Paulo Bueno

Professor Paulo R. Bueno is the coordinator of the Nanobionics research group (www.nanobionics.pro.br) at São Paulo State University, UNESP. He published over 200 papers related to fundaments and applications of electric and electrochemistry time-dependent (including gravimetric and optical impedance) spectroscopic methods (h index 50, > 8700 citations with an average citation of higher than 28 per article, Google Scholar). His main scientific interest is focused on the fundaments and technological applications associated with electron charge transfer, transport and storage occurring at molecular and nanoscale structures. Under his guidance Nanobionics group develops synthetic structures and surfaces that mimic molecular and biological structures aiming applications in highly-relevant diagnostic devices. The Nanobionics group developed a totally new label-free diagnostic assay based on an electroanalytical spectroscopic methodology supported on the use of the electrochemistry capacitance, i.e. a capacitance proportional to the electrochemical density of states that intrinsically exists in mesoscopic structures comprised of redox-active molecules when attached over an electrode. These impedance-derived assays are able to detect target protein at femtomolar levels allowing the early detection of clinically relevant targets that are better than those currently commercial. They are potentially cheap and can be multiplexed. Other relevant aspects of his groups? activities are the synthesis of self-assembled redox-tagged peptides and its applications in redox capacitive biosensors. The advantages of constructing a peptide-based receptive surface containing electrochemical tags are that peptides can be easily manipulated and optimized for applications containing complex biological environments. This tailoring ability avoids fouling and concomitantly can substitute antibodies by peptide or DNA aptamers as receptors with equivalent or superior affinity as well as specificity.

Since 2008 Professor Bueno is engaged with tech transfer initiatives involving public-private startup tech transfer projects with Scientific and Technological Parks in Sao Paulo. Because of such initiatives, Professor Bueno was invited to a plenary conference in the USA ? Washington in 2009 by the US National Council of Entrepreneurial Tech Transfer in which Brazilian Tech Transfer context was introduced and discussed with the US and European Tech Transfer related agents and agencies. He is also engaged with UNESP internationalization program. Finally, he acted as academic and researcher visitor several times in European universities such as Universities of Valence and Jaume I (Spain), University of Paris (France) and University of Oxford. His collaborative work has been the subject of two significant awards from The Royal Society in the UK (a Brian Mercer Award in 2013 and a Newton Fellowship in 2015). His is currently administrating a Fellowship of Royal Society (Research Fellows Director, https://royalsociety.org/people/paulo-roberto-bueno-12682/). He is Fellows of Royal Society of Chemistry (FRSC) in the UK and member of American Chemical Society (ACS) in the USA. Also, he is a member of The Electrochemical Society (ECS) and International Society of Electrochemistry (ISE). Professor Bueno is the co-founder of Osler Diagnostics (http://oslerdiagnostics.com/), a start-up company from the University of Oxford. 

Academic graduation / title:



1999 - 2003

PhD in Physical Chemistry .

Federal University of São Carlos, UFSCAR, Brazil.

Title: Study of Interleaving Kinetics of Li + ions in Nb2O5 and WO3 Films. Emphasis on Electric and Optical Modulated Frequency Techniques., Obtained year: 2003.

Advisor: Luis Otavio de Sousa Bulhões.

Scholarship holder: São Paulo State Research Support Foundation, FAPESP, Brazil.

Keywords: Thin films; Relaxation processes; Impedance spectroscopy; Modulated transmittance; Transmission lines; Insulation electrodes.

Major Area: Exact and Earth

Sciences Large Area: Exact and Earth Sciences / Area: Chemistry / Subarea: Physico-Chemistry / Specialty: Electrochemistry.

Major Area: Exact and Earth Sciences / Area: Physics / Subarea: Condensed Matter Physics / Specialty: Prop. Optics and Spectroscopy. from Mat. Condens; Other Inter. da Mat. with Rad. e Part ..

Activity sectors: Development of New Materials; Electro-Electronic Industry; Energy.



1997 - 1999

Master in Materials Science and Engineering (CAPES Concept 7) .

Federal University of São Carlos, UFSCAR, Brazil.

Title: Obtaining Translucent Ceramics based on SnO2 and TiO2 for Application in Electro-optical and Photochemical Devices, Year of Achievement: 1999.

Advisor: Luis Otávio de Sousa Bulhões.

Scholarship holder: São Paulo State Research Support Foundation, FAPESP, Brazil.

Keywords: Thin films; Impedance spectroscopy; sol-gel; sintering; Spinodal decomposition; Photochemistry.

Major Area: Engineering

Major Area: Exact and Earth Sciences / Area: Physics / Subarea: Condensed Matter Physics / Specialty: Transp. Electronics and Prop. Surface Electric; Interfaces and Films.

Major Area: Exact and Earth Sciences / Area: Physics / Subarea: Condensed Matter Physics / Specialty: Equation of State, Balance of Phases and Phase Transitions.

Activity sectors: Development of New Materials.



1998 - 1999

Specialization in Production Management . (Hours: 336h).

Federal University of São Carlos, UFSCAR, Brazil.



1992 - 1996

Graduation in Materials Engineering.

Federal University of São Carlos, UFSCAR, Brazil.

Title: Preparation and Characterization of Oxides with Spinel-like Structure.

Advisor: Luis Otavio de Sousa Bulhões.

Scholarship holder: São Paulo State Research Support Foundation, FAPESP, Brazil.

Postdoctoral and Free Teaching:

2012

Free teaching.

Paulista State University Júlio de Mesquita Filho, UNESP, Brazil.

Title: Transfer Functions in the Study of Physicochemical Systems and Processes, Year obtained: 2012.

Keywords: Impedance spectroscopy; Optical Transfer Function; Mass Transfer Function; Capacitance spectroscopy.

Major Area: Exact and Earth Sciences



2003

Post doctoral.

University of São Paulo, USP, Brazil.

Scholarship holder: São Paulo State Research Support Foundation, FAPESP, Brazil.

Major Area: Exact and Earth

Sciences Large Area: Exact and Earth Sciences / Area: Chemistry / Subarea: Physico-Chemistry / Specialty: Química do Estado Condensado.

Major Area: Exact and Earth Sciences / Area: Chemistry / Subarea: Physico-Chemistry / Specialty: Electrochemistry.

Professional performance:



University of Oxford, OX, England.

2010 - 2010

Visiting Professor





Universidad Jaume I de Castellon, UJC, Spain.

2009 - 2009

Visiting Professor





Universitat de València, UV, Spain.

2008 - 2008

Visiting Professor





Paulista State University Júlio de Mesquita Filho, UNESP, Brazil.

2013 - Current

Government Employee, Adjunct Professor



2012 - Current

Adjunct Professor



2005 - 2012

Assistant Professor Doctor





Center National de la Recherche Scientifique, CNRS, France.

2004 - 2006

Visiting Professor





University of São Paulo, USP, Brazil.

2003 - 2004

Scholar-doctor





Universidad Jaume I, UJI, Spain.

2001 - 2001

Employee, Doctorate Internship

Mixcim Indústria e Comércio Ltda, MIXCIN, Brazil.

1996 - 1997

Employee, Trainee

Research lines:



1. Synthesis, Characterization and Study of the Processing of Polyanilines for Technological Application

2. Study of relaxation processes in electrochromic oxide films by optical impedance spectroscopy

3. Electrochemical Solid State and Surface

4. Electrochemical Impedance Spectroscopy

5. Solid State Chemistry

6. Oxide Semiconductors

7. Transfer Functions

8. Biosensors and Electrogravimetry

9. Bioelectrochemistry

10. Investigation of molecular solids (hexacyanoferrates) by means of ac and dc electrogravimetry

11. Thermodynamic and Kinetic Study of Insertion Reactions by Multi-Transfer Function Approach

12. Structural characterization of electrochemically synthesized hexacyanoferrates containing potassium ion by means of synchrotron X-ray powder diffraction

Languages:



English

Spanish

French







Awards and titles:



2021 Honorary Advisor Member, USERN.

2020 PCCP HOT Articles - The nanoscopic principles of capacitive ion sensing interfaces, Royal Society of Chemistry.

2020 Member of ACS Sensors Editorial Advisory Board, American Chemical Society.

2018 UK Government Recognition of Exceptional Talent Rights, Royal Society and UK Immigration Office.

2018 CAPES Award for best thesis in the area of ​​Chemistry, Coordination for the Improvement of Higher Education Personnel - CAPES.

2017 ACS outstanding referee, American Chemical Society.

2017 Royal Society Exceptional Talent Endorsement, Royal Society.

2016 Fellow of the Royal Society of Chemistry, Royal Society of Chemistry.

2016 Honorable Mention of the Capes Thesis Award 2016 in the area of ​​CHEMISTRY, CAPES.

2016 Fellow member of ECS, The Electrochemical Society.

2015 ACS award in the paper: Measuring Quantum Capacitance in Energetically Addressable Molecular Layers, ACS - American Chemical Society.

2015 ACS award in recognition of engagements with Society´s mission, ACS - American Chemical Society.

2015 Top Authors Elsevier - Label Free Redox Capacitive Biosensing, Elsevier.

2015 Top Authors Elsevier - An optimized electrochemical biosensor for the label-free detection of C-reactive protein in blood, Elsevier.

2015 Royal Society Award - Newton Advanced Fellowship, Royal Society.

2015 American Chemical Society Fellow Member, ACS.

2015 Royal Society Fellow, Royal Society.

2012 Brian Mercer Feasibility, Royal Society, London, United Kingdom.

2010 Professor Paraninfo of the Graduation Class of 2009 Graduation, UNESP, Institute of Chemistry.

2004 Who's Who in Science and Engineering, Marquis.

2004 Incorporating Living Science, International Biographical Center Cambridge.

2003 Who's Who in Science and Engineering, Marquis.

1998 An article published in the Journal of Materials Science was featured in this journal, Kluwer Academic Publishers.

Most cited publication:

A new SnO2-based varistor system

SA Pianaro, PR Bueno, E Longo, JA Varela

Journal of materials science letters 14 (10), 692-694 1995



Impedance of constant phase element (CPE)-blocked diffusion in film electrodes

J Bisquert, G Garcia-Belmonte, P Bueno, E Longo, LOS Bulhoes

Journal of Electroanalytical Chemistry 452 (2), 229-234 1998



SnO2, ZnO and related polycrystalline compound semiconductors: an overview and review on the voltage-dependent resistance (non-ohmic) feature

PR Bueno, JA Varela, E Longo

Journal of the European Ceramic Society 28 (3), 505-529 2008



Theoretical models for ac impedance of finite diffusion layers exhibiting low frequency dispersion

J Bisquert, G Garcia-Belmonte, F Fabregat-Santiago, PR Bueno

Journal of Electroanalytical Chemistry 475 (2), 152-163 1999



Investigation of the electrical properties of  varistor system using impedance spectroscopy

PR Bueno, SA Pianaro, EC Pereira, LOS Bulhoes, E Longo, JA Varela

Journal of Applied Physics 84 (7), 3700-3705 1998



Effect of Bi2O3 addition on the microstructure and electrical properties of the SnO2. CoO. Nb2O5 varistor system

SA Pianaro, PR Bueno, P Olivi, E Longo, JA Varela

Journal of Materials Science Letters 16 (8), 634-638 1997