Farbod Bahreini

Farbod Bahreini

Luebeck, Germany

E-mail: [email protected]

researchgate.net/profile/Farbod_Bahreini

Personal Statement

PhD candidate in Immunology with a strong background in biochemistry, molecular biology, and cancer-related research. Experienced in protein analysis, T cell receptor diversity, and enzyme kinetics. Proficient in establishing scientific connections and fostering collaborative research. As a certified peer-reviewer for Elsevier, I bring a critical eye to scientific literature and aim to apply my expertise to drive innovation in academic and industry research settings.

Fields of Interest

Cancer Biology, Immunology, Autoimmunity, Nanoparticles, Biochemistry, Molecular Genetics

Education

University of Luebeck

Ph.D., Immunology, January 2022 until now

Thesis: CD4+ T cell receptor sequences during progression towards experimental pemphigoid Supervisor: Prof. Dr. Kathrin Kalies

Tarbiat Modares University

M.Sc, Biochemistry, September 2018 until September 2021

Thesis: Investigation of structural, activity, and stability alterations of lactate dehydrogenase in the presence of different additives

Supervisor: Prof. Dr. Khosro Khajeh

Guilan University

B.Sc, Cell and Molecular Biology, September 2014 until April 2018

Thesis: The relation between miR-559 gene polymorphism and the incidence of breast and gastric cancers

Supervisors: Prof. Dr. Zivar Salehi, Dr. Shirin Shahangian

Research & Professional Experience

Research Assistant, Department of Anatomy

University of Luebeck, Luebeck, Germany (2022 - Present)

Mentored Bachelor’s and Master's students and researched autoimmune skin blistering diseases.

Research Assistant, Department of Biochemistry

Tarbiat Modares University, Tehran, Iran (2019 - 2021)

Sample preparation and data analysis for the project on hyaluronic acid extraction from rooster comb

Research Assistant, Department of Biochemistry

Tarbiat Modares University, Tehran, Iran (2018 - 2019)

Cloning and expression of GDNF protein, sample preparation, and data analysis

Affiliations 

 2014-2020 Department of Biology, Faculty of Sciences, University of Guilan, Rasht, Iran

2018- 2021  Department of Biochemistry, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran 

2022-present Institute of Anatomy, University of Luebeck, Luebeck, Germany

2020- present Network of Immunity in Infection, Malignancy, and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

Technical Skills

•  Laboratory Techniques: Next-generation sequencing, Laser microdissection, Cloning, Gene expression, Protein stability, Enzyme kinetics, ELISA, Western Blot, Chromatography, PCR, Real-time PCR, Flow Cytometry, DNA/RNA extraction, Animal Handling (Certified FELASA handler), ZetaView, Nanosight, Cell Culture

•  Data Analysis Tools: GraphPad Prism, FlowJo, MedCalc, Microsoft Office, Excel, PowerPoint, Adobe Photoshop

•  Programming:

R (Intermediate): Analyzed NGS results of T cell receptor repertoire diversity using packages like ggplot2, vegan, dplyr, and immunarch for statistical analysis and visualization.

C (Intermediate): Developed problem-solving and algorithmic skills through coursework applicable to bioinformatics tasks like data processing and simulations.

Python (Familiar): Learned data science basics, including data manipulation (pandas), visualization (matplotlib), and introductory machine learning.

Notable Educational Projects

• 
  

   Academic Papers

  
  

1. 1- Bahreini F, Ramezani S, Shahangian SS, Salehi Z, Mashayekhi F. miR-559 polymorphism rs58450758 is linked to breast cancer. British journal of biomedical science. 2020 Jan 2;77(1):29-34.


2. 2- Bahreini F, Rayzan E, Rezaei N. microRNA‐related single‐nucleotide polymorphisms and breast cancer. Journal of Cellular Physiology. 2021 Mar;236(3):1593-605.


3. 3- Torabi S, Bahreini F, Rezaei N. The role of angiotensin-converting enzyme 2 in COVID-19 induced lung injury. Acta Bio Medica: Atenei Parmensis. 2020;91(4).


4. 4- Torabi S, Bahreini F, Rezaei N. Gallium Components-Based Drug Delivery: A Potential Treatment for COVID-19. Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders). 2022 May 1;22(3):1-3.


5. 5- Bahreini F, Rayzan E, Rezaei N. MicroRNAs and Diabetes Mellitus Type 1. Current Diabetes Reviews. 2021 Feb 14.


6. 6- Taleb M, Mohammadkhani N, Bahreini F, Ovais M, Nie G. Modulation of Tumor Vasculature Network: Key Strategies. Small Structures. 2022 Mar 29:2100164.


7. 7- Ebrahimi K, Shir Ovand S, Mohammedi AA, Nabi-Afjadi M, Zalpoor H, Bahreini F. Biosynthesis of Copper Nanoparticles Using Aqueous Thymus daenensis (Celak) Flora and Investigation of Its Antifungal Activity. Journal of Medical Microbiology and Infectious Diseases. 2022 Sep 10;10(3):98-103.


8. 8- Bahreini F, Niebuhr M, Belde J, Westermann J, Kalies K. Protocol to Isolate Germinal Centers by Laser Microdissection. Bio-protocol. 2022 Jun 5;12(11):e4431-.


9. 9- Bahreini F, Niebuhr M, Belde J, Bieber K, Westermann J, Kalies K. Protocol to Induce Follicular T Helper Cells, Germinal Centers, and Skin Lesions in Mouse Models for Skin Blistering Diseases. Bio-protocol. 2022 May 20;12(10):e4414-.


10. 10- Bahreini F, Jabbari P, Gossing W, Aziziyan F, Frohme M, Rezaei N. The role of noncoding RNAs in pituitary adenoma. Epigenomics. 2021 Sep;13(17):1421-37.


11. 11- Niebuhr M, Bahreini F, Fähnrich A, Bomholt C, Bieber K, Schmidt E, Ibrahim S, Hammers CM, Kalies K. Analysis of T cell repertoires of CD45RO CD4 T cells in cohorts of patients with bullous pemphigoid: A pilot study. Frontiers in Immunology. 2022;13.


12. 12- Mirtavoos‐Mahyari H, Ajami S, Mehrtash A, Marashiyan SM, Bahreini F, Sheikhy K, Ghanbari S, Ardeshirdavani A. Clinical whole‐exome sequencing analysis reveals a novel missense COL11A1 mutation resulting in an 18‐week Iranian male aborted fetus with Fibrochondrogenesis 1: A case report. Clinical Case Reports. 2022 Nov;10(11):e6574.


13. 13- Azari M, Bahreini F, Uversky VN, Rezaei N. Current Therapeutic Approaches and Promising Perspectives of Using Bioengineered Peptides in Fighting Chemoresistance in Triple-Negative Breast Cancer. Biochemical Pharmacology. 2023 Feb 20:115459.


14. 14- Koolivand Z, Bahreini F, Rayzan E, Rezaei N. Inducing Apoptosis in Acute Myeloid Leukemia; Mechanisms and Limitations. Heliyon 2024

•  Book Chapter

1. Bahreini F, Rezaei N. The role of microRNAs in chemoresistance. Handbook of Cancer and Immunology. DOI: 10.1007/978-3-030-80962-1_336-1 

Academic Service

•  Reviewer for Heliyon, Cancer Genetics, Archives of Community Medicine and Public Health, SCIOLBiomedicine, Archives of Pathology and Clinical Research

Congress participation

·         International congress on autoimmune pre-disease-2024

Poster title: T Cell Receptor Repertoire Analysis During the Pathogenesis of the Autoimmune Skin Blistering Disease Epidermolysis Bullosa Acquisita

·         Conference: 50th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF)-2024

Poster title: T Cell Receptor Repertoire Analysis During the Pathogenesis of the Autoimmune Skin Blistering Disease Epidermolysis Bullosa Acquisita

·         Conference: 49th Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung (ADF)- 2023

Poster title: Cell-derived nanoparticles regulate the pro-inflammatory cytokine secretion in the murine macrophage cell line J774A.1

·         4th International & 16th Iranian Genetics Congress-2020

Poster title: Investigation of recombinant Lactate Dehydrogenase Expression using SUMO fusion tag

·         Conference: 16th National Congress of Biochemistry & 7th International Congress of Biochemistry & Molecular Biology 2020

 Poster title: Investigating the effect of natural deep eutectic solvents on lactate dehydrogenase activity and stability

·         Conference: Third International and Fifteenth Iranian Genetics Congress-2018

Poster title: Correlation between miR-559 gene polymorphism and susceptibility to gastric cancer

·         Conference: 3rd international and 11th national biotechnology congress of Islamic Republic of Iran-2019

Poster title: In-silico analyses to investigate miR-559 gene polymorphism and incidence of breast cancer

Certificates

FELASA (Animal handling)

Peer-reviewing for journals under ELSEVIER

Grant

DAAD-RISE Program Funding (2024). Co-authored DAAD-RISE application, securing funding for a 3-month internship.

Languages

Persian (Native), English (Fluent), Arabic (Familiar), German (Basic)