbiology Research center, Baqiyatallah University of Medical Sciences, Tehran, Iran.


15th international and Iranian congress of microbiology.


(Selected as the Best oral presentation)


-          Therapeutic use of specific aptamers for microbial metabolites


Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


18th international and Iranian congress of microbiology


-           Evaluation the relation between Alzheimer’s disease and anti-microbial toxin's vaccination in elderly individuals


 Samane Heydari*, Mojtaba Hedayati Ch, Mahmood Abedinzhade, Iraj Nikokar


18th international and Iranian congress of microbiology


-          NEISSERIA GONORRHOEAE ENDOTOXIN AND SPLEEN'S MRNA SPLICING OF XBP-1 GENE IN C57 MICE


Atabak Nagheli, Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


18th international and Iranian congress of microbiology


-          MOLECULAR STUDY OF ANTIENDOTOXIN EFFECTS OF ENDOCRINE HORMONES IN C57 ANIMAL MODEL BASED ON THE FREQUENCY OF PHYSICAL PARAMETERES


Shadi Mousavi, Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


18th international and Iranian congress of microbiology


-          THE EFFECT OF THE PSEUDOMONAS AERUGINOSA LPS ON THE UNFOLDED PROTEIN RESPONSE (UPR) IN C57 MICE


Mahla Shahryari, Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


18th international and Iranian congress of microbiology


-          COMPARISON THE EFFECTS OF DANTROLENE AND 2-AMINOETHYL DIPHENYLBORINATE ON XBP-1 MRNA GENE SPLICING IN C57 MICE TREATED WITH PSEUDOMONAS AEROGINOSA ENDOTOXIN ISOLATED FROM BURNED PATIENT'S LESION


Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


19th international and Iranian congress of microbiology


-          APPROPRIATE CIRCADIAN DARKNESS MAY HELP RECOVERY OF SEPTIC SHOCK PRODUCED BY BACTERIAL LIPOPOLYSACCHARIDE


Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


19th international and Iranian congress of microbiology


-          EVALUATION ONE MOLECULAR EFFECT OF NEISSERIA GONORRHOEAE LIPOOLIGOSACHARIDE TOXICITY IN MICE SPLEEN, BASED ON ACTIVATION OF UNFOLDED PROTEIN RESPONSE THROUGH INOSITOL REQUIRING ENZYME-1Α


Mojtaba Hedayati Ch


Guilan University of Medical Sciences Department of Medical Microbiology


19th international and Iranian congress of microbiology


· Workshops


-          Workshop on "Basics of microbiology and isolation of microbes from different sources": University of Guilan.


-          Biosafety Workshop: Pasteur Institute of Iran.


-          Immunology of Leishmania Parasites: Pasteur Institute of Iran.


-          Workshop on Apoptosis and Autophagy: Hepatitis Congress of Baqiyatallah University and Shahid Beheshti University.


-          SPSS Workshop, Baqiyatallah University of Medical Sciences.


-          Reference Manager Workshop, Baqiyatallah University of Medical Sciences.


-          EndNote Workshop, Baqiyatallah University of Medical Sciences.


-          Research Ideas Workshop, Baqiyatallah University of Medical Sciences.


-          Search strategy workshop, Baqiyatallah University of Medical Sciences.


-          Study design workshop, Baqiyatallah University of Medical Sciences.


-          Specialized Workshop on PCR and Cloning and Gene Expression, Baqiyatallah University of Medical Sciences.


-          Specialized Workshop on Extraction of Genomes from Bacteria, Baqiyatallah University of Medical Sciences.


-          Specialized Cell Culture Workshop, Baqiyatallah University of Medical Sciences.


-          Specialized Bioinformatics Workshop, Baqiyatallah University of Medical Sciences.


-          ELISA Workshop on Immunological Methods, Baqiyatallah University of Medical Sciences.


-          Workshop on R&D Management, Change Management, May 2013, Tehran, Ministry of Industry, Mine and Trade.


-          Project Management Course Workshop, Specialized Association of Research and Development Centers and Industries and Mines, May 2013, Tehran Ministry of Industry, Mine and Trade.


-          Workshop on Economic Evaluation of Projects, Specialized Association of Research and Development Centers and Industries and Mines, Tehran Ministry of Industry, Mine and Trade.


-          Creativity and Innovation Workshop for Graduate Research and Development Managers, Specialized Association of Research and Development Centers, Industries and Mines, Tehran Ministry of Industry, Mine and Trade.


-          Workshop on Research and Development Activities in Enterprises (Challenges and Solutions), Specialized Association of Research and Development Centers and Industries and Mines, Tehran, Building 2 Ministry of Industry, Mine and Trade.


-          Strategic Planning Workshop Specialized Association of Research and Development Centers of Industries and Mines, Tehran, Building 2 Ministry of Industry, Mining and Trade.


-          Creativity and Innovation Workshop, Specialized Association of Research and Development Centers and Industries and Mines, Tehran, Building 2 Ministry of Industry, Mining and Trade.


-          Workshop on Change and Research and Development Management, Specialized Association of Research and Development Centers and Industries and Mines, Tehran, Building 2 Ministry of Industry, Mining and Trade.


-          Workshop "Design and Analysis of Multiple-Choice Questions (MCQ)", Guilan University of Medical Sciences.


-          Research Ethics Workshop. Guilan University of Medical Sciences.


-          Startup Workshop, Vice Chancellor of Research and Technology, Guilan University of Medical Sciences.


-          Workshop "Knowledge Base Registration Company", Vice Chancellor of Research and Technology of Guilan University of Medical Sciences.


-          Workshop "Webinar System Training", Guilan University of Medical Sciences.


-          Workshop "Introduction and Application of MOOC in Medical Education", Vice Chancellor of Education, Guilan University of Medical Sciences.


-          Workshop "Introduction and Implementation of E-Learning Management System (LMS)", Guilan University of Medical Sciences.


-          Workshop "Scientific Research and Research Methodology Workshop", Vice Chancellor of Research and Technology of Guilan University of Medical Sciences.


-          Workshop on Laboratory Animal Ethics, Vice Chancellor of Research and Technology, Guilan University of Medical Sciences.


-          Clinical Trial Workshop, Vice Chancellor of Research and Technology, Guilan University of Medical Sciences.


-          Workshop on English-language scientific and business correspondence and negotiations, Ministry of Agriculture Jihad, Agricultural Research, Education and Language Organization, Agricultural Research and Training Center of Guilan.


· Inventions


  Patents (Certified in Iran)


-          Study of the molecular nature of electrophoresis process and proposing
one hypothesis and patent of the device


(Centralizing Magnetic Field Electrophoresis Apparatus = CMFEA)


-          A research-protection device to catch insects


-          A multifunctional scalpel-holder tool


-          An artificial insect feeding machine


-          A Homogenizer machine to extract DNA from tissue


-          A semi-automatic mixer and spiral microbial cultivation device


-          A modified imaging and Morris Water Maze temperature control system (patent-pending)


Ongoing Patents(patent-pending)


-          Nano-Diphtheria toxoid vaccine for Alzheimer’s disease (AD).


-                         LPS-cocktail vaccine for Multiple sclerosis (MS).
 


-          A protocol and device for non-pyrogenization of laboratory instruments.


-          Prognostic toxic shock detection kit.


-          Nano-antibacterial wound bandage.


-          Bacterial Fuel Electric Nano Bio-Reactor


-          Bacterial LPS chelator nano-polymer


-          LPS Detection Kit in Injectable Products based on ssDNA Aptamer.


-          Production of HPLC column purification of aflatoxin based on ssDNA aptamer.


-          Aflatoxin Diagnostic Kit Based on ssDNA Aptamer.


-          A semi-automatic quadcopter for microbial sampling from inaccessible resources.




  • List of Research Projects and Theses Implemented and Running















































Operation Lab execution time Type of cooperation Research Project Title Number
Pasteur Institute of Iran 2010 Research fellow PP-190 Evaluation of Leishmania infection in Rhombomisopimus as a main reservoir host of zoonotic cutaneous Leishmaniasis in TurkemenSahra, Iran
1
Pasteur Institute of Iran 2010 Research fellow PP-200 First detection of Leishmania parasite in Merioneslybicus reservoir of zoonotic cutaneous Lieshminiasis in TurkemenSahra
2
Pasteur Institute of Iran 2010 Research fellow PP-199 Detection process of Leishmania parasite in reservoir host of Lieshmaniasis in Fars province using three routine laboratory methods and by Nested PCR of ITS-rDNA gene
3
Baqiyatallah university of medical sciences
2016 Research fellow Isolation of new ssDNA aptamer against staphylococcal enterotoxin B based on CNBr-activated sepharose-4B affinity chromatography
4
Baqiyatallah university of medical sciences
2016 Research fellow Distribution of high-level mupirocin resistance among clinical MRSA
5

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