Usern_member

Shinya Kimura

USERN Advisory Board

Education


1980-1986 Jichi Medical School, Japan

1996-1998 Postdoctoral Fellow, Division of Cancer and Haematology, The Walter andEliza Hall Institute, Australia

2000-2001 Postdoctoral Fellow, Dep. of Haematology, Frankfurt University, Germany 


Employment Experience


2002-2009 Assistant Professor, Dep. Transfusion Medicine and Cell Therapy, Kyoto University Hospital

2009-present Professor and Chairman, Division of Hematology, Respiratory Medicine and Oncology, Faculty of Medicine, Saga University

2010-2016 Director, Cancer Center, Saga University Hospital

2014-present Vice President, Saga University Hospital

2017-present Professor, Dep. Drug Discovery and Biomedical Sciences (Serve concurrently as above)


Field of Specialization



  1. Hematology, General pharmacology



Research Topics and Results



  1. Clinical features of Japanese patients with exacerbations of chronic obstructive pulmonary disease 202012
  2. Monitoring of tumor cells by flow cytometry permits rapid evaluation of disease progression in monomorphic epitheliotropic intestinal T-cell lymphoma  202012
  3. Clinical Manifestations of Allergic Bronchopulmonary Aspergillosis without Major Features of Asthma Diagnosed by the New Criteria in Japan 202011
  4. Ibrutinib-Induced Cardiac Tamponade in Chronic Lymphocytic Leukemia 202011
  5. HLA polymorphisms are associated with treatment-free remission following discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia 202010
  6. Biomarkers for Overweight in Adult-Onset Asthma 202010
  7. A methotrexate-associated lymphoproliferative disorder expressing CD10 and BCL6 with the IGH/CCND1 translocation 202010
  8. 一般演題4
    化学療法抵抗性の十二指腸原発印環細胞癌の一例 202010
  9. Evaluation of olfactory dysfunction to estimate the presence of eosinophilic chronic rhinosinusitis in patients with asthma 202009
  10. First-Line Treatment with Tiotropium/Olodaterol Improves Physical Activity in Patients with Treatment-Naïve Chronic Obstructive Pulmonary Disease 202009
  11. Efficacy of dupilumab and biomarkers for systemic corticosteroid naïve allergic bronchopulmonary mycosis 202009
  12. 肥満合併喘息モデルにおけるマクロライドEM900の治療効果 202009
  13. HIV患者に発症した肺クリプトコッカス症56例の臨床的特徴の解析 202009
  14. 肥満喘息の臨床的特徴に基づいたマウスモデルによる腸内細菌叢を標的とした難治化の制御 202009
  15. 当院で経験した腸管スピロヘータ症の2 202009
  16. 3.化学療法による血管障害の機序と管理(2BCR-ABLチロシンキナーゼ阻害薬 202009
  17. Targeting aberrant DNA hypermethylation as a driver of ATL leukemogenesis using the new oral demethylating agent OR-2100 202008
  18. Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells 202008
  19. DAA治療施行C型慢性肝疾患患者のSVR3年後paired-biopsyによる,病理学的及び血清肝線維化指標の推移の検討 202008
  20. 2.慢性骨髄性白血病(2)初発慢性期の慢性骨髄性白血病の治療 202008
  21. 低頻度抗原Cobに対する抗体を保有する一症例 202007
  22. Allelic polymorphisms of KIRs and antitumor immunity against chronic myeloid leukemia 202007
  23. Surrogate Markers for Treatment-Free Remission in Patients With Chronic Myeloid Leukemia 202007
  24. J-SKI will be able to elucidate whether the renal function recover or not after discontinuation of tyrosine kinase inhibitors 202007
  25. Origin of circulating free DNA in patients with lung cancer 202007
  26. Assessment of estimated glomerular filtration rate in patients with chronic myeloid leukemia following discontinuation of tyrosine kinase inhibitors 202007
  27. Pharmacokinetics of dasatinib in a hemodialysis patient with chronic myeloid leukemia and chronic kidney disease 202007
  28. Accelerated Phase of Atypical Chronic Myeloid Leukemia with Severe Disseminated Intravascular Coagulation at Initial Presentation 202006
  29. Successful Anti-TNF-Alpha Therapy for Crohn's Disease After Allogeneic Stem Cell Transplantation: A Case Report 202006
  30. Does patient sex play a role in treatment-free remission in chronic myeloid leukemia? 202006
  31. Immune dysregulation syndrome with de novo CTLA4 germline mutation responsive to abatacept therapy 202006
  32. 当院におけるABO亜型の検出状況と臨床への結果報告について 202005
  33. 有毛細胞白血病 202005
  34. Development of an application for management of drug holidays in perioperative periods 202005
  35. Reconstitution of NK cells expressing KIR3DL1 is associated with reduced NK cell activity and relapse of CML after allogeneic hematopoietic stem cell transplantation 202005
  36. Clinical impact of advanced chronic kidney disease in patients with non-HIV pulmonary cryptococcosis 202004
  37. Budget impact analysis of treatment-free remission in nilotinib-treated Japanese chronic myeloid leukemia patients 202004
  38. Ph急性リンパ性白血病 202004
  39. Terminal deoxynucleotidyl transferase (TdT) negative early T cell precursor acute lymphoblastic leukemia (ETP-ALL) with spontaneous acute kidney injury 202004
  40. Durable remission of post-transplant relapsed FLT3-ITD AML in response to gilteritinib administration after a second transplant from the same donor 202003
  41. Treatment-free remission after first-line dasatinib discontinuation in patients with chronic myeloid leukaemia (first-line DADI trial): a single-arm, multicentre, phase 2 trial 202003
  42. Phosphorylated ERK1/2 in CD4 T cells is associated with acute GVHD in allogeneic hematopoietic stem cell transplantation 202002
  43. ペンブロリズマブ投与後に免疫関連有害事象として全身性エリテマトーデス・抗リン脂質抗体症候群を発症した1症例 202002
  44. 肺癌患者における血漿遊離DNAの特性 202002
  45. Epstein-Barr virus-positive diffuse large B cell lymphoma, not otherwise specified, carrying a t(19;22)(q13;q11) translocation. 202002
  46. 腹腔鏡下試験開腹術が有用であった表在型胃癌の1 202001
  47. Clinical impact of the CONUT score in patients with multiple myeloma 202001
  48. Role of cancer immunology in chronic myelogenous leukemia 202001
  49. The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model 202001
  50. 腎偶発腫瘍で発見され、イブルチニブ単剤治療により1年半安定状態を得ているFCR後再発小リンパ球性リンパ腫 2020
  51. Concomitant Nephrotic Syndrome with Diffuse Large B-cell Lymphoma: A Case Report 2020
  52. The Nonantibiotic Macrolide EM900 Attenuates House Dust Mite-Induced Airway Inflammation in a Mouse Model of Obesity-Associated Asthma 2020
  53. Association of Genetic Polymorphisms With Afatinib-induced Diarrhoea 2020
  54. びまん性大細胞型B細胞リンパ腫に合併した続発性膜性腎症の一例 2020
  55. CBFB-MYH11を伴うCML急性転化の1症例 2020
  56. 血液製剤中の不規則抗体検査陽性率と交差適合試験副試験の必要性について 201912
  57. Immunohistochemical localization of afatinib in male rat intestines and skin after its oral administration 201911
  58. Significance of FLT3-tyrosine kinase domain mutation as a prognostic factor for acute myeloid leukemia. 201911
  59. Mesalazine-induced airway obstruction: Utility of pulmonary function testing in drug-induced lung diseases. 201911
  60. Severe infusion reaction, anti-rituximab antibodies and lymphoma. 201911
  61. 慢性骨髄性白血病 201910
  62. Japan's high-cost medical expense benefit system could be an obstacle to promoting generic imatinib 201910
  63. Naked antisense double-stranded DNA oligonucleotide efficiently suppresses BCR-ABL positive leukemic cells. 201910
  64. BCR-ABL1- and CBFB-MYH11- positive chronic myeloid leukemiapresenting with primary blast crisis and marrow fibrosis 201910
  65. Discontinuation due to immune-related adverse events is a possible predictive factor for immune checkpoint inhibitors in patients with non-small cell lung cancer. 201909
  66. Assessment of tumor volume and density as a measure of the response of advanced hepatocellular carcinoma to sorafenib: Application of automated measurements on computed tomography scans 201908
  67. Primary Chest Wall MYC/BCL6 Double-hit Lymphoma with t (3;7) (q27;p12) and t (8;14) (q24;q32) Translocations. 201907
  68. Locally distributed multicentric plasmacytomas in the ileum secondary to lymphoma chemoimmunotherapy 201906
  69. HMGCLL1 is a predictive biomarker for deep molecular response to imatinib therapy in chronic myeloid leukemia 201906
  70. Mogamulizumab for the Treatment of Adult T-cell Leukemia/Lymphoma 201906
  71. CMLに対する新規治療薬の開発状況 201905
  72. Oral ulceration: an unusual manifestation of lymphomatoid granulomatosis 201905
  73. Development of a sandwich enzyme-linked immunosorbent assay for the quantification of ponatinib in serum 201904
  74. Feasibility of the imatinib stop study in the Japanese clinical setting: delightedly overcome CML expert stop TKI trial (DOMEST Trial) 201904
  75. A new highly sensitive real-time quantitative-PCR method for detection of BCR-ABL1 to monitor minimal residual disease in chronic myeloid leukemia after discontinuation of imatinib 201903
  76. Is clinicopathological distinction of mucosa-associated lymphoid tissue lymphoma from Waldenstrom macroglobulinemia essential in MYD88 L265P mutation-positive cases? 201903
  77. C/EBPβ is a critical mediator of IFN-α-induced exhaustion of chronic myeloid leukemia stem cells 201902
  78. Development of a competitive enzyme-linked immunosorbent assay for therapeutic drug monitoring of afatinib 201902
  79. Clinical impact of the CONUT score and mogamulizumab in adult T cell leukemia/lymphoma 201902
  80. Epstein-Barr virus-related diffuse large B-cell lymphoma in mogamulizumab-treated adult T-cell leukemia with incomplete T-cell reconstitution. 201902
  81. チロシンキナーゼ阻害剤によるCML治療の効果判定法と服薬中止の可能性 201901
  82. 成人T細胞白血病/リンパ腫におけるエピジェネティクス異常を標的にした創薬 201901
  83. The presence and possible role of virus-host chimeric transcripts in adult T-cell leukemia-lymphoma. 2019
  84. An effect of novel non-antibiotic macrolide EM900 in HDM-induced airway inflammation mice model 2019
  85. 肺がん患者における血漿遊離DNAの生物学的特性の検討 2019
  86. Nab-paclitaxel plus ramucirumab combination therapy as second-line with advanced gastric cancer:Retrospective study 2019
  87. FLT3-ITD陽性急性骨髄性白血病を対象とした13番染色体長腕ヘテロ接合性消失の解析  2019
  88. Mogamulizumb投与後にもT細胞再構築が得られずEBV関連中枢神経原発B細胞リンパ腫を発症したATL 2019
  89. 慢性骨髄性白血病に対する新規経口DNA脱メチル化剤 OR-2100の効果の検討 2019
  90. Successful treatment with anti-TNF-α therapy for Crohn’s disease after umbilical cord blood transplantation 2019
  91. The presence and possible role of virus-host chimeric transcripts in HTLV-1-infected cells.  2019
  92. 実診療におけるCOPD吸入療法の妥当性に関する解析 2019
  93. Liquid biopsyを用いたアファチニブ耐性化機序の検討 2019
  94. デュルバルマブ投与後にステロイド抵抗性の放射線性肺臓炎と薬剤性肺障害を発症し、インフリキシマブ投与を行った一例 2019
  95. Liquid biopsyを用いたアファチニブ獲得耐性機序の検討 2019
  96. IPEX症候群である生後3か月の児での不規則抗体抗Eの産生を認めた一症例 2019
  97. 超高齢DLBCL患者における臨床学的特徴についての後方視的研究  2019
  98. 高度腹水を有する切除不能・進行再発癌に対する腹水濾過再静注療法併用化学療法の後方視的検討 2019
  99. Clinical features and outcome of very elderly patient with diffuse large B-cell lymphoma  2019
  100. 喘息増悪におけるマクロライド誘導体EM900の治療効果 2019
  101. マクロライド誘導体EM900による喘息増悪に対する治療の試み 2019
  102. 喘息患者における嗅覚障害と好酸球性副鼻腔炎合併に関する臨床的検 2019
  103. 2つの異なる免疫表現型を有した初期前駆T細胞性急性リンパ芽球性白血病と考えられた1  2019
  104. ベンラリズマブ投与症例の臨床的検討 2019
  105. RhD血液型不適合造血幹細胞移植後、移植前の患者血液型となった1例 2019
  106. 自己末梢血幹細胞採取1日目の採取不良例に対するplerixafor投与例での採取結果の検討 2019
  107. t(19;22)(q13.1;q11.2)を認めたEBV陽性DLBCLの一例  2019
  108. 肺がん患者における血漿遊離DNAの特性 2019
  109. オシメルチニブ投与中に小細胞肺癌へ形質転換したEGFR陽性肺腺癌に対して、化学療法とオシメルチニブの交代両方が奏効した一例.  2019
  110. ARS抗体陽性間質性肺炎の臨床的検討 2019
  111. 重篤なDICを呈し急性前骨髄球性白血病との鑑別を要した非定型慢性骨髄性白血病 2019
  112. IGH/CCND1転座を伴ったメトトレキサート関連リンパ増殖性疾患の1 2019
  113. 高力価抗リツキシマブ抗体の産生と重症infusion reactionを伴った濾胞性リンパ腫の1 2019
  114. irAE中止症例における、効果と予後の後方視的検討 2019
  115. Birt-Hogg-Dube症候群の1家系内の2例の臨床的特徴 2019
  116. t(3;7)(q27;p12)及びt(8;14)(q24;q32)転座を有する胸膜原発MYC/BCL6 double-hit lymphoma1 2019
  117. Liquid biopsyを用いたアファチニブ耐性化機序の検討 2019
  118. 頭部MRIの脳室拡大所見を契機に診断した肺癌
    髄膜癌腫症の臨床的検討 2019
  119. Nivolumabによる免疫関連有害事象に対するステロイド治療により発症した難治性感染症 2019
  120. 喘息患者における好酸球性副鼻腔炎の合併と嗅覚障害に関する解析 2019
  121. 当院におけるABO亜型の検出状況と臨床への結果報告について 2019
  122. メサラジンによる薬剤性肺障害の一例 2019
  123. III.白血病 D.慢性骨髄性白血病(CML 5.TKIsによるCML治療のモニタリングと予後予測 2019
  124. Acute myeloid leukemia with t(19;21)(q13;q22) transformed from myelodysplastic syndrome with marked eosinophilia. 2019
  125. Identification of the BRAF V600E mutation in Japanese patients with hairy cell leukemia and related diseases using a quenching probe method.  2018
  126. Current Status and Problems of T790M Detection, a Molecular Biomarker of Acquired Resistance to EGFR Tyrosine Kinase Inhibitors, with Liquid Biopsy and Re-biopsy. 2018
  127. Targeting of BMI-1 expression by the novel small molecule PTC596 in mantle cell lymphoma.  2018
  128. Mechanisms of acquired resistance to afatinib clarified with liquid biopsy 2018
  129. Automated DNA extraction using cellulose magnetic beads can improve EGFR point mutation detection with liquid biopsy by efficiently recovering short and long DNA fragments. 2018
  130. Final 3-year results of the Dasatinib Discontinuation Trial in Patients with Chronic Myeloid Leukemia who received dasatinib as a second line treatment 2018
  131. Prognostic impact of Acute myeloid leukemia with low allelic ratio FLT3-ITD and NPM1 mutation. 2018
  132. Anxiety and depression associated with tyrosine kinase inhibitor discontinuation in patients with chronic myeloid leukemia 2018
  133. Investigation of Appropriate Pre-analytical Procedure for Circulating Free DNA from Liquid Biopsy. 2018
  134. Relationship between the duration of trimethoprim/sulfamethoxazole treatment and the clinical outcome of pulmonary nocardiosis. 2018
  135. Allelic polymorphisms of KIRs and HLAs predict favorable responses to tyrosine kinase inhibitors in CML. 2018
  136. The Current State of Therapeutic Development for Rare Cancers in Japan, and Proposals for Improvement. 2018
  137. Successful treatment of post-transplant relapsed adult T cell leukemia after cord blood transplantation with low-dose, short-term lenalidomide. 2018
  138. A case of osimertinib-resistant lung adenocarcinoma responded effectively to alternating therapy. 2018
  139. Synchronous mantle cell lymphoma and lung adenocarcinoma presenting in a pleural effusion: a rare tumor combination and a potential pitfall of cytodiagnosis 2018
  140. Successful autologous hematopoietic stem cell transplantation followed by bortezomib maintenance in a patient with relapsed CD138-low multiple solitary plasmacytomas harboring 17p deletion. 2018
  141. Primary effusion lymphoma-like lymphoma with a T cell phenotype 2018
  142. Three coexisting lymphomas in a single patient: Composite lymphoma derived from a common germinal center B-cell precursor and unrelated discordant lymphoma. 2018
  143. Primary Pulmonary Colloid Adenocarcinoma: How Can We Obtain a Precise Diagnosis? 2018
  144. Sj?gren Syndrome Complicated with Cystic Lung Disease and Pulmonary Amyloidosis.  2018
  145. Tocilizumab for severe cytokine-release syndrome after haploidentical donor transplantation in a patient with refractory Epstein-Barr virus-positive diffuse large B-cell lymphoma. 2018
  146. Characteristics of circulating tumor DNA in lung cancer patients.  2018
  147. ABL Tyrosine Kinase Inhibitors and Minimal Residual Disease Negativity during Treatment and Stop  2018
  148. Evaluation of low level detection of major BCR-ABL1 mRNA in chronic myeloid leukemia (DOMEST additional study) 2018
  149. irAE, Possible Predictive Markers for Immune Checkpoint Inhibitors 2018
  150. Mechanisms of acquired resistance to afatinib clarified with liquid biopsy 2018
  151. Investigation of origin of circulating free DNA: Is exosomal DNA the carrier? 2018
  152. Investigation of origin of circulating free DNA: Is EV the carrier?  2018
  153. An Effect of Clarthromycin Treatment in HDM-Induced Allergic Airway Inflammation in Mice 2018
  154. Characteristics of circulating free DNA in lung cancer patients.  2018
  155. 肺がん患者における血漿遊離DNAの特性. 2018
  156. Molecular tageting therapy for CML and stop studies 2018
  157. 分子標的薬と心血管障害 2018
  158. 液体生検はどのように使い分けるべきか? 2018
  159. irAE,
    効果・予後予測因子としての可能性 2018
  160. 単一上皮親和性腸管T細胞リンパ腫に対しタンデム自家・同種移植を施行した一例 2018
  161. A prospective study of predictive biomarkers for venous thromboembolism in Japanese patients with metastatic or unresectable cancer 2018
  162. Analysis of a novel mutation of ERBB2 in cancer of unknown primary 2018
  163. 日本人の切除不能進行がん患者での静脈血栓塞栓症の発症予測に関する前向き観察研究 2018
  164. 新たな核酸医薬技術、レナ核酸によるBCR-ABLの抑制効果 2018
  165. Predictive factors for adverse events of pemetrexed in non-small cell lung cancer 2018
  166. 急性骨髄性白血病におけるFLT3-ITD低アレル比とNPM1の予後因子としての重要性 2018
  167. Clarification of mechanisms of acquired resistance for afatinib using plasma samples. 2018
  168. Liquid biopsyを用いたアファチニブ耐性化機序の検討 2018
  169. Investigation of origin of circulating free DNA: Are extracellular vesicles the carrier? 2018
  170. Circulating free DNAExtracellular vesicles associated DNAの関係についての検討.  2018
  171. HDM気道炎症に対するマクロライドの治療効果. 2018
  172. HDM誘導アレルギー性気道炎症に対するクラリスロマイシンの治療効果 2018
  173. 喘息モデルにおけるclodronate liposomeによるIL-33抑制効果の解析. 2018
  174. 慢性骨髄性白血病に対するチロシンキナーゼ阻害薬治療中に固形がんを合併した5症例の検討 2018
  175. 肺がん患者における血漿遊離DNAの特性 2018
  176. シェーグレン症候群を合併した抗ARS抗体陽性間質性肺炎の一例. 2018
  177. 多発性粒状影。結節影・浸潤影を呈した肺クリプトコッカス症の一例. 2018
  178. 免疫チェックポイント阻害剤により薬剤性肺障害を来たした非小細胞肺癌の3. 2018
  179. 当院における液体生検と再生検の現状と問題点、その克服に向けて 2018
  180. 血漿分子マーカーを用いたアファチニブ獲得耐性機序の検討 2018
  181. 画像診断が術前診断に有用であった肺colloid adenocarcinomaの一例.  2018
  182. 慢性進行性肺アスペルギルス症に続発した好酸球性肺炎の一例 2018
  183. 心肺運動負荷試験によりCOPD患者の運動耐容能低下の要因を診断し運動処方を行った症例 2018
  184. 免疫グロブリン大量静注療法により抗Aが移行し、O型赤血球製剤を輸血した1 2018
  185. Efficacy of reduced-dose dasatinib as a subsequent therapy in patients with chronic myeloid leukemia in the chronic phase: The LD-CML study of the Kanto CML Study Group. 2018
  186. Chemotherapy for primary mediastinal yolk sac tumor in a patient undergoing chronic hemodialysis: a case report. 2017
  187. Elderly patients with chronic myeloid leukemia benefit from a dasatinib dose as low as 20 mg. 2017
  188. Functional analysis of Discoidin domain receptor 2 mutation and expression in squamous cell lung cancer. 2017
  189. Peculiar cold-induced leukoagglutination in Mycoplasma pneumoniae pneumonia. 2017
  190. Severity and predictive factors of adverse events in pemetrexed-containing chemotherapy for non-small cell lung cancer. 2017
  191. Plasma T790M and HGF as potential predictive markers for EGFR-TKI re-challenge. 2017
  192. Automatic digital quantification of bone marrow myeloma volume in appendicular skeletons - clinical implications and prognostic significance. 2017
  193. Deep sequencing of the T cell receptor visualizes reconstitution of T cell immunity in mogamulizumab-treated adult T cell leukemia  2017
  194. Thin-section CT findings of multicentric Castleman disease changing over 10 years. 2017
  195. Pre-existing chronic interstitial pneumonia is poor prognostic factor of Goodpasture's syndrome: a case and review of the literature 2017
  196. Saturated Fatty Acid Increases Lung Macrophages and Augments House Dust Mite-Induced Airway Inflammation in Mice Fed with High-Fat Diet. 2017
  197. CMLの分子病態と治療 2017
  198. 治療/造血器腫瘍の最新治療戦略
    慢性骨髄性白血病に対するこれからの治療戦略 慢性骨髄性白血病に対するこれからの治療戦略深化する治療目標─ 2017
  199. 特集:臨床血液学 -最新情報と今後の展望2017 (骨髄系疾患)-
    慢性骨髄性白血病とNK細胞免疫 2017
  200. Persistent Gastrointestinal Angiodysplasia in Heyde's Syndrome after Aortic Valve Replacement 2017
  201. Successful Autologous Hematopoietic Stem Cell Transplantation Followed by Bortezomib Maintenance in a Patient with Relapsed CD138-low Multiple Solitary Plasmacytomas Harboring a 17p Deletion. 2017
  202. Primary effusion lymphoma-like lymphoma with a T cell phenotype 2017
  203. Three coexisting lymphomas in a single patient: composite lymphoma derived from a common germinal center B-cell precursor and unrelated discordant lymphoma 2017
  204. Tocilizumab for severe cytokine-release syndrome after haploidentical donor transplantation in a patient with refractory Epstein-Barr virus-positive diffuse large B-cell lymphoma 2017
  205. Characteristics of cell free DNA in lung cancer patients. 2017
  206. Characteristics of cell free DNA in lung cancer patients. 2017
  207. Allelic polymorphisms of KIR and HLA predict favorable responses to TKIs in CML patients. 19th Annual John Goldman Conference on Chronic Myeloid Leukemia:  2017
  208. Downregulation of BMI-1 by the small molecule PTC596 induces mitochondrial apoptosis in mantle cell lymphoma 2017
  209. Correlation and problems of re-biopsy and liquid biopsy for detecting T790M mutation. 2017
  210. Clarification of mechanisms of acquired resistance for afatinib using plasma samples. 2017
  211. DNA extraction method using cellulose magnetic beads can improve the EGFR mutation detection rate. 2017
  212. Automatic Digital Quantification of Bone Marrow Myeloma Volume in Appendicular Skeletons ? Clinical Implications and Prognostic Significance 2017
  213. HDM誘導アレルギー性気道炎症における飽和脂肪酸の役割 2017
  214. Recruited lung macrophages contribute to progression of airway inflammation in obesity asthma mice model.  2017
  215. IMPACT OF KIR3DL1*00501 IN TYROSINE KINASE INHIBITOR-TREATED CML 2017
  216. 肺がん患者における血漿遊離DNAの特性 2017
  217. ラムシルマブ投与後4週間以内に緊急手術を施行された2 2017
  218. CMLの分子病態と治療 2017
  219. 当院におけるRe-biopsyの現状と問題点 2017
  220. Ponatinib for relapsed Ph+ leukemia with T315I mutation after allogeneic stem cell transplantation 2017
  221. Targeting of BMI-1 in mantle cell lymphoma 2017
  222. 血漿分子マーカーを用いたafatinib耐性化機序の検討 2017
  223. 血漿分子マーカーを用いたafatinib耐性化機序と効果予測因子の検討 2017
  224. 血漿分子マーカーを用いたafatinib耐性化機序の検討 2017
  225. Liquid biopsyにおける適切なpre-analytical procedureとは何か 2017
  226. 高脂肪食マウスにおけるHDMによるアレルギー性気道炎症の解析(ミニシンポジウム) 2017
  227. 薬剤師アンケートによる吸入療法における地域連携の課題と展望(ミニシンポジウム) 2017
  228. COPD患者の身体活動量評価としての国際標準化身体活動質問票(IPAQ)日本語版の妥当性の検討 2017
  229. CML患者のTKI治療効果はKIR3DL1 allele及びHLA-B多型のgenotypingを行うことで予測できる 2017
  230. 慢性骨髄性白血病におけるKIRHLAのアリル多型はチロシンキナーゼ阻害剤の治療効果と相関する 2017
  231. 劇症型心筋症として発症した骨髄移植後のcGVHD1 2017
  232. B+O血液型キメラにおいて不規則抗Bが疑われた一症例 2017
  233. 当院におけるROS1陽性肺癌の2例 2017
  234. COPD患者における心肺運動負荷試験(CPET)の検討 2017
  235. 慢性骨髄性白血病におけるチロシンキナーゼ阻害剤の効果は KIRアリルと相関する 2017
  236. 当院で作製した輸血検査DVDを用いた地域への貢献について 2017
  237. 高感度EGFR遺伝子変異検出法におけるDNA自動抽出法の有用性 2017
  238. 再々生検にてT790M陽性を確認し得たEGFR遺伝子変異陽性肺癌の1 2017
  239. 5q- syndrome-like features as the first manifestation of myelodysplastic syndrome in a patient with an unbalanced whole-arm translocation der(5;19)(p10;q10) 2017
  240. Paraneoplastic sarcoidosis in multiple myeloma 2017
  241. Characteristics and prognosis of microscopic polyangiitis with bronchiectasis, Journal of Thoracic Disease 2017
  242. The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells 2017
  243. Mutation profile of B-raf gene analyzed by fully automated system and clinical features in Japanese melanoma patients 2017
  244. Detection of KRAS Mutations in plasma DNA using a fully automated rapid detection system in colorectal cancer patients 2017
  245. 第一世代EGFR-TKI獲得耐性例におけるafatinib治療効果と血漿分子マーカー測定結果の検討 2016
  246. 顕微鏡的多発血管炎に合併する気管支拡張症の予後解析 2016
  247. 血栓性微小血管障害症に合併した肺胞出血の1 2016
  248. 腺癌とMantle cell lymphomaを同時に胸水中に認めた一例 2016
  249. 血漿を用いたEGFR-TKIs獲得耐性機序の解明 2016
  250. ダサチニブ内服およびメソトレキサート髄注施行後硬膜下血腫を来たしたフィラデルフィア染色体陽性急性リンパ球性白血病(Ph陽性ALL) 2016
  251. 骨形成を伴った原発性肺がんの1例 2016
  252. ベバシズマブ併用化学療法が著効した原発不明低分化腺癌の1例 2016
  253. 導入化学療法後に急速に進行した縦隔原発混合型胚細胞腫瘍の1 2016
  254. 血漿分子マーカーを用いたafatinib耐性化機序と効果予測因子の検討 2016
  255. 同種血輸血における免疫担当細胞の動態に関する解析 2016
  256. 広範な皮下血腫と高度の貧血を呈した真性多血症と第XIII/13因子(F13)欠乏症の合併症例 2016
  257. IL-33 from inflammatory monocytes recruited to lung contributes to HDM-Induced airway inflammation 2016
  258. 単球由来IL-33HDMによる気道炎症に関与する 2016
  259. 当院における呼吸リハビリテーションの現状と課題 2016

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