Alessandro Poggi
USERN Advisory Board
Dr Alessandro Poggi has been working on cellular and tumor immunology for more than 25 years. He is authors of 203 original articles published on indexed journals and he is a reviewer of several scientific journals. Starting from his first doctoral degree in Biological Sciences (1982), he worked on functional characteristics of leukocyte subsets. After his Post-Doctoral Fellow training at the Ludwig Cancer Institute in Lausanne, Switzerland (1985-1987), he has been appointed as Assistant Member at the IST (Immunopathology Unit) in Genoa studying natural killer cell development and function, molecular aspects of survival of subsets of leukocytes and the role of mesenchymal stromal and stem cells in tumor microenvironment. In 2000, he has taken his second doctoral degree in Medicine and Surgery and from July 2009, he is director of the Molecular Oncology and Angiogenesis Unit at the IRCCS AOU San Martino IST in Genoa.
Education
University of Genoa
November 2000 - November 2004
Allergy and Clinical Immunology Specialist
Allergy and Immunology
University of Genoa
October 1993 - October 2000
MD
Medicine
University of Genoa
November 1983 - November 1987
Specialist in General Pathology
Pathology
University of Genoa
October 1978 - December 1982
Genova, Italy
PhD
Biology
Professional experience
Azienda Ospedaliera Universitaria San Martino di Genova
January 2011 - Present
Head of Unit of Molecular Oncology and Angiogenesis
Azienda Ospedaliera Universitaria San Martino di Genova
January 2009 - December 2011
Department of Medical Oncology Integrated
Head of Molecular Oncology and Angiogeensis Unit
National Institute for Cancer Research Genoa
January 1996 - June 2009
Assistant Member
Università degli Studi di Genova
January 1991 - December 2012
Dipartimento di Medicina sperimentale (DIMES)
Azienda Ospedaliera Universitaria San Martino di Genova
January 1989 - December 2012
National Institute for Cancer Research Genoa
Ludwig Institute for Cancer Research
June 1985 - December 1987
PHD fellow
Mechanisms of T cell activation and signal transduction.
Scientific Societies
1987-1999: Gruppo di Cooperazione in Immunologia. 1999-2001: Società Italiana di Immunologia (ex Gruppo di Cooperazione in Immunologia) 1989-2003: Gruppo Italiano di Citometria 1990-today: European Association for Cancer Research 1990-today: Società Italiana di Ematologia Sperimentale 1991-1999: Società Italiana di Biochimica 2001-today: Società Italiana di Immunologia Clinica e Allergologia 2002-2004: American Association of Immunologists 2004-today: European Association of Hematology
Most cited publications
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes
Authors: Moretta, A; Biassoni, R; Bottino, C; ... Moretta, L
Published: Feb 1997 in Immunological Reviews
DOI: 10.1111/J.1600-065X.1997.TB00943.X
The human leukocyte antigen (HLA)-C-specific ''activatory'' or ''inhibitory'' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions
Authors: Biassoni, R; Cantoni, C; Falco, M; ... Moretta, L
Published: Feb 1996 in Journal of Experimental Medicine
DOI: 10.1084/JEM.183.2.645
Phospholipases C and A(2) control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes
Authors: Andrei, C; Margiocco, P; Poggi, A; ... Rubartelli, A
Published: Jun 2004 in Proceedings of the National Academy of Sciences
DOI: 10.1073/PNAS.0308558101
Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NKCD8(+) cells and inhibit cytotoxic T cell activity through CD8 ligation
Authors: Contini, P; Ghio, M; Poggi, A; ... Puppo, F
Published: 2003 in European Journal of Immunology
DOI: 10.1002/IMMU.200390015
NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1
Authors: Semino, C; Angelini, G; Poggi, A; Rubartelli, A
Published: Jul 2005 in Blood
DOI: 10.1182/BLOOD-2004-10-3906
Education
University of Genoa
November 2000 - November 2004
Allergy and Clinical Immunology Specialist
Allergy and Immunology
University of Genoa
October 1993 - October 2000
MD
Medicine
University of Genoa
November 1983 - November 1987
Specialist in General Pathology
Pathology
University of Genoa
October 1978 - December 1982
Genova, Italy
PhD
Biology
Professional experience
Azienda Ospedaliera Universitaria San Martino di Genova
January 2011 - Present
Head of Unit of Molecular Oncology and Angiogenesis
Azienda Ospedaliera Universitaria San Martino di Genova
January 2009 - December 2011
Department of Medical Oncology Integrated
Head of Molecular Oncology and Angiogeensis Unit
National Institute for Cancer Research Genoa
January 1996 - June 2009
Assistant Member
Università degli Studi di Genova
January 1991 - December 2012
Dipartimento di Medicina sperimentale (DIMES)
Azienda Ospedaliera Universitaria San Martino di Genova
January 1989 - December 2012
National Institute for Cancer Research Genoa
Ludwig Institute for Cancer Research
June 1985 - December 1987
PHD fellow
Mechanisms of T cell activation and signal transduction.
Scientific Societies
1987-1999: Gruppo di Cooperazione in Immunologia. 1999-2001: Società Italiana di Immunologia (ex Gruppo di Cooperazione in Immunologia) 1989-2003: Gruppo Italiano di Citometria 1990-today: European Association for Cancer Research 1990-today: Società Italiana di Ematologia Sperimentale 1991-1999: Società Italiana di Biochimica 2001-today: Società Italiana di Immunologia Clinica e Allergologia 2002-2004: American Association of Immunologists 2004-today: European Association of Hematology
Most cited publications
Major histocompatibility complex class I-specific receptors on human natural killer and T lymphocytes
Authors: Moretta, A; Biassoni, R; Bottino, C; ... Moretta, L
Published: Feb 1997 in Immunological Reviews
DOI: 10.1111/J.1600-065X.1997.TB00943.X
The human leukocyte antigen (HLA)-C-specific ''activatory'' or ''inhibitory'' natural killer cell receptors display highly homologous extracellular domains but differ in their transmembrane and intracytoplasmic portions
Authors: Biassoni, R; Cantoni, C; Falco, M; ... Moretta, L
Published: Feb 1996 in Journal of Experimental Medicine
DOI: 10.1084/JEM.183.2.645
Phospholipases C and A(2) control lysosome-mediated IL-1 beta secretion: Implications for inflammatory processes
Authors: Andrei, C; Margiocco, P; Poggi, A; ... Rubartelli, A
Published: Jun 2004 in Proceedings of the National Academy of Sciences
DOI: 10.1073/PNAS.0308558101
Soluble HLA-A,-B,-C and -G molecules induce apoptosis in T and NKCD8(+) cells and inhibit cytotoxic T cell activity through CD8 ligation
Authors: Contini, P; Ghio, M; Poggi, A; ... Puppo, F
Published: 2003 in European Journal of Immunology
DOI: 10.1002/IMMU.200390015
NK/iDC interaction results in IL-18 secretion by DCs at the synaptic cleft followed by NK cell activation and release of the DC maturation factor HMGB1
Authors: Semino, C; Angelini, G; Poggi, A; Rubartelli, A
Published: Jul 2005 in Blood
DOI: 10.1182/BLOOD-2004-10-3906
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