Masayoshi Yamaguchi

Masayoshi Yamaguchi, Ph.D., IOM, FAOE, DDG, DG

Masayoshi Yamaguchi (born 1947 in Atami, Japan) is a Japanese scientist and researcher in the biomedical fields related to biochemistry, endocrinology, metabolism, cancer biology, nutrition, pharmacology, and toxicology.
      He graduated with a bachelor's degree from Shizuoka College of Pharmacy in 1971,
Yamaguchi's research focused on bone and calcium endocrinology, metabolism, cell calcium signaling, gene regulation, nutritional osteoporosis prevention, carcinogenesis, and cancer therapy. Yamaguchi discovered the novel protein and genes, which were named as Regucalcin and RGPR-p117. Yamaguchi has over 20 patents, has published over 600 papers and review articles, four books, and has edited 10 further books. He served as an editorial board member on more than 80 international journals. Yamaguchi was appointed to the Japanese Society for Biochemistry and the Endocrine Society of Japan. He was a member of the New York Academy of Sciences from 1996 to 2012, the American Society for Bone and Mineral Research from 1999 to 2016, and has been a member of the American Society for Biochemistry and Molecular Biology since 2005. and obtained his Ph.D in Pharmaceutical Sciences in 1976 in Japan. He was engaged as a Research Associate and Assistant Professor in Shizuoka College from 1973 to 1987, as Assistant Professor in the University of Shizuoka School of Pharmaceutical Sciences from 1987 to 1991, as Associated Professor in the University of Shizuoka's Graduate School of Nutritional Sciences from 1991 to 1993, and a Professor at the University of Shizuoka Graduate School of Nutritional Sciences from 1993 to 2007. In 2007, Yamaguchi was invited as Visiting Professor to the Emory University School of Medicine in Atlanta, Georgia, United States, at the Department of Medicine, Division of Endocrinology and Metabolism and Lipids, where he worked until 2011. He received permanent residence in the United States in 2011. He collaborated as a Visiting Professor at the Baylor College of Medicine, Department of Medicine from 2012 to 2013, in Houston. Yamaguchi was appointed adjunct professor at Emory in the Department of Hematology and Medical Oncology from 2013 to 2016, and a visiting professor at the School of Medicine, University of California at Los Angeles (UCLA).

Present Position:  Professor, Cancer Biology Program, University of Hawaii Cancer Center,
University of Hawaii at Manoa, Honolulu, USA.

Founding Director, The Regucalcin Biomedical Institute, Shizuoka, Japan.

Education:

April 1, 1967  Shizuoka College of Pharmacy, B.S.  Pharmaceutical Sciences (~March 31, 1971)
April 1, 1971  Shizuoka College of Pharmacy, Graduate School of Pharmaceutical Sciences, M.S.  Pharmaceutical Sciences (~March 31, 1973)
April 1, 1973  Shizuoka College of Pharmacy,  Graduate School of Pharmaceutical Sciences, Ph.D.  Pharmaceutical Sciences (~September 28, 1976)

National Qualification:                                                                                                                Pharmacist (Japan, Registered No. 354325, April, 1971; ~ present)
Clinical Inspector (Japan, Registered No. 141855, September, 1971; ~ present)

Principal Positions Held:

April 1, 1973,  Research Associate, Shizuoka College of Pharmacy, Department of Biochemical Toxicology, Shizuoka, Japan (~ March 31, 1986)
July 1, 1981,   Visiting Lecturer, University of Pennsylvania, School of  Medicine, Department of Biochemistry, Philadelphia, PA, USA  (~September 30, 1981)
July 1, 1985,   Visiting Assistant Professor, Texas Tech University, School of Medicine, Department of Pharmacology, Lubbock, TX, USA (~December 30, 1985)
April 1, 1986,  Assistant Professor, Shizuoka College of Pharmacy, Department of Biochemical Toxicology, Shizuoka, Japan (~March 31, 1987)
April 1, 1987,   Assistant Professor, University of Shizuoka, School of Pharmaceutical Sciences, Department of Biochemistry and Toxicology, Shizuoka, Japan (~March 31, 1991)
August 1, 1988,   Visiting Assistant Professor, The University of Texas, Medical School at Houston, Department of Physiology and Cell Biology, Houston, TX, USA (~October 30, 1988)
April 1, 1991,    Associate Professor, University of Shizuoka, Graduate School of Nutritional Sciences, Laboratory of Endocrinology and Molecular Metabolism, Shizuoka, Japan (~May 31, 1993) 
June 1, 1993,     Professor, University of Shizuoka, Graduate School of Nutritional Sciences, Laboratory of Endocrinology and Molecular Metabolism, Shizuoka, Japan (~ August 31, 2007)
November 1, 2007,   Visiting Professor, Emory University School of Medicine, Department of Medicine, Division of Endocrinology  and Metabolism and Lipids, Atlanta, GA, USA (~ October 31, 2011)
November 1, 2011,   Visiting Professor, The University of Georgia, College of Family and Consumer Sciences, Department of Foods and Nutrition, Athens, GA,  USA (~ August 31, 2012
April 15, 2012,   Visiting Professor, The University of Missouri-Columbia, College of Veterinary Medicine, Department of Veterinary Pathobiology, Columbia, MO, USA  (~ October 31, 2012)
September 1, 2012,   Visiting Professor, Baylor College of Medicine, Department of Medicine, Division of Diabetes, Endocrinology and Metabolism, Houston, TX, USA (~ April 30, 2013)
May 15, 2013,   Adjunct Professor, Emory University School of Medicine, Department of Hematology and Medical Oncology, Atlanta, GA, USA (~ August 29, 2016)
January 30, 2017,   Adjunct Professor, Cancer Biology Program, University of Hawaii Cancer Center, University of Hawaii  at Manoa, Honolulu, HI, USA (~ May 31, 2017)
May 15, 2017,   Visiting Professor, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles (UCLA), CA, USA (~ June 30, 2019)
July 1, 2019,    Adjunct Professor, Cancer Biology Program, University of Hawaii Cancer Center,  University of Hawaii at Manoa (~ February 29, 2020)
March 1, 2020,     Professor, Cancer Biology Program, University of Hawaii Cancer Center, University of Hawaii at Manoa (~ present)

Additional Positions Held:

June 2004    Deputy Director General, The International Biographical Centre  (Cambridge,  England)（~ present）
April 2004    Lifetime Deputy Governor, The American Biographical Institute Research Association  (Raleigh, USA)（~ present）
April 2007    Scientific Advisor, Primus Pharmaceutical Inc. (Scottsdale, USA)  (~ present)
March 2015   Scientific Advisor, Bone Health Nutrient Laboratories Inc..  (Tokyo, Japan) (~April, 2022)
April 2016,   Scientific Advisor, Nac Co., Ltd. (Tokyo, Japan)（~ present）
September 2016  Founding Director, The Regucalcin Biomedical Institute  (Shizuoka, Japan) (~ present)                                                                                                                                                                                                               

Editorial Board Members (International Journals):

 1  January, 200l     Editorial Academy Member in International Journal of Molecular Medicine (~ September, 2019)
 2  April 2002      Editor in the Biomedical Research on Trace Elements  (~ July, 2008)
 3  January 2009    Editorial Board Member in Molecular Medicine Reports  (~ September, 2019)
 4  April 2009      Editorial Board Member in Journal of Osteoporosis  (~ September 2016)
 5  August 2009    Editorial Board Member in the International Journal of Medical and Medical Sciences (~ August, 2012)
 6  January 2010   Editorial Board Member in the Journal of Diabetes and Endocrinology (~December, 2012)
 7  April 2010      Editorial Board Member in World Journal of Orthopedics (~ March, 2012)
 8  May 2010       Editor in Biotechnology Research International (~ December, 2013 )
 9  June 2010       Editor in Journal of Diabetes and Metabolism (~June, 2012)
10  July 2010       Editorial Board Member in the Molecular and Cellular Biochemistry  (~ November 30, 2013)
11  September 2010  Editorial Board Member in Endocrinology Studies (~August, 2012)
12  October 2010    Editorial Board Member in Experimental and Therapeutic Medicine (~September, 2019)
13  February 2011   Editorial Board Member in Alternative Medicine Studies (~ December, 2014)
14  March 2011     Editorial Board Member in Stem Cell Discovery (~ December, 2019)
15  April 2011      Editor-in-Chief in Endocrinology & Metabolic Syndrome (~ December, 2019)
16  October 2011    Executive Editor in Journal of Obesity & Weight Loss  Therapy  (~ September, 2016)
17  November 2011   Editorial Board Member in Internal Medicine (~ September, 2016)
18  November 2011   Executive Editor in Journal of Nutrition & Food Sciences (~ August, 2016)
19  January 2012     Executive Editor in Journal of Nutritional Disorders & Therapy (~August, 2016)
20  April  2012       Editorial Board Member in Biomedical Reports (~September, 2019)
21  September 2012   Editorial Board Member in Research and Reports  in Biochemistry (~August, 2015)
22  October 2012    Editorial Board Member in the International Journal of Food Science, Nutrition and Dietetics (~ September, 2016)
23  November  2012   Editor-in-Chief in OA Biotechnology (~ January, 2015)
24  November 2012   Executive Editor in OA Biochemistry (~ January, 2015)
25  December 2012   Editorial Board Member in General Medicine (~ September, 2016)
26  December  2012   Executive Editor in Vitamins & Minerals (~August, 2016)
27  December 2012   Editorial Board Member in the International Journal of Physical  Medicine & Rehabilitation (~ September, 2016)
28  December 2012   Editor-in-Chief in Hormonal Studies (~ present)
29  January 2013     Editorial Board Member in OA Diabetes (~ January 2015)
30  February  2013   Academic Editor in the British Journal of Pharmac Research  (~ December, 2015)
31  June 2013       Editor-in-Chief in Biochemistry & Physiology (~August, 2016)
32  June  2013       Editor-in-Chief in Journal of Molecular and Genetic  Medicine (~ August, 2016)
33  July 2013       Editorial Board Member in Editorial Board Member in JSM Cell & Developmental   Biology (~ June, 2016)
34  July 2013       Executive Editor in Journal of Research and Development (~ August, 2016)
35  July 2013       Editor-in-Chief in Journal of Osteoporosis and Physical Activity (~ August, 2016)
36  September 2013  Editorial Board Member in Journal of Bone Marrow Research (~ August 2016)
37  September 2013  Editorial Board Member in Journal of Exercise, Sports & Orthopedics  (~ August, 2016)
38  October 2013    Editor-in-Chief in Edorium Journal of Nutrition and Dietetics  (~ December, 2017)
39  October 2013    Editorial Board Member in the Austin Journal of Endocrinology and Diabetes (~ September, 2016)
40  October 2013    Editorial Board Member in Cancer Science & Research: Open Access   (~ September, 2017)
41  November 2013  Editorial Board Member in the International Journal of Diabetology & Vascular Disease Research  (~ December, 2016)
42  November 2013  Editorial Board Member in the International Journal of Medical  Biotechnology & Genetics (~ December, 2016)
43  November 2013  Editorial Board Member in Journal of Clinical & Experimental Oncology (~ October, 2016)
44  November 2013   Editorial Board Member in Obesity & Control Therapies Open Access (~ October, 2017)
45  November 2013  Editorial Board Member in the Organization of Public Integrity & Ethics (PIE)     (United Kingdom), appointed as PIE Editor-in-Chief 
46  January  2014    Editorial Board Member in World Journal of Biological Chemistry (~ December, 2016)
47  January 2014     Editorial Board Member in Journal of Cancer Science & Therapy  (~ September, 2016)
48  April 2014      Editorial Board Member in the Austin Journal of Medical Oncology  (~ March, 2017)
49  April 2014      Editorial Board Member in the Journal of Stem Cell Research and Transportation (~ March 2016)
50  April 2014      Editorial Board Member in the Journal of Diabetes and Metabolic Syndrome Disorder (~ August, 2016)
51  April 2014      Editorial Board Member in Journal of Cancer Prevention &  Current Research (~ March, 2017)
52  May 2014       Editorial Board Member in Journal of Diabetes, Metabolic Disorders & Control (~ May, 2017)
53  May 2014       Editorial Board Member in Hematology, Blood Transfusion and Disorders  (~ April, 2016) 
54  May 2014       Editorial Board Member in the International Journal of Medical Biotechnology & Genetics (~ December, 2016) 
55  June 2014      Editor-in-Chief in the International Journal of Diabetes & Clinical  Diagnosis (~August, 2016)
56  June 2014      Editorial Board Member in Journal of Endocrine Disorders (~ May, 2017)
57  July 2014       Editor-in-Chief in the International Journal of Diabetes and Clinical Research (~ February, 2021)
58  July 2014       Founding Editor-in-Chief in Integrative Molecular Medicine  (~ May, 2016)
59  July 2014       Founding Editor-in-Chief in Integrative Cancer Science and Therapeutics  (~ May 2016)
60  July 2014       Founding Editor-in-Chief in Integrative Obesity and Diabetes (~ March, 2016)
61  July 2014       Founding Editor-in-Chief in Integrative Food, Nutrition and  Metabolism  (~ March, 2016)
62  September 2014    Editorial Board Member in Journal of International Research in Medical and    Pharmaceutical Sciences (~ August, 2017)
63  October 2014      Editorial Board Member in Austin Journal of Clinical Medicine  (~ September, 2017)
64  October 2014     Editorial Board Member in Annals of Nutritional Disorder &  Therapy  (~ September, 2017)
65  October 2014     Editorial Board Member in Hepatoma Research (~ December, 2016)
66  November 2014   Editorial Board Member in Journal of Obesity and Overweight  (~ September, 2017)
67  November 2014   Editorial Board Member in Journal of Clinical and  Experimental Genetics  (~ September, 2017)
68  December 2014   Editorial Board Member in International Journal of Cardiology and Research (~September, 2017)
69  December 2014   Editor-in-Chief in Edorium Journal of Nutrition and Dietetic (~ November, 2017)
70  January 2015    Editorial Board Member in Clinical Medical Reviews and Case  Reports  (~ December, 2018)
71  January 2015   Editorial Board Member in International Archives of Urology  and Complications (~ December, 2016)
72  January 2015   Editorial Board Member in HSOA Journal of Orthopedic Research  & Physiotherapy (~ January, 2018)
73  February 2015  Editorial Board Member in SM Journal of Food and Nutritional Disorders   (~ January, 2018)
74.  February, 2015  Editorial Board Member in the International Archives of Clinical Pharm (~ January, 2018)
75  February 2015  Editorial Board Member in the International Journal of  Endocrinology and Metabolic Disorders (~ September, 2018)
76  March 2015    Founder and Editor-in-Chief of the Journal of Cancer Biology and Therapeutics   (~ June, 2016)
77  March 2015    Founder and Editor in Chief of Integrative Biomedical Sciences (~ June, 2016)
78  March 2015    Founder and Editor-in-Chief of the Journal of Bone  Biology and Osteoporosis (~ June, 2016)
79  April 2015     Academic Editor in the British Journal of Medicine and Medical  Research  (~ September, 2017)
80  August 2015   Editorial Academy Member in International Journal of Oncology   (~September, 2019)
81  January 2017   Advisory Committee of Edorium Journals (India)  (~ December, 2018)
82  February 2017  Editorial Board Member in Annals of Nutrition and Food  Science  (~ December, 2018)
83  February 2017  Editorial Board Member in the Journal of Hematology and Serology  (~December, 2019)
84  May 2017         Editorial Board Member in Journal of Comprehensive Cancer  Research  (~ December, 2019)
85  March 2017      Editor-in-Chief in Cancer Studies (~ September, 2019)
86  March 2017      Editor-in-Chief in Physical Medicine and Rehabilitation (~ December 2018)
87  June 2017         Editor-in-Chief in Journal of Integrative Food Sciences & Nutrition  (~ September 2019)
88  January 2018     Editor-in-Chief in Endocrinology, Diabetes and Obesity (~ December 2018)
89  October 2019    Section Editor in the Editorial Board of Current Nutraceuticals  (~ present)
90  December 2019  Editorial Advisory Board Member of Current Molecular Medicine (-  present)  91  March 2020        Editorial Board Member of Cancers (~ present)                                                     92  January 2021      Co-Editor-in-Chief, Editorial Board Member of Current Cancer Drug Targets (~ present)                                                                                                                                                93  January 2021     Editorial Board Member of Translational Oncology (~ present)                          94  June 2022          Editorial Board Member (Editor) Discover Oncology (- present)   95 January 2022     Editorial Board Membt (Editor) in Nutraceuticals (~ present)                                                            96 January 2023     Founding  Editor-in-Chief in Current Cell Science (- present)                                  97 November 2023  Editorial Board Member in Disease & Research (~ present)                                98 January 2024     Editorial Board Member (Editor) in Current Oncology (~ present)                          99 April 2024   Editorial Board Member in Tumor Discover (~ present)                                                100 April 2024    Editorial Board Member in World Journal of Oncology (~ present)                                                                                                                                                  

Membership in Professional Organizations:

April, 1971     Japan Society for Pharmaceutical Sciences (~ December, 2011)
April, 1973     Japan Society for Biochemistry, Councilor (~ December, 2011)
April, 1977     Endocrine Society for Japan, Councilor (~ March, 2010)
January, 1984   International Society of Bone and Mineral (~ December, 2007)
April, 1987     Japan Society for Pharmacology, Councilor (~ December, 2007)
April, 1988     Japan Society for Bone and Mineral Metabolism,  Councilor (~ March, 2010)
April, 1990     Japan Society for Biomedical Research on Trace Elements, Councilor (~ March, 2011)
June, 1995      Japan Society for Hepatocyte Research, Councilor  (~June, 2006)
January, 1996   New York Academy of Sciences (~ December, 2012)
January, 1997   European Society of Calcium (~December, 2004) 
April,  1999    Japan Society for Osteoporosis, Councilor (~ December, 2008)
January, 2001   American Society for Cell Biology (~ December, 2007)
January, 1999   American Society for Bone and Mineral Research (~ December, 2016)
January, 2005   American Society for Biochemistry and Molecular Biology  (~ present)
January, 2021   The European Union (EU) Academy of Sciences (~ March, 2023)                      December, 2022, Full member in Sigma Xi, The Scientific Research Honor Society (USA) (~ present)

Awards and Honors:

 1  July 1981    「Award for Academy Encouragement in Tokai Branch of Pharmaceutical Society of Japan」
 2  October 1987 「Bounty of Takeda Science Promotion Foundation 」 (Japan)
 3  March 1992    「Prize for Sato Memorial Foundation 」 (Japan)
 4  May 1992       「Saito Prize of Chion Party」(Japan)
 5  March 1994    「Bounty of Encouragement Fundation in Pharmaceutical Research」(Japan)
 6  October 1999  「Award of Mishima Kaiun Memorial Foundation」(Japan) 
 7  October 2004  「Bounty of the Yamanouchi Foundation for Research on Metabolic Disorders」 (Japan)
 8 May 2004 「International Scientist of the Year 2004」(The International Biographical  Centre of Cambridge, England)
 9  August 2004   「The IBC Lifetime Achievement Award」(The International Biographical Centre of Cambridge, England)
10  December 2004 「The World Lifetime Achievement Award」(The American Biographical  Institute, Inc., Raleigh, USA) 
11 July 2004  「The Outstanding Professional Award」 (The American Biographical Institute,  Inc., Raleigh, USA) 
12 September 2004 「The International Order of Merit」  (The International Biographical Centre of  Cambridge, England) 
13 September 2004 「The IBC Hall of Fame」 (The International Biographical Centre of Cambridge, England) 
14 October 2004  「The American Hall of Fame」 (The American Biographical Institute, Inc., Raleigh, USA) 
15  May 2005  「Lifetime Achievement Award」 (The World Congress of  Arts, Sciences and Communications, Cambridge (England) 
16  May 2005  「Lifetime Achievement Award 2005」(The United Cultural Convention, Raleigh,  USA) 
17 September 2005 「The Founder of American Order of Excellence」(The American Biographical Institute, Inc., Raleigh, USA) 
18  March, 2006  「Senji Miyata Foundation Award 2005」(Japan)
19  April, 2006  「The IBC’s Salute to Greatness Award」 (International Biographical Centre, Cambridge, England) 
20  July 2006 「The American Medal of Honor Award」(American Biographical Institute, Inc., Raleigh, USA) 
21  July 2007 「Award of the Japan Society for Biomedical Research on Trace Elements 2007」 (Japan)
22  January 2007   「The Distinguished Service to Science Award」 (International Biographical Centre, Cambridge, England) 
23 February 2008  「Gold Medal for Japan」(American Biographical Institute, Inc.,  Raleigh, USA) 
24  March  2016    「It’s The Journey Award」(It’s The Journey Inc., Atlanta, USA) 
25  July  2017   「The 2017 Albert Nelson Marquis Lifetime Achievement Award」（Marquis Who's Who, USA）                                                                                                                                            26 March 2022   「Distinguished Scientist Award 」 in The International Scientist Awards on Engineering, Science, and Medicine Organized by VDGOOD Professional  Association, India              27 December 2022  Full Membership in SIGMA XI (The Scientific Research Honor Society, USA)

Registered patents:

 1.  Osteogenesis promoter
     United State Patent.  Patent Number: 5294634 
     Registered: March 15, 1994
     Inventor:  Masayoshi Yamaguchi (Japan)
     Assignee: Zeria Pharmaceutical Co., Ltd. (Japan) Hamari Chemicals Co., Ltd. (Japan)

 2.  Osteogenesis promoter
      European Patent.  Patent Number: 0495106 
       Registered: December 6, 1995
       Inventor:  Masayoshi Yamaguchi (Japan)
       Assignee: Zeria Pharmaceutical Co., Ltd. (Japan) Hamari Chemicals Co., Ltd. (Japan)

 3.  Osteogenesis promoter
       Korean Patent.  Patent Number: 147855 
       Registered: May 20, 1998
       Inventor:  Masayoshi Yamaguchi (Japan)
       Assignee: Zeria Pharmaceutical Co., Ltd. (Japan)  Hamari Chemicals Co., Ltd. (Japan)

 4.  Osteogenesis promoter
      Japan Patent.  Patent Number: 2811331 
      Registered: August 7, 1998
      Inventor:  Masayoshi Yamaguchi (Japan)
      Assignee: Zeria Pharmaceutical Co., Ltd. (Japan)  Hamari Chemicals Co., Ltd. (Japan)

5. Osteogenesis promoter.  
    Canadian Patent.  Patent Number: 2,067,374 
    Registered: July 4, 2000
    Inventor: Masayoshi Yamaguchi 
    Assignee: Zeria Pharmaceutical Co., Ltd. (Japan) Hamari Chemicals Co., Ltd. (Japan)

6.  Composition for stimulating bone mass and preventing osteoporosis.
    Japan Patent.  Patent Number: 3,005,794 
    Registered: November 2, 1999
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Masayoshi Yamaguchi (Japan)

7.  Composition for stimulating osteogenesis and preventing reduction of bone salt.  
     United States Patent. Patent Number: 5,935,996 
     Registered: August 10, 1999
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Masayoshi Yamaguchi (Japan)

 8.  Composition for preventing osteoporosis
     Japan Patent.  Patent Number: 3,459,932 
     Registered: August 15, 1999
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Honen Corporation Co. Ltd. (Japan)

 9.  Bone-strengthening agents, food compositions for strengthening bone 
      and feed compositions for strengthening.
      United States Patent.  Patent Number: US6,806,252 B2
      Registered:  October 19, 2004
      Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Meiji Seika Kaisha, Ltd. (Japan)

10.  Composition for preventing osteoporosis.
      Japan Patent.  Patent Number: 3,749,978
      Registered: December 16, 2005
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Masayoshi Yamaguchi (Japan)

11.  Model animal with overexpression of regucalcin
      Korean Patent. Patent Number:  0611804  
      Registered: August 4, 2006 
      Inventor:  Masayoshi Yamaguchi (Japan)
      Assignee: Japan Science and Technology Agency

12.  Osteogenesis promotor containing β-cryptoxanthin as the Active Ingrediant
      Japan Patent.  Patent Number: 3,892,014 
      Registered: December 16, 2006
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Ehime Beverage Co. Ltd. (Japan)

13.  Soybean foods for stimulating osteogenesis and preventing reduction of 
      bone salt.  
      Japan Patent.  Patent Number: 3,923,052 
      Registered: March 2, 2007
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Taishi Food Co. Ltd. (Japan) 

14.  Model animal with overexpression of regucalcin
      Japan Patent.  Patent Number: 3,949,520 
      Registered: April 27, 2007
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Japan Science and Technology Agency (Japan)

 15. Drug for treating bone disorder 
      Japan Patent.  Patent Number: 3,974,213
      Registered: June 22, 2007
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Nipro Co. Ltd. (Japan) 

16.  Functional foods for preventing and treatment diabetic osteoporosis and diabetes
     Japan Patent.  Patent Number: 4,023,680 
     Registered: June 4, 2007
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Masayoshi Yamaguchi (Japan)

17.  Model animal with overexpression of regucalcin
     United States Patent.  Patent Number: 7,355,093 B2 
     Registered: April 8, 2008
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Japan Science and Technology Agency (Japan)

18.  Model animal with hyperlipidemia and hyperalbuminemia
     Korean Patent.  Patent Number: 10-2006-7008816 
     Registered: June 16, 2008
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Japan Science and Technology Agency (Japan)

19.  Rat model with overexpression of regucalcin
     European Patent. Patent Number 1437043  
     (England, France, Deutch, Switherland, Italy, Netherland). 
      Registered:  January 5, 2011 
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Japan Science and Technology Agency (Japan)

20.  Osteogenesis promotor containing β-cryptoxanthin as the active ingrediant
     USA Patent. Patent Number US8148431B2 
     Registered:  April 3, 2012
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Kemin Foods, L.C.

21.  Methods for treating inflamatory conditions and states, and cancers by 
     antagonizing NF-kb Activation
     USA Patent Number US 9301945 B2
     Registered: April 5, 2016,  Expire: October 5, 2032
     Inventor: M. Neale Weitzmann, Masayoshi Yamaguchi:
     Assignee: Emory University: Office of Technology Transfer

22.  NF-κB Inhibitor.
      Japan Patent:  Patent Number: P5950656
      Registered: June 17, 2016
      Inventor: Masayoshi Yamaguchi (Japan)
      Assignee: Maruhachi Muramatsu, Inc. (Japan)

23.  Method for suppressing proliferation and/or inducing apoptosis of cancer cells.
     USA Patent Number: US 9937216 B2
     Registered: April 10, 2018   
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Maruhachi Muramatu, Inc. (Japan)

24.  Methods for suppressing of adipogenesis
     Japan Patent Number: P6360357
     Registered: April 29, 2018
     Inventor: Masayoshi Yamaguchi:
     Assignee: Maruhachi Muramatu, Inc. (Japan)

25.  Therapeutic combination of sesquiterpenes and flavonoids 
     USA Patent No.,  US 10,3000,040 B2
     Date of patent: May 28, 2019
     Inventor: Masayoshi Yamaguchi (Japan)
    Assignee: Primus Pharmaceutical Inc. (USA)

26.  Method for treating disease associated with transcription activation by NF-κB. 
     United State Patent:  Patent Number: US10,4963,705 B2
     Registered: November 5, 2019
     Inventor: Masayoshi Yamaguchi (Japan)
     Assignee: Maruhachi Muramatsu, Inc. (Japan)

27.  Methods and formulations for supporting and promoting bone health.
    USA Patent No. US 10456365 B2  
    Date of patent: October 29, 2019
     Inventor: Masayoshi Yamaguchi (Japan)
    Assignee: Primus Pharmaceutical Inc. (USA)

Listed in International Biographical Books                                                                                                                                                                                                                                                                                                                                                                                                                      1. 「Who’sWho in the World」 (Marquis Who’sWho 21st Century Editions,  New Providence, USA)          (22nd Edition, 2005 ~ 32nd Edition, 2015; 37nd Edition, 2020) 

2. 「Who’sWho in Science and Engineering」 (Marquis Who’sWho 21st 
      Century Editions, New Providence, USA (2003-2004, 7th Edition ~)

3. 「Who’sWho in America」 (Marquis Who’sWho 21st Century Editions, 
      New Providence, USA) (63rd Edition 2009~)

4.  「Who’sWho in Asia」(Marquis Who’sWho 21st Century Editions, 
      New Providence, USA) (2007, 1th Edition; 2012, 2nd Edition ~)

 5. 「The Definitive Book of Deputy Director Generals」 (The International 
      Biographical Centre, Cambridge, England)（2005）

 6. 「The Cambridge Blue Book」　 (The International Biographical Centre, 
       Cambridge, England) （2005/2006）

 7. 「Dictionary of International Biography」(The International Biographical 
      Centre, Cambridge, England) （2007, 2008, 2009, 2010 ~）

  8. 「2000 Outstanding Intellectuals of the 21st Century」 (The International Biographical Centre      of  Cambridge, England) (2007 Fourth Edition, 2008 Fifth Edition ~)

  9. 「2000 Outstanding Scientists」 (The International Biographical Centre of Cambridge, England)   (2008/2009 Edition)

 10. 「Great Lives of the 21st Century」(The International Biographical Centre of Cambridge,             England) (2007 First Edition ~)

 11. 「Great Minds of the 21st Century」 (The American Biographical Institute,  Inc., Raleigh, USA)     (2005 Edition, 2006/2007 Edition, 2008/2009 Edition, 2010/2011 Fifth Edition ~)

 12. 「500 Greatest Geniuses of the 21st Century」 (The American Biographical  Institute, Inc.,  Raleigh, USA) (2006, Edition)

Publications:

ORCID iD number; 0000-0002-8511-110X

Google Scholar:                                                                                           https://scholar.google.com/citations?user=PG8yrnkAAAAJ&hl=ja

 NIH My Bibliography (PubMed):                                                                  https://www.ncbi.nlm.nih.gov/myncbi/1L9LjwyhgyyYWQ/bibliography/public/

Original Papers (Peer-reviewed)

  1.  Masayoshi Yamaguchi, Takeo Yamamoto:
      Effect of thyrocalcitonin and actinomycin D on the calcium concentration of
      serum and liver in rats treated with lead.
      Toxicology and Applied Pharmacology, 29: 223-228 (1974).
  2. Takeo Yamamoto, Masayoshi Yamaguchi, Yasunobu Suketa:
      Calcium accumulation in liver and calcium mobilization in bone of 
      lead-poisoned rats.
     Toxicology and Applied Pharmacology, 27: 204-205 (1974).
  3.  Masayoshi Yamaguchi, Hideji Sato, Takeo Yamamoto:
      The increase of acid hydrolases activity in bone tissue of rats treated with lead acetate.
      Chemical & Pharmaceutical Bulletin, 23: 1789-1792 (1975).
  4. Masayoshi Yamaguchi, Takeo Yamamoto:
      Effect of thyroparathyroidectomy and tryrocalcitonin on the bone acid
      phosphatase activity and the serum calcium concentration in rats treated with  lead acetate.
       Chemical & Pharmacential Bulletin, 23: 1882-1884 (1975).
  5. Masayoshi Yamaguchi, Yuko Takei, Takeo Yamamoto:
      Effect of tryrocalcitonin on calcium concentration in liver of intact and 
      tryroparathyroidectomized rats.
      Endocrinology, 96: 1004-1008 (1975).
  6. Masayoshi Yamaguchi, Takeo Yamamoto:
      Binding of calcium by the soluble fraction from normal rat liver.
      Chemical & Pharmaceutical Bulletin, 23: 2418-2421 (1975).
   7.  Other publications are over 600.