Academic Director of the Oncogenomic Core Facility
Chief of Division of Cancer Genomics and Epigenetics
Director of the Cancer Epigenetics Research Program
Professor, Biochemistry & Molecular Biology
Professor, Dr. John T. Macdonald Foundation Department of Human Genetics
Research Interests
My laboratory has made a number of important contributions over the past several years in identifying and characterizing critical mediators of epigenome. These include a number of chromatin remodeling (human NURF, CERF, WCRF/ACF) and chromatin modifyingUTX/MLL3/4, JARID1d, LSD1-CoREST complexes. Importantly, the emerging roles for non-coding RNAs in epigenetic regulation and their crosstalk with chromatin regulatory complexes persuaded us to characterize the key players in the biogenesis and effector function of non-coding RNAs.
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