Per Morten Sandset

Per Morten Sandset (born 30 June 1956) is a Norwegian doctor. He is a professor of medicine at the University of Oslo and was appointed Vice-Chancellor of the University on 1 August 2017.
Sandset received his doctorate in medicine in 1989 at the University of Oslo with the dissertation Studies on Tissue Factor Pathway Inhibitor . He has had research stays in San Diego, USA, and in Florence, Italy. He is a specialist in general internal medicine and blood diseases and has been Professor II in medicine in the field of thrombosis research at the University of Oslo since 2002.
He has previously been head of the Department of Hematology at Ullevål University Hospital (2002–2010), head of research at the Cancer, Surgery and Transplant Clinic and section chief at the Department of Blood Diseases at Oslo University Hospital (from 2010) and director of research, innovation and education at Helse Sør. -East from 2015 to 2017.
After Svein Stølen and Gro Bjørnerud Mo won the election of Rector and Vice-Rector at the University of Oslo in April 2017, Sandset was appointed Vice-Rector for Research and Innovation on 1 August 2017.
Sandset has been editor-in-chief of the international journal Thrombosis Research in the period 2002-2016.

Background

Medical degree at UiO 1981 and doctorate in medicine at UiO in 1989
Specialist in Internal Medicine in 1993 and in Blood Diseases in 2002
1989-90 Post.doc. at UCSD Medical Center, San Diego, California (with Prof. Samuel I Rapaport)
1993-2010 Section chief physician and head of the haematological research laboratory at Ullevål University Hospital
2002-2010 chief physician / head of the hematology department
2002-2006 assistant division director in the medical division, and in 2008 the division director was appointed at the same place
2002-2017 Professor II at the University of Oslo (thrombosis research)
2010-2015 research leader in the Department of Cancer, Surgery and Transplantation at Oslo University Hospital (OUS)
2015-2017 Director of Research, Innovation and Education in Health South-East - secondment as section chief physician at OUS
From 2017 assistant position as chief physician / researcher at OUS

Academic Interests

Clinical focus has been on the diagnosis, prevention and treatment of venous thrombosis and stroke. This especially applies to optimal antithrombotic treatment.

Research focus has been:
Mechanisms for how blood clotting (= coagulation system) is started and regulated - especially the importance of the regulator protein "tissue factor pathway inhibitor = TFPI" . Includes cell and molecular biology studies, animal experimental studies and clinical studies (translation research). In recent years, we have been particularly interested in the connection between hemostasis and apoptosis, angiogenesis and cell growth.

Thrombosis related to hormone use and related to pregnancy, especially related to mechanisms of thrombosis. Includes epidemiological approach ("Venous Thromboembolism in Pregnancy Study = VIP") and clinical, randomized trials ("Estrogen in Venous Thromboembolism Study = EVTET" and "Raloxifene, Estrogen and Tibolone Study = RET").

Diagnosis and treatment of venous thrombosis. Mainly responsible for the first randomized study on catheter-directed thrombolytic therapy in severe deep vein thrombosis ("CaVenT study"). Has been instrumental in testing new anticoagulant drugs for the treatment of venous thrombosis

Treatment of acute stroke - especially the importance of anticoagulation therapy and anticoagulant therapy (thrombolysis). Mainly responsible for "Heparin in acute embolic stroke trial = HAEST" and involved in several major international stroke studies.

Publications:

Publications 2021
Bøhn SK, Thune I, Flote VG, Frydenberg H, Bertheussen GF, Husøy A, Fjeldheim F, Brunvoll SH, Hjartåker A, Mowinckel MC, Sandset PM, Iversen PO (2021)
Effects of a 1-Year Physical Activity Intervention on Markers of Hemostasis among Breast Cancer Survivors: A Randomized Controlled Trial
TH Open, 5 (1), e14-e23
DOI 10.1055/s-0040-1721782, PubMed 33564742

Cui XY, Tjønnfjord GE, Kanse SM, Dahm AEA, Iversen N, Myklebust CF, Sun L, Jiang ZX, Ueland T, Campbell JJ, Ho M, Sandset PM (2021)
Tissue factor pathway inhibitor upregulates CXCR7 expression and enhances CXCL12-mediated migration in chronic lymphocytic leukemia
Sci Rep, 11 (1), 5127
DOI 10.1038/s41598-021-84695-8, PubMed 33664415

Engeseth M, Enden T, Sandset PM, Wik HS (2021)
Predictors of long-term post-thrombotic syndrome following high proximal deep vein thrombosis: a cross-sectional study
Thromb J, 19 (1), 3
DOI 10.1186/s12959-020-00253-8, PubMed 33419441

Khialani D, Vasan S, Cushman M, Dahm AEA, Sandset PM, Rossouw J, van Hylckama Vlieg A (2021)
Venous thrombosis with oral postmenopausal hormone therapy: Roles of activated protein C resistance and tissue factor pathway inhibitor
J Thromb Haemost (in press)
DOI 10.1111/jth.15319, PubMed 33774921

Publications 2020

Andersen NG, Mowinckel MC, Sunde K, Sandset PM, Beitland S (2020)
Utility of coagulation analyses to assess thromboprophylaxis with dalteparin in intensive care unit patients
Acta Anaesthesiol Scand, 65 (4), 489-498
DOI 10.1111/aas.13748, PubMed 33205407

Andresen MS, Stavik B, Sletten M, Tinholt M, Sandset PM, Iversen N, Skretting G (2020)
Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells
Sci Rep, 10 (1), 4036
DOI 10.1038/s41598-020-61018-x, PubMed 32132611

Godolphin PJ, Bath PM, Partlett C, Berge E, Brown MM, Eliasziw M, Sandset PM, Serena J, Montgomery AA (2020)
Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification
Eur Stroke J, 5 (2), 174-183
DOI 10.1177/2396987320910047, PubMed 32637651

Hannevik TL, Brekke J, Enden T, Frøen H, Garresori H, Jacobsen EM, Paulsen PQ, Porojnicu AC, Ree AH, Torfoss D, Velle EO, Wik HS, Ghanima W, Sandset PM, Dahm AEA (2020)
Thrombosis and bleedings in a cohort of cancer patients treated with apixaban for venous thromboembolism
Thromb Res, 196, 238-244
DOI 10.1016/j.thromres.2020.08.042, PubMed 32919178

Kakkos SK, Gohel M, Baekgaard N, Bauersachs R, Bellmunt-Montoya S, Black SA, Ten Cate-Hoek AJ, Elalamy I, Enzmann FK, Geroulakos G, Gottsäter A, Hunt BJ, Mansilha A, Nicolaides AN, Sandset PM, Stansby G, Esvs Guidelines Committee, de Borst GJ, Bastos Gonçalves F, Chakfé N, Hinchliffe R, Kolh P, Koncar I, Lindholt JS, Tulamo R et al. (2020)
Editor's Choice - European Society for Vascular Surgery (ESVS) 2021 Clinical Practice Guidelines on the Management of Venous Thrombosis
Eur J Vasc Endovasc Surg, 61 (1), 9-82
DOI 10.1016/j.ejvs.2020.09.023, PubMed 33334670

Thorsen L, Haugnes HS, Fosså SD, Brydøy M, Tandstad T, Wisløff T, Gjerset GM, Edvardsen E, Larsen KO, Sandset PM, Henriksson CE, Raastad T, Negaard HFS (2020)
Thromboembolic events after high-intensity training during cisplatin-based chemotherapy for testicular cancer: Case reports and review of the literature
Int J Cancer, 147 (11), 3189-3198
DOI 10.1002/ijc.33151, PubMed 32525564

Tinholt M, Stavik B, Tekpli X, Garred Ø, Borgen E, Kristensen V, Sahlberg KK, Sandset PM, Iversen N (2020)
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104

Tritschler T, Mathieu ME, Skeith L, Rodger M, Middeldorp S, Brighton T, Sandset PM, Kahn SR, Angus DC, Blondon M, Bonten MJ, Cattaneo M, Cushman M, Derde LPG, DeSancho MT, Diehl JL, Goligher E, Jilma B, Jüni P, Lawler PR, Marietta M, Marshall JC, McArthur C, Miranda CH, Mirault T et al. (2020)
Anticoagulant interventions in hospitalized patients with COVID-19: A scoping review of randomized controlled trials and call for international collaboration
J Thromb Haemost, 18 (11), 2958-2967
DOI 10.1111/jth.15094, PubMed 32888372

Publications 2019

Andersen E, Chollet ME, Baroni M, Pinotti M, Bernardi F, Skarpen E, Sandset PM, Skretting G (2019)
The effect of the chemical chaperone 4-phenylbutyrate on secretion and activity of the p.Q160R missense variant of coagulation factor FVII
Cell Biosci, 9, 69
DOI 10.1186/s13578-019-0333-8, PubMed 31467667

Beitland S, Wimmer H, Lorentsen T, Jacobsen D, Draegni T, Brunborg C, Kløw NE, Sandset PM, Sunde K (2019)
Venous thromboembolism in the critically ill: A prospective observational study of occurrence, risk factors and outcome
Acta Anaesthesiol Scand, 63 (5), 630-638
DOI 10.1111/aas.13316, PubMed 30623406

Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM (2019)
Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
Thromb Haemost, 119 (9), 1481-1488
DOI 10.1055/s-0039-1692426, PubMed 31254974

Eilertsen AL, Dahm AEA, Høibraaten E, Lofthus CM, Mowinckel MC, Sandset PM (2019)
Relationship between sex hormone binding globulin and blood coagulation in women on postmenopausal hormone treatment
Blood Coagul Fibrinolysis, 30 (1), 17-23
DOI 10.1097/MBC.0000000000000784, PubMed 30507711

Engeseth M, Enden T, Andersen MH, Sandset PM, Wik HS (2019)
Does the Villalta scale capture the essence of postthrombotic syndrome? A qualitative study of patient experience and expert opinion
J Thromb Haemost, 17 (10), 1707-1714
DOI 10.1111/jth.14557, PubMed 31265193

Engeseth M, Enden T, Sandset PM, Wik HS (2019)
Limitations of the Villalta scale in diagnosing post-thrombotic syndrome
Thromb Res, 184, 62-66
DOI 10.1016/j.thromres.2019.10.018, PubMed 31707153

Garabet L, Ghanima W, Hellum M, Sandset PM, Bussel JB, Tran H, Henriksson CE (2019)
Increased microvesicle-associated thrombin generation in patients with immune thrombocytopenia after initiation of thrombopoietin receptor agonists
Platelets, 31 (3), 322-328
DOI 10.1080/09537104.2019.1639655, PubMed 31280643

Garabet L, Ghanima W, Rangberg A, Teruel-Montoya R, Martinez C, Lozano ML, Nystrand CF, Bussel JB, Sandset PM, Jonassen CM (2019)
Circulating microRNAs in patients with immune thrombocytopenia before and after treatment with thrombopoietin-receptor agonists
Platelets, 31 (2), 198-205
DOI 10.1080/09537104.2019.1585527, PubMed 30885035

Garabet L, Henriksson CE, Lozano ML, Ghanima W, Bussel J, Brodin E, Fernández-Pérez MP, Martínez C, González-Conejero R, Mowinckel MC, Sandset PM (2019)
Markers of endothelial cell activation and neutrophil extracellular traps are elevated in immune thrombocytopenia but are not enhanced by thrombopoietin receptor agonists
Thromb Res, 185, 119-124
DOI 10.1016/j.thromres.2019.11.031, PubMed 31805421

Godolphin PJ, Bath PM, Algra A, Berge E, Brown MM, Chalmers J, Duley L, Eliasziw M, Gregson J, Greving JP, Hankey GJ, Hosomi N, Johnston SC, Patsko E, Ranta A, Sandset PM, Serena J, Weimar C, Montgomery AA, Adjudicating Outcomes in Stroke Trials Collaboration (2019)
Outcome Assessment by Central Adjudicators Versus Site Investigators in Stroke Trials: A Systematic Review and Meta-Analysis
Stroke, 50 (8), 2187-2196
DOI 10.1161/STROKEAHA.119.025019, PubMed 33755494

Gregersen I, Høibraaten E, Holven KB, Løvdahl L, Ueland T, Mowinckel MC, Dahl TB, Aukrust P, Halvorsen B, Sandset PM (2019)
Effect of hormone replacement therapy on atherogenic lipid profile in postmenopausal women
Thromb Res, 184, 1-7
DOI 10.1016/j.thromres.2019.10.005, PubMed 31677448

Sandset PM (2019)
Inflammation, infection and coagulation disorders
Hemasphere, 3 2, 88

Sandset PM, Dahm AEA (2019)
Is venous thromboembolism a problem in patients with cancer in palliative care?
Lancet Haematol, 6 (2), e61-e62
DOI 10.1016/S2352-3026(18)30218-7, PubMed 30709433

Schultz NH, Holme PA, Henriksson CE, Mowinckel MC, Sandset PM, Bratseth V, Jacobsen EM (2019)
The influence of rivaroxaban on markers of fibrinolysis and endothelial cell activation/injury in patients with venous thrombosis
Thromb Res, 177, 154-156
DOI 10.1016/j.thromres.2019.03.010, PubMed 30903875

Skretting G, Andersen E, Myklebust CF, Sandset PM, Tinholt M, Iversen N, Stavik B (2019)
Transcription factor FOXP3: A repressor of the TFPI gene?
J Cell Biochem, 120 (8), 12924-12936
DOI 10.1002/jcb.28563, PubMed 30861202

Publications 2018

Andersen E, Chollet ME, Myklebust CF, Pinotti M, Bernardi F, Chuansumrit A, Skarpen E, Sandset PM, Skretting G (2018)
Activation of Endoplasmic Reticulum Stress and Unfolded Protein Response in Congenital Factor VII Deficiency
Thromb Haemost, 118 (4), 664-675
DOI 10.1055/s-0038-1637690, PubMed 29618153

Gravensteen IK, Jacobsen EM, Sandset PM, Helgadottir LB, Rådestad I, Sandvik L, Ekeberg Ø (2018)
Anxiety, depression and relationship satisfaction in the pregnancy following stillbirth and after the birth of a live-born baby: a prospective study
BMC Pregnancy Childbirth, 18 (1), 41
DOI 10.1186/s12884-018-1666-8, PubMed 29361916

Kostovski E, Frigato E, Savikj M, Dahm A, Sandset PM, Mowinckel MC, Skretting G, Østerud B, Bertolucci C, Iversen PO (2018)
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation
Spinal Cord, 56 (11), 1076-1083
DOI 10.1038/s41393-018-0176-x, PubMed 29985456

Olsson M, Stanne TM, Pedersen A, Lorentzen E, Kara E, Martinez-Palacian A, Rønnow Sand NP, Jacobsen AF, Sandset PM, Sidelmann JJ, Engström G, Melander O, Kanse SM, Jern C (2018)
Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity
J Thromb Haemost, 16 (10), 2024-2034
DOI 10.1111/jth.14258, PubMed 30070759

Rodger M, Langlois N, Middeldorp S, Kahn S, Sandset PM, Brighton T, Huisman MV, Meyer G, Konstantinides S, Ageno W, Morange P, Garcia D, Kreuziger LB, Young L, Key N, Monreal M, Jiménez D (2018)
Initial strides for invent-VTE: Towards global collaboration to accelerate clinical research in venous thromboembolism
Thromb Res, 163, 128-131
DOI 10.1016/j.thromres.2018.01.050, PubMed 29407624

Sacco S, Merki-Feld GS, Ægidius KL, Bitzer J, Canonico M, Gantenbein AR, Kurth T, Lampl C, Lidegaard Ø, Anne MacGregor E, MaassenVanDenBrink A, Mitsikostas DD, Nappi RE, Ntaios G, Paemeleire K, Sandset PM, Terwindt GM, Vetvik KG, Martelletti P, European Headache Federation (EHF), the European Society of Contraception and Reproductive Health (ESCRH) (2018)
Effect of exogenous estrogens and progestogens on the course of migraine during reproductive age: a consensus statement by the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESCRH)
J Headache Pain, 19 (1), 76
DOI 10.1186/s10194-018-0896-5, PubMed 30171365

Sacco S, Merki-Feld GS, Ægidius KL, Bitzer J, Canonico M, Kurth T, Lampl C, Lidegaard Ø, Anne MacGregor E, MaassenVanDenBrink A, Mitsikostas DD, Nappi RE, Ntaios G, Sandset PM, Martelletti P, European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC) (2018)
Correction to: Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC)
J Headache Pain, 19 (1), 81
DOI 10.1186/s10194-018-0912-9, PubMed 30203397

Schultz NH, Holme PA, Bjørnsen S, Henriksson CE, Sandset PM, Jacobsen EM (2018)
The impact of rivaroxaban on primary hemostasis in patients with venous thrombosis
Platelets, 31 (1), 43-47
DOI 10.1080/09537104.2018.1557618, PubMed 30569801

Shapiro AD, Nakar C, Parker JM, Albert GR, Moran JE, Thibaudeau K, Thukral N, Hardesty BM, Laurin P, Sandset PM (2018)
Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency
Blood, 131 (12), 1301-1310
DOI 10.1182/blood-2017-09-806729, PubMed 29321155

Tavoly M, Wik HS, Sirnes PA, Jelsness-Jørgensen LP, Ghanima JP, Klok FA, Sandset PM, Ghanima W (2018)
The impact of post-pulmonary embolism syndrome and its possible determinants
Thromb Res, 171, 84-91
DOI 10.1016/j.thromres.2018.09.048, PubMed 30267974

Utne KK, Dahm A, Wik HS, Jelsness-Jørgensen LP, Sandset PM, Ghanima W (2018)
Rivaroxaban versus warfarin for the prevention of post-thrombotic syndrome
Thromb Res, 163, 6-11
DOI 10.1016/j.thromres.2018.01.013, PubMed 29324334

Publications 2017

Andresen MS, Ali HO, Myklebust CF, Sandset PM, Stavik B, Iversen N, Skretting G (2017)
Estrogen induced expression of tissue factor pathway inhibitor-2 in MCF7 cells involves lysine-specific demethylase 1
Mol Cell Endocrinol, 443, 80-88
DOI 10.1016/j.mce.2017.01.016, PubMed 28088469

Chollet ME, Andersen E, Skarpen E, Myklebust CF, Koehler C, Morth JP, Chuansumrit A, Pinotti M, Bernardi F, Thiede B, Sandset PM, Skretting G (2017)
Factor VII deficiency: Unveiling the cellular and molecular mechanisms underlying three model alterations of the enzyme catalytic domain
Biochim Biophys Acta Mol Basis Dis, 1864 (3), 660-667
DOI 10.1016/j.bbadis.2017.12.016, PubMed 29246447

Cui XY, Skretting G, Tinholt M, Stavik B, Dahm AEA, Sahlberg KK, Kanse S, Iversen N, Sandset PM (2017)
A novel hypoxia response element regulates oxygen-related repression of tissue factor pathway inhibitor in the breast cancer cell line MCF-7
Thromb Res, 157, 111-116
DOI 10.1016/j.thromres.2017.07.013, PubMed 28734156

Espada S, Stavik B, Holm S, Sagen EL, Bjerkeli V, Skjelland M, Dahl TB, Espevik T, Kanse S, Sandset PM, Skretting G, Halvorsen B (2017)
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages
Biochem Biophys Res Commun, 491 (2), 442-448
DOI 10.1016/j.bbrc.2017.07.070, PubMed 28712870

Garabet L, Ghanima W, Monceyron Jonassen C, Skov V, Holst R, Mowinckel MC, C Hasselbalch H, A Kruse T, Thomassen M, Liebman H, Bussel JB, Sandset PM (2017)
Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia
Platelets, 30 (2), 206-212
DOI 10.1080/09537104.2017.1394451, PubMed 29215956

Gravensteen IK, Jacobsen EM, Sandset PM, Helgadottir LB, Rådestad I, Sandvik L, Ekeberg Ø (2017)
Healthcare utilisation, induced labour and caesarean section in the pregnancy after stillbirth: a prospective study
BJOG, 125 (2), 202-210
DOI 10.1111/1471-0528.14750, PubMed 28516500

Krishnan K, Jusufovic M, Sandset PM, Sandset EC (2017)
Antiplatelet Therapy in Noncardioembolic Stroke: A Review of Current Evidence
Semin Neurol, 37 (3), 366-375
DOI 10.1055/s-0037-1603469, PubMed 28759917

Prebensen C, Trøseid M, Ueland T, Dahm A, Sandset PM, Aaberge I, Waalen K, Dyrhol-Riise AM, Taskén K, Kvale D (2017)
Immune activation and HIV-specific T cell responses are modulated by a cyclooxygenase-2 inhibitor in untreated HIV-infected individuals: An exploratory clinical trial
PLoS One, 12 (5), e0176527
DOI 10.1371/journal.pone.0176527, PubMed 28464042

Sacco S, Merki-Feld GS, Ægidius KL, Bitzer J, Canonico M, Kurth T, Lampl C, Lidegaard Ø, Anne MacGregor E, MaassenVanDenBrink A, Mitsikostas DD, Nappi RE, Ntaios G, Sandset PM, Martelletti P, European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC) (2017)
Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC)
J Headache Pain, 18 (1), 108
DOI 10.1186/s10194-017-0815-1, PubMed 29086160

Sagedal S, Sandvik L, Klingenberg O, Sandset PM (2017)
β-Thromboglobulin may not reflect platelet activation during haemodialysis with the HeprAN membrane
Scand J Clin Lab Invest, 77 (8), 679-684
DOI 10.1080/00365513.2017.1397288, PubMed 29117741

Schultz NH, Tran HTT, Bjørnsen S, Henriksson CE, Sandset PM, Holme PA (2017)
The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII against anticoagulation of Xa inhibitor
Thromb J, 15, 6
DOI 10.1186/s12959-017-0129-1, PubMed 28239301

Schultz NH, Tran HTT, Bjørnsen S, Henriksson CE, Sandset PM, Holme PA (2017)
The reversal effect of prothrombin complex concentrate (PCC), activated PCC and recombinant activated factor VII in apixaban-treated patients in vitro
Res Pract Thromb Haemost, 1 (1), 49-56
DOI 10.1002/rth2.12015, PubMed 30046673

Stavik B, Holm S, Espada S, Iversen N, Sporsheim B, Bjerkeli V, Dahl TB, Sandset PM, Skjelland M, Espevik T, Skretting G, Halvorsen B (2017)
Increased expression of TFPI in human carotid stenosis
Thromb Res, 155, 31-37
DOI 10.1016/j.thromres.2017.04.024, PubMed 28482260

Tikkinen KAO, Craigie S, Agarwal A, Siemieniuk RAC, Cartwright R, Violette PD, Novara G, Naspro R, Agbassi C, Ali B, Imam M, Ismaila N, Kam D, Gould MK, Sandset PM, Guyatt GH (2017)
Procedure-specific Risks of Thrombosis and Bleeding in Urological Non-cancer Surgery: Systematic Review and Meta-analysis
Eur Urol, 73 (2), 236-241
DOI 10.1016/j.eururo.2017.02.025, PubMed 28284738

Tikkinen KAO, Craigie S, Agarwal A, Violette PD, Novara G, Cartwright R, Naspro R, Siemieniuk RAC, Ali B, Eryuzlu L, Geraci J, Winkup J, Yoo D, Gould MK, Sandset PM, Guyatt GH (2017)
Procedure-specific Risks of Thrombosis and Bleeding in Urological Cancer Surgery: Systematic Review and Meta-analysis
Eur Urol, 73 (2), 242-251
DOI 10.1016/j.eururo.2017.03.008, PubMed 28342641

Wik HS, Enden TR, Ghanima W, Engeseth M, Kahn SR, Sandset PM (2017)
Diagnostic scales for the post-thrombotic syndrome
Thromb Res, 164, 110-115
DOI 10.1016/j.thromres.2017.10.022, PubMed 29126608

Wik HS, Ghanima W, Sandset PM, Kahn SR (2017)
Scoring Systems for Postthrombotic Syndrome
Semin Thromb Hemost, 43 (5), 500-504
DOI 10.1055/s-0037-1599142, PubMed 28470653

Publications 2016

Ali HO, Arroyo AB, González-Conejero R, Stavik B, Iversen N, Sandset PM, Martínez C, Skretting G (2016)
The role of microRNA-27a/b and microRNA-494 in estrogen-mediated downregulation of tissue factor pathway inhibitor α
J Thromb Haemost, 14 (6), 1226-37
DOI 10.1111/jth.13321, PubMed 26999003

Ali HO, Stavik B, Myklebust CF, Andersen E, Dahm AE, Iversen N, Sandset PM, Skretting G (2016)
Oestrogens Downregulate Tissue Factor Pathway Inhibitor through Oestrogen Response Elements in the 5'-Flanking Region
PLoS One, 11 (3), e0152114
DOI 10.1371/journal.pone.0152114, PubMed 26999742

Arntzen E, Sandset PM (2016)
[Specialist training for physicians - clear responsibility, better quality]
Tidsskr Nor Laegeforen, 136 (10), 898-9
DOI 10.4045/tidsskr.16.0402, PubMed 27272365

Arntzen E, Sandset PM (2016)
[Not Available]
Tidsskr Nor Laegeforen, 136 (12-13), 1062
DOI 10.4045/tidsskr.16.0520, PubMed 27381773

Bates SM, Alonso-Coello P, Tikkinen KA, Ebrahim S, Lopes LC, McDonald SD, Zhou Q, Akl EA, Neumann I, Jacobsen AF, Zhang Y, Santamaría A, Annichino-Bizzacchi JM, Sandset PM, Bitar W, Eckman MH, Guyatt GH (2016)
Women's values and preferences and health state valuations for thromboprophylaxis during pregnancy: A cross-sectional interview
Thromb Res, 140, 22-9
DOI 10.1016/j.thromres.2015.12.015, PubMed 27500301

Cui XY, Tinholt M, Stavik B, Dahm AE, Kanse S, Jin Y, Seidl S, Sahlberg KK, Iversen N, Skretting G, Sandset PM (2016)
Effect of hypoxia on tissue factor pathway inhibitor expression in breast cancer
J Thromb Haemost, 14 (2), 387-96
DOI 10.1111/jth.13206, PubMed 26598923

Garabet L, Gilboe IM, Mowinckel MC, Jacobsen AF, Mollnes TE, Sandset PM, Jacobsen EM (2016)
Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus
Scand J Immunol, 84 (2), 95-9
DOI 10.1111/sji.12445, PubMed 27135178

Haig Y, Enden T, Grøtta O, Kløw NE, Slagsvold CE, Ghanima W, Sandvik L, Hafsahl G, Holme PA, Holmen LO, Njaaastad AM, Sandbæk G, Sandset PM, CaVenT Study Group (2016)
Post-thrombotic syndrome after catheter-directed thrombolysis for deep vein thrombosis (CaVenT): 5-year follow-up results of an open-label, randomised controlled trial
Lancet Haematol, 3 (2), e64-71
DOI 10.1016/S2352-3026(15)00248-3, PubMed 26853645

Martin K, Beyer-Westendorf J, Davidson BL, Huisman MV, Sandset PM, Moll S (2016)
Use of the direct oral anticoagulants in obese patients: guidance from the SSC of the ISTH
J Thromb Haemost, 14 (6), 1308-13
DOI 10.1111/jth.13323, PubMed 27299806

Stavik B, Espada S, Cui XY, Iversen N, Holm S, Mowinkel MC, Halvorsen B, Skretting G, Sandset PM (2016)
EPAS1/HIF-2 alpha-mediated downregulation of tissue factor pathway inhibitor leads to a pro-thrombotic potential in endothelial cells
Biochim Biophys Acta, 1862 (4), 670-678
DOI 10.1016/j.bbadis.2016.01.017, PubMed 26826018

Tavoly M, Utne KK, Jelsness-Jørgensen LP, Wik HS, Klok FA, Sandset PM, Ghanima W (2016)
Health-related quality of life after pulmonary embolism: a cross-sectional study
BMJ Open, 6 (11), e013086
DOI 10.1136/bmjopen-2016-013086, PubMed 27810979

Tinholt M, Sandset PM, Iversen N (2016)
Polymorphisms of the coagulation system and risk of cancer
Thromb Res, 140 Suppl 1, S49-54
DOI 10.1016/S0049-3848(16)30098-6, PubMed 27067978

Tinholt M, Sandset PM, Mowinckel MC, Garred Ø, Sahlberg KK, Kristensen VN, Børresen-Dale AL, Jacobsen AF, Skretting G, Iversen N (2016)
Determinants of acquired activated protein C resistance and D-dimer in breast cancer
Thromb Res, 145, 78-83
DOI 10.1016/j.thromres.2016.08.003, PubMed 27505249

Tiscia GL, Dørum E, Myklebust CF, Grandone E, Sandset PM, Skretting G (2016)
Functional characterization of annexin A5 gene promoter allelic variants
Thromb Res, 144, 93-9
DOI 10.1016/j.thromres.2016.06.009, PubMed 27318245

Utne KK, Tavoly M, Wik HS, Jelsness-Jørgensen LP, Holst R, Sandset PM, Ghanima W (2016)
Health-related quality of life after deep vein thrombosis
Springerplus, 5 (1), 1278
DOI 10.1186/s40064-016-2949-z, PubMed 27547653

Publications 2015

Beitland S, Sandven I, Kjærvik LK, Sandset PM, Sunde K, Eken T (2015)
Thromboprophylaxis with low molecular weight heparin versus unfractionated heparin in intensive care patients: a systematic review with meta-analysis and trial sequential analysis
Intensive Care Med, 41 (7), 1209-19
DOI 10.1007/s00134-015-3840-z, PubMed 25971389

Berntsen CF, Kristiansen A, Akl EA, Sandset PM, Jacobsen EM, Guyatt G, Vandvik PO (2015)
Compression Stockings for Preventing the Postthrombotic Syndrome in Patients with Deep Vein Thrombosis
Am J Med, 129 (4), 447.e1-447.e20
DOI 10.1016/j.amjmed.2015.11.031, PubMed 26747198

Chollet ME, Skarpen E, Iversen N, Sandset PM, Skretting G (2015)
The chemical chaperone sodium 4-phenylbutyrate improves the secretion of the protein CA267T mutant in CHO-K1 cells trough the GRASP55 pathway
Cell Biosci, 5, 57
DOI 10.1186/s13578-015-0048-4, PubMed 26457178

Comerota AJ, Sandset PM, Konstantinides S, de Graaf R, Wakefield TW, Arnoldussen CW, Lam YL, van Gent WB, de Wolf MA, Catarinella FS, Kurstjens RL, Alshabatat A, Wittens CH (2015)
Theme 4: Invasive management of (recurrent) VTE and PTS
Thromb Res, 136 Suppl 1, S19-25
DOI 10.1016/j.thromres.2015.07.037, PubMed 26387732

Craigie S, Tsui JF, Agarwal A, Sandset PM, Guyatt GH, Tikkinen KA (2015)
Adherence to mechanical thromboprophylaxis after surgery: A systematic review and meta-analysis
Thromb Res, 136 (4), 723-6
DOI 10.1016/j.thromres.2015.06.023, PubMed 26140737

Dahm AE, Tiscia G, Holmgren A, Jacobsen AF, Skretting G, Grandone E, Sandset PM (2015)
Genetic variations in the annexin A5 gene and the risk of pregnancy-related venous thrombosis
J Thromb Haemost, 13 (3), 409-13
DOI 10.1111/jth.12817, PubMed 25495894

Eckman MH, Alonso-Coello P, Guyatt GH, Ebrahim S, Tikkinen KA, Lopes LC, Neumann I, McDonald SD, Zhang Y, Zhou Q, Akl EA, Jacobsen AF, Santamaría A, Annichino-Bizzacchi JM, Bitar W, Sandset PM, Bates SM (2015)
Women's values and preferences for thromboprophylaxis during pregnancy: a comparison of direct-choice and decision analysis using patient specific utilities
Thromb Res, 136 (2), 341-7
DOI 10.1016/j.thromres.2015.05.020, PubMed 26033397

Iversen PO, Dahm A, Skretting G, Mowinckel MC, Stranda A, Østerud B, Sandset PM, Kostovski E (2015)
Reduced peak, but no diurnal variation, in thrombin generation upon melatonin supplementation in tetraplegia. A randomised, placebo-controlled study
Thromb Haemost, 114 (5), 964-8
DOI 10.1160/TH15-05-0396, PubMed 26202881

Johnson KC, Aragaki AK, Jackson R, Reiner A, Sandset PM, Rosing J, Dahm AE, Rosendaal F, Manson JE, Martin LW, Liu S, Kuller LH, Cushman M, Rossouw JE (2015)
Tissue Factor Pathway Inhibitor, Activated Protein C Resistance, and Risk of Coronary Heart Disease Due To Combined Estrogen Plus Progestin Therapy
Arterioscler Thromb Vasc Biol, 36 (2), 418-24
DOI 10.1161/ATVBAHA.115.306905, PubMed 26681757

Kostovski E, Dahm AE, Mowinckel MC, Stranda A, Skretting G, Østerud B, Sandset PM, Iversen PO (2015)
Circadian rhythms of hemostatic factors in tetraplegia: a double-blind, randomized, placebo-controlled cross-over study of melatonin
Spinal Cord, 53 (4), 285-90
DOI 10.1038/sc.2014.243, PubMed 25644388

Sandset EC, Jusufovic M, Sandset PM, Bath PM, Berge E, SCAST Study Group (2015)
Effects of blood pressure-lowering treatment in different subtypes of acute ischemic stroke
Stroke, 46 (3), 877-9
DOI 10.1161/STROKEAHA.114.008512, PubMed 25657183

Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
J Acquir Immune Defic Syndr, 70 (4), 329-37
DOI 10.1097/QAI.0000000000000784, PubMed 26258571

Tinholt M, Stavik B, Louch W, Carlson CR, Sletten M, Ruf W, Skretting G, Sandset PM, Iversen N (2015)
Syndecan-3 and TFPI colocalize on the surface of endothelial-, smooth muscle-, and cancer cells
PLoS One, 10 (1), e0117404
DOI 10.1371/journal.pone.0117404, PubMed 25617766

Tinholt M, Vollan HK, Sahlberg KK, Jernström S, Kaveh F, Lingjærde OC, Kåresen R, Sauer T, Kristensen V, Børresen-Dale AL, Sandset PM, Iversen N (2015)
Tumor expression, plasma levels and genetic polymorphisms of the coagulation inhibitor TFPI are associated with clinicopathological parameters and survival in breast cancer, in contrast to the coagulation initiator TF
Breast Cancer Res, 17, 44
DOI 10.1186/s13058-015-0548-5, PubMed 25882602

Utne KK, Ghanima W, Foyn S, Kahn S, Sandset PM, Wik HS (2015)
Development and validation of a tool for patient reporting of symptoms and signs of the post-thrombotic syndrome
Thromb Haemost, 115 (2), 361-367
DOI 10.1160/th15-04-0318, PubMed 26422814

Wik HS, Jacobsen AF, Mowinckel MC, Sandset PM (2015)
The role of inflammation in post-thrombotic syndrome after pregnancy-related deep vein thrombosis: A population-based, cross-sectional study
Thromb Res, 138, 16-21
DOI 10.1016/j.thromres.2015.12.014, PubMed 26826503

Publications 2014

Ali HO, Stavik B, Dørum E, Iversen N, Sandset PM, Skretting G (2014)
Oestrogen induced downregulation of TFPI expression is mediated by ERα
Thromb Res, 134 (1), 138-43
DOI 10.1016/j.thromres.2014.04.004, PubMed 24785473

Haig Y, Enden T, Slagsvold CE, Sandvik L, Sandset PM, Kløw NE (2014)
Residual rates of reflux and obstruction and their correlation to post-thrombotic syndrome in a randomized study on catheter-directed thrombolysis for deep vein thrombosis
J Vasc Surg Venous Lymphat Disord, 2 (2), 123-30
DOI 10.1016/j.jvsv.2013.10.054, PubMed 26993176

Jacobsen AF, Kristiansen A, Bjørge L, Henriksen T, Eilertsen AL, Sandset PM (2014)
[Anticoagulation for venous thrombosis in pregnancy]
Tidsskr Nor Laegeforen, 134 (9), 926
DOI 10.4045/tidsskr.13.1605, PubMed 24828717

Jacobsen EM, Dahm AE, Vartdal T, Sandset PM (2014)
[Anticoagulation for venous thrombosis and internal diseases]
Tidsskr Nor Laegeforen, 134 (9), 924
DOI 10.4045/tidsskr.13.1597, PubMed 24828715

Kristiansen A, Brandt L, Agoritsas T, Akl EA, Berge E, Bondi J, Dahm AE, Granan LP, Halvorsen S, Holme PA, Flem Jacobsen A, Jacobsen EM, Neumann I, Sandset PM, Sætre T, Tveit A, Vartdal T, Guyatt G, Vandvik PO (2014)
Adaptation of trustworthy guidelines developed using the GRADE methodology: a novel five-step process
Chest, 146 (3), 727-734
DOI 10.1378/chest.13-2828, PubMed 25180723

Kristiansen A, Brandt L, Berge E, Dahm AE, Halvorsen S, Sandset PM, Vandvik PO (2014)
[New guidelines for antithrombotic therapy and thromboprophylaxis]
Tidsskr Nor Laegeforen, 134 (9), 921-2
DOI 10.4045/tidsskr.13.1582, PubMed 24828713

Pitkänen H, Jouppila A, Mowinckel MC, Lemponen M, Patiwael S, Sandset PM, Lassila R, Brinkman HJ (2014)
Enhanced thrombin generation and reduced intact protein S in processed solvent detergent plasma
Thromb Res, 135 (1), 167-74
DOI 10.1016/j.thromres.2014.10.020, PubMed 25466844

Sandset PM (2014)
Combined oral contraceptives increase risk of venous thrombosis according to oestrogen dose and type of progestogen
Evid Based Med, 19 (5), 194
DOI 10.1136/ebmed-2014-110011, PubMed 24948124

Subramaniam S, Thielmann I, Morowski M, Pragst I, Sandset PM, Nieswandt B, Etscheid M, Kanse SM (2014)
Defective thrombus formation in mice lacking endogenous factor VII activating protease (FSAP)
Thromb Haemost, 113 (4), 870-80
DOI 10.1160/TH14-06-0519, PubMed 25427855

Tavoly M, Jelsness-Jørgensen LP, Wik HS, Roaldsnes C, Sandset PM, Ghanima W (2014)
Quality of life after pulmonary embolism: first cross-cultural evaluation of the pulmonary embolism quality-of-life (PEmb-QoL) questionnaire in a Norwegian cohort
Qual Life Res, 24 (2), 417-25
DOI 10.1007/s11136-014-0779-4, PubMed 25120017

Tikkinen KA, Agarwal A, Craigie S, Cartwright R, Gould MK, Haukka J, Naspro R, Novara G, Sandset PM, Siemieniuk RA, Violette PD, Guyatt GH (2014)
Systematic reviews of observational studies of risk of thrombosis and bleeding in urological surgery (ROTBUS): introduction and methodology
Syst Rev, 3, 150
DOI 10.1186/2046-4053-3-150, PubMed 25540016

Tinholt M, Viken MK, Dahm AE, Vollan HK, Sahlberg KK, Garred O, Børresen-Dale AL, Jacobsen AF, Kristensen V, Bukholm I, Kåresen R, Schlichting E, Skretting G, Lie BA, Sandset PM, Iversen N (2014)
Increased coagulation activity and genetic polymorphisms in the F5, F10 and EPCR genes are associated with breast cancer: a case-control study
BMC Cancer, 14, 845
DOI 10.1186/1471-2407-14-845, PubMed 25407022

Publications 2013

Aamodt AH, Sandset PM, Atar D, Tveit A, Russell D (2013)
[Atrial fibrillation and stroke]
Tidsskr Nor Laegeforen, 133 (14), 1453-7
DOI 10.4045/tidsskr.12.0850, PubMed 23929293

Cui XY, Skretting G, Jing Y, Sun H, Sandset PM, Sun L (2013)
Hypoxia influences stem cell-like properties in multidrug resistant K562 leukemic cells
Blood Cells Mol Dis, 51 (3), 177-84
DOI 10.1016/j.bcmd.2013.05.003, PubMed 23725749

Enden T, Kløw NE, Sandset PM (2013)
Symptom burden and job absenteeism after treatment with additional catheter-directed thrombolysis for deep vein thrombosis
Patient Relat Outcome Meas, 4, 55-9
DOI 10.2147/PROM.S47233, PubMed 24082798

Enden T, Resch S, White C, Wik HS, Kløw NE, Sandset PM (2013)
Cost-effectiveness of additional catheter-directed thrombolysis for deep vein thrombosis
J Thromb Haemost, 11 (6), 1032-42
DOI 10.1111/jth.12184, PubMed 23452204

Enden T, Wik HS, Kvam AK, Haig Y, Kløw NE, Sandset PM (2013)
Health-related quality of life after catheter-directed thrombolysis for deep vein thrombosis: secondary outcomes of the randomised, non-blinded, parallel-group CaVenT study
BMJ Open, 3 (8), e002984
DOI 10.1136/bmjopen-2013-002984, PubMed 23988361

Ghanima W, Atar D, Sandset PM (2013)
New oral anticoagulants--a review
Tidsskr Nor Laegeforen, 133 (18), 1940-5
DOI 10.4045/tidsskr.12.1111, PubMed 24084970

Gravensteen IK, Helgadóttir LB, Jacobsen EM, Rådestad I, Sandset PM, Ekeberg O (2013)
Women's experiences in relation to stillbirth and risk factors for long-term post-traumatic stress symptoms: a retrospective study
BMJ Open, 3 (10), e003323
DOI 10.1136/bmjopen-2013-003323, PubMed 24154514

Helgadóttir LB, Turowski G, Skjeldestad FE, Jacobsen AF, Sandset PM, Roald B, Jacobsen EM (2013)
Classification of stillbirths and risk factors by cause of death--a case-control study
Acta Obstet Gynecol Scand, 92 (3), 325-33
DOI 10.1111/aogs.12044, PubMed 23157574

Iversen PO, Negaard H, Østenstad B, Sandset PM, Kolset SO (2013)
Evidence for long-term hypercoagulopathy, but normalization of markers of extracellular matrix turnover, in patients with non-Hodgkin lymphoma
Leuk Lymphoma, 56 (8), 2479-81
DOI 10.3109/10428194.2013.803227, PubMed 23656198

Raps M, Helmerhorst FM, Fleischer K, Dahm AE, Rosendaal FR, Rosing J, Reitsma P, Sandset PM, van Vliet HA (2013)
The effect of different hormonal contraceptives on plasma levels of free protein S and free TFPI
Thromb Haemost, 109 (4), 606-13
DOI 10.1160/TH12-10-0771, PubMed 23407778

Sandset PM (2013)
Genotype of proband and thrombophilia screening
Blood, 122 (15), 2528-9
DOI 10.1182/blood-2013-08-519801, PubMed 24113791

Sandset PM (2013)
Mechanisms of hormonal therapy related thrombosis
Thromb Res, 131 Suppl 1, S4-7
DOI 10.1016/S0049-3848(13)70009-4, PubMed 23452740

Stavik B, Tinholt M, Sletten M, Skretting G, Sandset PM, Iversen N (2013)
TFPIα and TFPIβ are expressed at the surface of breast cancer cells and inhibit TF-FVIIa activity
J Hematol Oncol, 6, 5
DOI 10.1186/1756-8722-6-5, PubMed 23320987

Whiteley WN, Adams HP, Bath PM, Berge E, Sandset PM, Dennis M, Murray GD, Wong KS, Sandercock PA (2013)
Targeted use of heparin, heparinoids, or low-molecular-weight heparin to improve outcome after acute ischaemic stroke: an individual patient data meta-analysis of randomised controlled trials
Lancet Neurol, 12 (6), 539-45
DOI 10.1016/S1474-4422(13)70079-6, PubMed 23642343

Wik HS, Jacobsen AF, Fagerland MW, Sandvik L, Sandset PM (2013)
Long-term mortality and incidence of cancer after pregnancy-related venous thrombosis: results of a population-based cohort study
Thromb Res, 131 (6), 497-501
DOI 10.1016/j.thromres.2013.04.035, PubMed 23726964

Publications 2012

Bergrem A, Dahm AE, Jacobsen AF, Sandvik L, Sandset PM (2012)
Differential haemostatic risk factors for pregnancy-related deep-vein thrombosis and pulmonary embolism: a population-based case-control study
Thromb Haemost, 108 (6), 1165-71
DOI 10.1160/TH12-05-0350, PubMed 23015030

Dahm AE, Bezemer ID, Bergrem A, Jacobsen AF, Jacobsen EM, Skretting G, Rosendaal FR, Sandset PM (2012)
Candidate gene polymorphisms and the risk for pregnancy-related venous thrombosis
Br J Haematol, 157 (6), 753-61
DOI 10.1111/j.1365-2141.2012.09121.x, PubMed 22533697

Dahm AE, Eilertsen AL, Goeman J, Olstad OK, Ovstebø R, Kierulf P, Mowinckel MC, Skretting G, Sandset PM (2012)
A microarray study on the effect of four hormone therapy regimens on gene transcription in whole blood from healthy postmenopausal women
Thromb Res, 130 (1), 45-51
DOI 10.1016/j.thromres.2011.12.009, PubMed 22217510

Enden T, Klow NE, Sandset PM (2012)
Catheter-directed thrombolysis for acute deep vein thrombosis Reply
Lancet, 379 (9828), 1786-1787

Enden T, Sandset PM, Kløw NE (2012)
Evidence-based practice for patients with severe venous thrombosis
Tidsskr Nor Laegeforen, 132 (10), 1215-6
DOI 10.4045/tidsskr.12.0474, PubMed 22669381

Ghanima W, Lee SY, Barsam S, Miller A, Sandset PM, Bussel JB (2012)
Venous thromboembolism and coagulation activity in patients with immune thrombocytopenia treated with thrombopoietin receptor agonists
Br J Haematol, 158 (6), 811-4
DOI 10.1111/j.1365-2141.2012.09227.x, PubMed 22816787

Gravensteen IK, Helgadottir LB, Jacobsen EM, Sandset PM, Ekeberg Ø (2012)
Long-term impact of intrauterine fetal death on quality of life and depression: a case-control study
BMC Pregnancy Childbirth, 12, 43
DOI 10.1186/1471-2393-12-43, PubMed 22676992

Haig Y, Enden T, Slagsvold CE, Sandvik L, Sandset PM, Kløw NE (2012)
Determinants of early and long-term efficacy of catheter-directed thrombolysis in proximal deep vein thrombosis
J Vasc Interv Radiol, 24 (1), 17-24; quiz 26
DOI 10.1016/j.jvir.2012.09.023, PubMed 23176966

Jacobsen AF, Sandset PM (2012)
Venous thromboembolism associated with pregnancy and hormonal therapy
Best Pract Res Clin Haematol, 25 (3), 319-32
DOI 10.1016/j.beha.2012.07.006, PubMed 22959548

Narverud I, Iversen PO, Aukrust P, Halvorsen B, Ueland T, Johansen SG, Nenseter MS, Sandset PM, Ulven SM, Ose L, Retterstøl K, Holven KB (2012)
Maternal familial hypercholesterolaemia (FH) confers altered haemostatic profile in offspring with and without FH
Thromb Res, 131 (2), 178-82
DOI 10.1016/j.thromres.2012.11.008, PubMed 23199546

Rossouw JE, Johnson KC, Pettinger M, Cushman M, Sandset PM, Kuller L, Rosendaal F, Rosing J, Wasserthal-Smoller S, Martin LW, Manson JE, Lakshminarayan K, Merino JG, Lynch J (2012)
Tissue factor pathway inhibitor, activated protein C resistance, and risk of ischemic stroke due to postmenopausal hormone therapy
Stroke, 43 (4), 952-7
DOI 10.1161/STROKEAHA.111.643072, PubMed 22363056

Sandset PM (2012)
CXCL4-platelet factor 4, heparin-induced thrombocytopenia and cancer
Thromb Res, 129 Suppl 1, S97-100
DOI 10.1016/S0049-3848(12)70026-9, PubMed 22682144

Skretting G, Iversen N, Myklebust CF, Dahm AE, Sandset PM (2012)
Overexpression of tissue factor pathway inhibitor in CHO-K1 cells results in increased activation of NF-κB and apoptosis mediated by a caspase-3 independent pathway
Mol Biol Rep, 39 (12), 10089-96
DOI 10.1007/s11033-012-1882-7, PubMed 22932941

Stavik B, Skretting G, Olstad OK, Sletten M, Dehli Vigeland M, Sandset PM, Iversen N (2012)
TFPI alpha and beta regulate mRNAs and microRNAs involved in cancer biology and in the immune system in breast cancer cells
PLoS One, 7 (10), e47184
DOI 10.1371/journal.pone.0047184, PubMed 23071754

Vandvik PO, Sandset PM (2012)
[Confusion regarding evidence-based advice]
Tidsskr Nor Laegeforen, 132 (10), 1204
DOI 10.4045/tidsskr.12.0490, PubMed 22669369

Wik HS, Jacobsen AF, Sandvik L, Sandset PM (2012)
Long-term impact of pregnancy-related venous thrombosis on quality-of-life, general health and functioning: results of a cross-sectional, case-control study
BMJ Open, 2 (6)
DOI 10.1136/bmjopen-2012-002048, PubMed 23144263

Wik HS, Jacobsen AF, Sandvik L, Sandset PM (2012)
Prevalence and predictors for post-thrombotic syndrome 3 to 16 years after pregnancy-related venous thrombosis: a population-based, cross-sectional, case-control study
J Thromb Haemost, 10 (5), 840-7
DOI 10.1111/j.1538-7836.2012.04690.x, PubMed 22452811

Publications 2011

Alatri A, Armstrong AE, Greinacher A, Koster A, Kozek-Langenecker SA, Lancé MD, Link A, Nielsen JD, Sandset PM, Spanjersberg AJ, Spannagl M (2011)
Results of a consensus meeting on the use of argatroban in patients with heparin-induced thrombocytopenia requiring antithrombotic therapy - a European Perspective
Thromb Res, 129 (4), 426-33
DOI 10.1016/j.thromres.2011.11.041, PubMed 22178575

Bergrem A, Dahm AE, Jacobsen AF, Mowinckel MC, Sandvik L, Sandset PM (2011)
Resistance to activated protein C is a risk factor for pregnancy-related venous thrombosis in the absence of the F5 rs6025 (factor V Leiden) polymorphism
Br J Haematol, 154 (2), 241-7
DOI 10.1111/j.1365-2141.2011.08712.x, PubMed 21564075

Enden T, Haig Y, Kløw NE, Slagsvold CE, Sandvik L, Ghanima W, Hafsahl G, Holme PA, Holmen LO, Njaastad AM, Sandbæk G, Sandset PM, CaVenT Study Group (2011)
Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial
Lancet, 379 (9810), 31-8
DOI 10.1016/S0140-6736(11)61753-4, PubMed 22172244

Ghanima W, Kleven IW, Enden T, Rosales A, Wik HS, Pederstad L, Holme PA, Sandset PM (2011)
Recurrent venous thrombosis, post-thrombotic syndrome and quality of life after catheter-directed thrombolysis in severe proximal deep vein thrombosis
J Thromb Haemost, 9 (6), 1261-3
DOI 10.1111/j.1538-7836.2011.04298.x, PubMed 21489133

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
Incidence and risk factors of fetal death in Norway: a case-control study
Acta Obstet Gynecol Scand, 90 (4), 390-7
DOI 10.1111/j.1600-0412.2011.01079.x, PubMed 21306337

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
The association of inherited thrombophilia and intrauterine fetal death: a case-control study
Blood Coagul Fibrinolysis, 22 (8), 651-6
DOI 10.1097/MBC.0b013e32834a614c, PubMed 22198364

Helgadottir LB, Skjeldestad FE, Jacobsen AF, Sandset PM, Jacobsen EM (2011)
The association of antiphospholipid antibodies with intrauterine fetal death: a case-control study
Thromb Res, 130 (1), 32-7
DOI 10.1016/j.thromres.2011.11.029, PubMed 22178574

Kostovski E, Dahm AE, Iversen N, Hjeltnes N, Østerud B, Sandset PM, Iversen PO (2011)
Melatonin stimulates release of tissue factor pathway inhibitor from the vascular endothelium
Blood Coagul Fibrinolysis, 22 (4), 254-9
DOI 10.1097/MBC.0b013e3283442ce2, PubMed 21297449

Lassila R, Antovic JP, Armstrong E, Baghaei F, Dalsgaard-Nielsen J, Hillarp A, Holme PA, Holmström M, Johnsson H, Joutsi-Korhonen L, Sandset PM (2011)
Practical viewpoints on the diagnosis and management of heparin-induced thrombocytopenia
Semin Thromb Hemost, 37 (3), 328-36
DOI 10.1055/s-0031-1274516, PubMed 21455867

Negaard HF, Sandset PM, Kolset SO, Svennevig K, Østenstad B, Iversen PO (2011)
Associations between regulators of extracellular matrix and hemostatic factors in hematologic neoplasias
Leuk Lymphoma, 52 (6), 1157-9
DOI 10.3109/10428194.2011.563886, PubMed 21463121

Pettersen FO, Torheim EA, Dahm AE, Aaberge IS, Lind A, Holm M, Aandahl EM, Sandset PM, Taskén K, Kvale D (2011)
An exploratory trial of cyclooxygenase type 2 inhibitor in HIV-1 infection: downregulated immune activation and improved T cell-dependent vaccine responses
J Virol, 85 (13), 6557-66
DOI 10.1128/JVI.00073-11, PubMed 21490090

Stavik B, Skretting G, Aasheim HC, Tinholt M, Zernichow L, Sletten M, Sandset PM, Iversen N (2011)
Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility
BMC Cancer, 11, 357
DOI 10.1186/1471-2407-11-357, PubMed 21849050

Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2011)
Protein C mutation (A267T) results in ER retention and unfolded protein response activation
PLoS One, 6 (8), e24009
DOI 10.1371/journal.pone.0024009, PubMed 21901152

Wik HS, Enden TR, Jacobsen AF, Sandset PM (2011)
Long-term quality of life after pregnancy-related deep vein thrombosis and the influence of socioeconomic factors and comorbidity
J Thromb Haemost, 9 (10), 1931-6
DOI 10.1111/j.1538-7836.2011.04468.x, PubMed 21848904

Publications 2010

Bergrem A, Jacobsen EM, Skjeldestad FE, Jacobsen AF, Skogstad M, Sandset PM (2010)
The association of antiphospholipid antibodies with pregnancy-related first time venous thrombosis--a population-based case-control study
Thromb Res, 125 (5), e222-7
DOI 10.1016/j.thromres.2009.12.006, PubMed 20051285

Dahm AE, Bezemer ID, Sandset PM, Rosendaal FR (2010)
Interaction between tissue factor pathway inhibitor and factor V levels on the risk of venous thrombosis
J Thromb Haemost, 8 (5), 1130-2
DOI 10.1111/j.1538-7836.2010.03805.x, PubMed 20149077

Enden T, Storås TH, Negård A, Haig Y, Sandvik L, Gjesdal KI, Sandset PM, Kløw NE (2010)
Visualization of deep veins and detection of deep vein thrombosis (DVT) with balanced turbo field echo (b-TFE) and contrast-enhanced T1 fast field echo (CE-FFE) using a blood pool agent (BPA)
J Magn Reson Imaging, 31 (2), 416-24
DOI 10.1002/jmri.22046, PubMed 20099355

Jacobsen AF, Dahm A, Bergrem A, Jacobsen EM, Sandset PM (2010)
Risk of venous thrombosis in pregnancy among carriers of the factor V Leiden and the prothrombin gene G20210A polymorphisms
J Thromb Haemost, 8 (11), 2443-9
DOI 10.1111/j.1538-7836.2010.04038.x, PubMed 20735725

Krarup LH, Sandset EC, Sandset PM, Berge E (2010)
D-dimer levels and stroke progression in patients with acute ischemic stroke and atrial fibrillation
Acta Neurol Scand, 124 (1), 40-4
DOI 10.1111/j.1600-0404.2010.01409.x, PubMed 20726843

Kringen MK, Narum S, Lygren I, Seljeflot I, Sandset PM, Trøseid AM, Johansen PW, Brørs O, Holthe MR (2010)
Reduced platelet function and role of drugs in acute gastrointestinal bleeding
Basic Clin Pharmacol Toxicol, 108 (3), 194-201
DOI 10.1111/j.1742-7843.2010.00643.x, PubMed 21118353

Opstad TB, Eilertsen AL, Høibraaten E, Skretting G, Sandset PM (2010)
Tissue factor pathway inhibitor polymorphisms in women with and without a history of venous thrombosis and the effects of postmenopausal hormone therapy
Blood Coagul Fibrinolysis, 21 (6), 516-21
DOI 10.1097/MBC.0b013e32833a06cd, PubMed 20453636

Reikvam Å, Sandset PM (2010)
Warfarinbehandling i praksis: tryggere antikoagulasjon
Den norske legeforening, Oslo (2. utg.), 72 s.
BIBSYS 102255148, ISBN 978-82-8070-083-4

Sandset PM (2010)
Immunobiology of heparin-induced thrombocytopenia
Curr Top Microbiol Immunol, 341, 193-202
DOI 10.1007/82_2010_17, PubMed 20369319

Sandset PM, Arnesen H, Jacobsen AF, Wergeland H (2010)
Prophylaxis against prosthetic mitral valve thrombosis with unfractionated heparin administered by an elastometric infusion pump
Thromb Res, 126 (3), e232-4
DOI 10.1016/j.thromres.2010.05.005, PubMed 20553950

Sandset PM, Francis C (2010)
Thrombosis Research--affiliation with the European Thrombosis Research Organization (ETRO)
Thromb Res, 125 (1), 1
DOI 10.1016/j.thromres.2010.01.008, PubMed 20171348

Skretting G, Stavik B, Landvik NE, Myklebust CF, Iversen N, Zienolddiny S, Sandset PM (2010)
Functional characterization of polymorphisms in the human TFPI gene
Biochem Biophys Res Commun, 397 (1), 106-11
DOI 10.1016/j.bbrc.2010.05.078, PubMed 20519147

Stavik B, Skretting G, Sletten M, Sandset PM, Iversen N (2010)
Overexpression of both TFPIα and TFPIβ induces apoptosis and expression of genes involved in the death receptor pathway in breast cancer cells
Mol Carcinog, 49 (11), 951-63
DOI 10.1002/mc.20679, PubMed 20886581

Tjeldhorn L, Iversen N, Sandvig K, Bergan J, Sandset PM, Skretting G (2010)
Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport
BMC Cell Biol, 11, 67
DOI 10.1186/1471-2121-11-67, PubMed 20815936

Publications 2009

Abildgaard U, Sandset PM, Hammerstrøm J, Gjestvang FT, Tveit A (2009)
Management of pregnant women with mechanical heart valve prosthesis: thromboprophylaxis with low molecular weight heparin
Thromb Res, 124 (3), 262-7
DOI 10.1016/j.thromres.2008.12.005, PubMed 19162303

Enden T, Kløw NE, Sandvik L, Slagsvold CE, Ghanima W, Hafsahl G, Holme PA, Holmen LO, Njaastad AM, Sandbaek G, Sandset PM, CaVenT study group (2009)
Catheter-directed thrombolysis vs. anticoagulant therapy alone in deep vein thrombosis: results of an open randomized, controlled trial reporting on short-term patency
J Thromb Haemost, 7 (8), 1268-75
DOI 10.1111/j.1538-7836.2009.03464.x, PubMed 19422443

Negaard HF, Svennevig K, Kolset SO, Iversen N, Lothe IM, Østenstad B, Sandset PM, Iversen PO (2009)
Alterations in regulators of the extracellular matrix in non-Hodgkin lymphomas
Leuk Lymphoma, 50 (6), 998-1004
DOI 10.1080/10428190902889270, PubMed 19373600

Sandset PM, Francis C (2009)
Thrombosis Research: Introduction of e-pages
Thromb Res, 124 (3), 251
DOI 10.1016/j.thromres.2009.06.001, PubMed 19596224

Sandset PM, Francis C, Key N (2009)
Guidelines of the Italian Society for Haemostasis and Thrombosis (SISET)
Thromb Res, 124 (5), 515
DOI 10.1016/j.thromres.2009.09.021, PubMed 19837232

Sandset PM, Høibraaten E, Eilertsen AL, Dahm A (2009)
Mechanisms of thrombosis related to hormone therapy
Thromb Res, 123 Suppl 2, S70-3
DOI 10.1016/S0049-3848(09)70015-5, PubMed 19217481

Tjeldhorn L, Sandset PM, Haugbro K, Skretting G (2009)
Hereditary protein C deficiency caused by the Ala267Thr mutation in the protein C gene is associated with symptomatic and asymptomatic venous thrombosis
Thromb Res, 125 (3), 230-4
DOI 10.1016/j.thromres.2009.05.013, PubMed 19535131

Publications 2008

Eilertsen AL, Karssemeijer N, Skaane P, Qvigstad E, Sandset PM (2008)
Differential impact of conventional and low-dose oral hormone therapy, tibolone and raloxifene on mammographic breast density, assessed by an automated quantitative method
BJOG, 115 (6), 773-9
DOI 10.1111/j.1471-0528.2008.01690.x, PubMed 18355366

Eilertsen AL, Sandvik L, Steinsvik B, Sandset PM (2008)
Differential impact of conventional-dose and low-dose postmenopausal hormone therapy, tibolone and raloxifene on C-reactive protein and other inflammatory markers
J Thromb Haemost, 6 (6), 928-34
DOI 10.1111/j.1538-7836.2008.02970.x, PubMed 18394014

Enden T, Garratt AM, Kløw NE, Sandset PM (2008)
Assessing burden of illness following acute deep vein thrombosis: data quality, reliability and validity of the Norwegian version of VEINES-QOL/Sym, a disease-specific questionnaire
Scand J Caring Sci, 23 (2), 369-74
DOI 10.1111/j.1471-6712.2008.00618.x, PubMed 19068041

Hofstad B, Nesbakken A, Eritsland J, Brørs O, Sandset PM (2008)
[Should platelet inhibitors be discontinued before gastrointestinal endoscopy?]
Tidsskr Nor Laegeforen, 128 (21), 2440-2
PubMed 19096466

Jacobsen AF, Skjeldestad FE, Sandset PM (2008)
Ante- and postnatal risk factors of venous thrombosis: a hospital-based case-control study
J Thromb Haemost, 6 (6), 905-12
DOI 10.1111/j.1538-7836.2008.02961.x, PubMed 18363820

Negaard HF, Iversen N, Bowitz-Lothe IM, Sandset PM, Steinsvik B, Ostenstad B, Iversen PO (2008)
Increased bone marrow microvascular density in haematological malignancies is associated with differential regulation of angiogenic factors
Leukemia, 23 (1), 162-9
DOI 10.1038/leu.2008.255, PubMed 18800145

Negaard HF, Iversen PO, Østenstad B, Iversen N, Holme PA, Sandset PM (2008)
Hypercoagulability in patients with haematological neoplasia: no apparent initiation by tissue factor
Thromb Haemost, 99 (6), 1040-8
DOI 10.1160/TH07-09-0541, PubMed 18521506

Negaard HF, Iversen PO, Ostenstad B, Mowinckel MC, Sandset PM (2008)
Increased acquired activated protein C resistance in unselected patients with hematological malignancies
J Thromb Haemost, 6 (9), 1482-7
DOI 10.1111/j.1538-7836.2008.03060.x, PubMed 18573186

Skretting G, Lien T, Sandset PM, Iversen N (2008)
Expression of the V264M TFPI mutant in endothelial cell cultures may involve mRNA stability
Thromb Res, 123 (6), 851-5
DOI 10.1016/j.thromres.2008.09.003, PubMed 19007969

Publications 2007

Andresen MS, Eilertsen AL, Abildgaard U, Sandset PM (2007)
Hormone therapy and raloxifene reduce the coagulation inhibitor potential
Blood Coagul Fibrinolysis, 18 (5), 455-60
DOI 10.1097/MBC.0b013e32813a2de7, PubMed 17581320

Berge E, Haug KB, Sandset EC, Haugbro KK, Turkovic M, Sandset PM (2007)
The factor V Leiden, prothrombin gene 20210GA, methylenetetrahydrofolate reductase 677CT and platelet glycoprotein IIIa 1565TC mutations in patients with acute ischemic stroke and atrial fibrillation
Stroke, 38 (3), 1069-71
DOI 10.1161/01.STR.0000258076.04860.8e, PubMed 17290027

Dahm AE, Sandset PM, Rosendaal FR (2007)
The association between protein S levels and anticoagulant activity of tissue factor pathway inhibitor type 1
J Thromb Haemost, 6 (2), 393-5
DOI 10.1111/j.1538-7836.2007.02859.x, PubMed 18045239

Eilertsen AL, Liestøl S, Mowinckel MC, Hemker HC, Sandset PM (2007)
Differential impact of conventional and low-dose oral hormone therapy (HT), tibolone and raloxifene on functionality of the activated protein C system
Thromb Haemost, 97 (6), 938-43
DOI 10.1160/TH06-11-0632, PubMed 17549295

Enden T, Sandvik L, Kløw NE, Hafsahl G, Holme PA, Holmen LO, Ghanima W, Njaastad AM, Sandbaek G, Slagsvold CE, Sandset PM (2007)
Catheter-directed Venous Thrombolysis in acute iliofemoral vein thrombosis--the CaVenT study: rationale and design of a multicenter, randomized, controlled, clinical trial (NCT00251771)
Am Heart J, 154 (5), 808-14
DOI 10.1016/j.ahj.2007.07.010, PubMed 17967583

Ghanima W, Abdelnoor M, Holmen LO, Nielssen BE, Sandset PM (2007)
The association between the proximal extension of the clot and the severity of pulmonary embolism (PE): a proposal for a new radiological score for PE
J Intern Med, 261 (1), 74-81
DOI 10.1111/j.1365-2796.2006.01733.x, PubMed 17222170

Ghanima W, Nielssen BE, Holmen LO, Witwit A, Al-Ashtari A, Sandset PM (2007)
Multidetector computed tomography (MDCT) in the diagnosis of pulmonary embolism: interobserver agreement among radiologists with varied levels of experience
Acta Radiol, 48 (2), 165-70
DOI 10.1080/02841850601100859, PubMed 17354136

Ghanima W, Sandset PM (2007)
Risk stratification of pulmonary embolism by computed tomography
J Intern Med, 262 (6), 702
DOI 10.1111/j.1365-2796.2007.1858.x, PubMed 17944881

Jacobsen AF, Skjeldestad FE, Sandset PM (2007)
Incidence and risk patterns of venous thromboembolism in pregnancy and puerperium--a register-based case-control study
Am J Obstet Gynecol, 198 (2), 233.e1-7
DOI 10.1016/j.ajog.2007.08.041, PubMed 17997389

Jensen T, Kierulf P, Sandset PM, Klingenberg O, Joø GB, Godal HC, Skjønsberg OH (2007)
Fibrinogen and fibrin induce synthesis of proinflammatory cytokines from isolated peripheral blood mononuclear cells
Thromb Haemost, 97 (5), 822-9
DOI 10.1160/th07-01-0039, PubMed 17479194

Liestøl S, Sandset PM, Mowinckel MC, Wisløff F (2007)
Activated protein C resistance determined with a thrombin generation-based test is associated with thrombotic events in patients with lupus anticoagulants
J Thromb Haemost, 5 (11), 2204-10
DOI 10.1111/j.1538-7836.2007.02734.x, PubMed 17958739

Tchaikovski SN, van Vliet HA, Thomassen MC, Bertina RM, Rosendaal FR, Sandset PM, Helmerhorst FM, Tans G, Rosing J (2007)
Effect of oral contraceptives on thrombin generation measured via calibrated automated thrombography
Thromb Haemost, 98 (6), 1350-6
DOI 10.1160/TH07-07-0439, PubMed 18064335

van Vliet HA, Bertina RM, Dahm AE, Rosendaal FR, Rosing J, Sandset PM, Helmerhorst FM (2007)
Different effects of oral contraceptives containing different progestogens on protein S and tissue factor pathway inhibitor
J Thromb Haemost, 6 (2), 346-51
DOI 10.1111/j.1538-7836.2007.02863.x, PubMed 18067603

Publications 2006

Amundsen AL, Khoury J, Sandset PM, Seljeflot I, Ose L, Tonstad S, Henriksen T, Retterstøl K, Iversen PO (2006)
Altered hemostatic balance and endothelial activation in pregnant women with familial hypercholesterolemia
Thromb Res, 120 (1), 21-7
DOI 10.1016/j.thromres.2006.07.001, PubMed 16914186

Dahm A, Osterud B, Hjeltnes N, Sandset PM, Iversen PO (2006)
Opposite circadian rhythms in melatonin and tissue factor pathway inhibitor type 1: does daylight affect coagulation?
J Thromb Haemost, 4 (8), 1840-2
DOI 10.1111/j.1538-7836.2006.02048.x, PubMed 16879232

Dahm A, Rosendaal FR, Andersen TO, Sandset PM (2006)
Tissue factor pathway inhibitor anticoagulant activity: risk for venous thrombosis and effect of hormonal state
Br J Haematol, 132 (3), 333-8
DOI 10.1111/j.1365-2141.2005.05876.x, PubMed 16409298

Dahm AE, Iversen N, Birkenes B, Ree AH, Sandset PM (2006)
Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1
BMC Cardiovasc Disord, 6, 40
DOI 10.1186/1471-2261-6-40, PubMed 17029634

Eilertsen AL, Qvigstad E, Andersen TO, Sandvik L, Sandset PM (2006)
Conventional-dose hormone therapy (HT) and tibolone, but not low-dose HT and raloxifene, increase markers of activated coagulation
Maturitas, 55 (3), 278-87
DOI 10.1016/j.maturitas.2006.04.012, PubMed 16713143

Eilertsen AL, Sandvik L, Mowinckel MC, Andersen TO, Qvigstad E, Sandset PM (2006)
Differential effects of conventional and low dose oral hormone therapy (HT), tibolone, and raloxifene on coagulation and fibrinolysis
Thromb Res, 120 (3), 371-9
DOI 10.1016/j.thromres.2006.10.013, PubMed 17156824

Enden T, Kløw NE, Sandset PM (2006)
[Catheter-directed thrombolysis in acute deep venous thrombosis]
Tidsskr Nor Laegeforen, 126 (13), 1765
PubMed 16794675

Ghanima W, Abdelnoor M, Holmen LO, Nielssen BE, Ross S, Sandset PM (2006)
D-dimer level i