Arianna Di Stadio

Date prepared:            June 18, 2020

Name: Arianna Di Stadio

Office Address: Department of Otolaryngology

University Hospital of Perugia

E-mail: [email protected]

Place of Birth: Roma, Italy

Languages: Italian, English, French

Research expertise:  NEURODEGENERATIVE DISEASE

National Academic Certification and Qualification: qualified as Associate Professor in Audiology and Neuro-otology

Education

9/2016- 7/2017 “Certification in Applied Biostatistic” Harvard Medical School Boston, MA, USA

11/2003-01/2007 “PhD - Advanced Audiology Technologies” La Sapienza University, Rome, Italy

1992-1999 “MD – Medicine”  La Sapienza University,  Rome, Italy

Post-doctoral training

03/2015-02/2017 “Senior Research Fellow Otology and Laryngology” Harvard Medical School, Boston, MA

09/2012-06/2014 “Clinical Fellow Facial Plastic and Reconstructive Surgery” Segalen University, Bordeaux, France

09/2009-06/2011 “Clinical Fellow Microsurgery” Paris 13 University, Paris, France    

05/2008-05/2009 “Clinical Fellow European Academy of Facial Plastic Surgery” See page 3                       

10/1999-11/2003 “Resident (summa cum laude) Otolaryngology” La Sapienza University, Rome, Italy

Additional Course

2017 “Medical writer in Science” (Two Months course with final exam: achieved) Stanford University, CA, USA                                  

2016 “DNA replication and Repair” (Three months course) MIT, Boston (MA), USA                                                   

2016 “Precision Medicine” (Two months on line course) George Town University, Washington DC, USA                                               

2016 “Useful in GENETIC” (Four months course with final exam: achieved) British Columbia University, Vancouver (CA)                                   

Faculty Academic Appointments

2019- “Honorary Research Associate”, Neuroinflammation Laboratory, UCL, London, UK

2018- “Coordinator Research activities of the Otolaryngology Department (Associate professor rank)” University of Perugia, Perugia, Italy

2017- 2018 “Temporary Assistant Professor (Research Assistant)” University of Padua, Padua, Italy                                            

2006-2007 “Coordinator of the Audiology & Speech Language” Therapy Program, Audiometric Techniques Graduate School La Sapienza University, Rome, Italy                                                         

2003-2007 “Adjunct professor, Image Elaboration and Laboratory I” School of Information Science, University of Bologna, Cesena campus, Italy

Appointments at Hospitals

05/ 2017- 07/2018 “Responsible Otolaryngology Research Line” IRCCS San Camillo, Venice, Italy

01/2013-06/2013 “Investigator, Head and Neck Oncology”           Maxillo-Facial Surgery Department, Pitié-Salpêtrière Hospital, Paris, France                                                                  

04/2012-07/2012 “Assistant Physician” Head and Neck Oncology Department, Centre Mèdical de Forcilles, Férolles-Attilly, France

12/2011-03/2012“Consultant, ENT and Microsurgery” HUDERFF Children University Hospital, Brussels, Belgium

06/2009-09/2011“Consultant, Facial Nerve Disorders” Head and Neck Neuroscience Department, San Camillo-Forlanini Hospital Rome, Italy                                          

09/2007-05/2008 “Consultant, Facial Nerve Disorders” Otology Center (Mario Sanna, MD, director), Rome, Italy                           

01/2007-05/2008 “Consultant, Facial Nerve Disorders” Head and Neck Neuroscience Department, San Camillo-Forlanini Hospital Rome, Italy          

08/2004-12/2006 “Assistant Physician” Facial Paralysis Center Otolaryngology Department,  Policlinico Umberto I University Hospital, Rome, Italy                                                                                                                                   

09/2004-12/2006“Consultant for Facial Nerve Disorders” Infective Disease Department, Policlinico Umberto I University Hospital, Rome, Italy   

Professional Societies

2017-   Full- Member European Academy of Otology & Neuro-Otology (EAONO)                                                                               

2016- Full-Member International Otopathology Schuknecht Society

2014-  Member Association for Sleep Disorders (ASSIREM)        

2008-   Full-Member European Academy   Facial   Plastic Surgery (EAFPS)

Invited Grant Review Activities

2014- Ad Hoc Reviewer Italian Association for Multiple Sclerosis, Rome, Italy                                       

2013-2016 Temporary Reviewer the Evaluation of National Research Protocols, ANSM Agence National de Santè Medicale, Paris, France                                                                                                

Invited Editorial Activities

Period of time   Janaury 2020   January 2019-current January 2019- current   June 2018-current   May 2018-current   March 2018-current   February 2018-current     February 2018-current     January 2018-current   January 2018-current   April 2017-current August 2017-current   September 2017-current   January 2017-current     November 2016-current   September 2016-current     June 2016-current      April 2016-current     January 2016- October 2016     2015-current     2015-current     2015-current     2014-current      2013-current

Role  Associate Editor and Chief Medical Research section   Ad Hoc Reviewer Ad Hoc Reviewer Ad Hoc Reviewer    Ad Hoc Reviewer    Associate Editor Ad Hoc Reviewer      Ad Hoc Reviewer       Associate Editor   Ad Hoc Reviewer    Ad Hoc Reviewer      Ad Hoc Reviewer      Associate Editor Editor in Chief     Ad Hoc Reviewer    Associate Editor   Associate Editor     Ad Hoc Reviewer  Guest Editor Ad Hoc Reviewer  Editor in Chief      Ad Hoc Reviewer  Ad Hoc Reviewer      Ad Hoc Reviewer

Journal   Life      Eu Arch Otorhinolaryngology Neuroradiology    JoVE PluONE Clinical Case Report Wiley     Clinical Research in Dermatology   Advanced Drug Delivery Review    Australasian Medical Journal   Audiology and Neurotology    Hearing balance and communication     BMC Ear, Nose and Throat Disorders      Insights of neuroncology    Heighpubs Otolaryngology and Rhinology     Journal of Proteome Research    Heighpubs Otolaryngology and Rhinology   Journal of Otolaryngology ENT Research                                 Ophthalmic plastic and reconstructive surgery journal   The journal of International medical research- Special  issue ORL  Science PJ     Otorhinolaryngology-Open Journal   International clinical oral and maxillofacial Surgery     International Journal of Speech Technology   Laryngoscope

HONORS and AWARDS:

2008 European Academy of Facial Plastic Surgery (EAFPS) Fellowship

Each year, EAFPS awards three, funded 1-year clinical fellowships to surgeons from all over Europe. Winners have the opportunity to train at the most prestigious European centers of Facial Plastics and Maxillofacial Surgery. A minimum of 200 surgical procedures is required to complete the fellowship. Fellows are expected to follow the rules of the International Federation of Facial Plastic Surgery Societies (IFFPSS) for the United International Certification in Facial Plastic Surgery (UIC). Recipients are eligible to sit the American Academy of Facial Plastic Surgery (AAFPRS) exam under the auspices of the IFFPS

Formal teaching of Peers (Organization of CME Courses)

2017 CHDEAF International Conference, 16-18 November, Naples (300 partecipants)

2017 CORLAP National Conference, 27 February, Padua University (300 participants)

2017 Clermond-Ferrand International workshop, 28 March, Clermont-Ferrand, France (100 participants)

2016 Imcas International Conference, 28-31 January, Paris France (5500 participants)

2015 “Cosmetology 2015” International Meeting, 22-24 June, Philadelphia USA (preview more than 450 participants).

2000 “OSAS 2000 International Course in Obstructive Sleep Disorders”, Rome Italy (300 participants).

Invited Presentation

01/29/2016 “The genetic approach to anti-aging”, IMCAS 2016, Paris France

06/23/2015 “New philosophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA.

06/24/2015 “My face Complex® my idea of anti-age supplement” and “New philosophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA.

1/28/2005“Rehabilitation of Facial Palsy “Facial Nerve Paralysis”, Team Facial Plastic Surgery Congress Roma Congress, Roma.

11/26/2004“Facial Nerve paralysis: clinical staging and etiology” “Facial Nerve Paralysis”, Team Facial Plastic Surgery Congress Roma.

March/1-4/2000 “Maxillo-facial abnormalities causes or outcomes of Osas?” ROMA OSAS 2000 Roma.

Report of Clinical Activities and Innovations

Current Licensure and Certification

British Medical Council (UK) 02/2019-

Board of Doctor and Surgeon Rome (Italy) 01/2001-

Board of Doctor and Surgeon Paris (France) 03/2009-2018

Board of Doctor and Surgeon Bruxelles (Belgium) 12/2011-12/2012

06/2009 EAFPS Fellow 

Practice Activities

10/2014- Specialist and Clinical Coordinator Centre Facial Disorders, ArSMedica Clinic, Rome, Italy (Treatment of Facial Palsy from Diagnosis to rehabilitation technique).

9/2013- ENT and Facial Plastic Surgeon, Villa Luisa Clinic, Rome Italy (General ENT treatment, medical and surgery antiage therapy).

01/2013- 06/2013 Investigator in cancer research at the Maxillo Facial Department at the Pitié-Salpêtrière Hospital in Paris, France.

04/2012 – 07/2012: Assistant Physician ENT oncology department at the Centre Mèdical de Forcilles, France.

12/2011 – 03/2012: Pediatric ENT and Micro Surgeon specialist at the Huderff Children university hospital in Brussels, Belgium.

01/2011-09/2011: Consultant and clinical researcher in facial paralysis disease at the otorhinolaryngology department San Camillo/Forlanini Hospital, Rome, Italy.

06/2009-09/2011: Attending surgeon Maxillofacial and Facial Plastic department, San Camillo hospital in Rome, Italy.

09/2007-05/2008 Otology Centre in Rome directed by Prof Mario Sanna as a consulting physician specialist in facial nerve disorders.

01/2007-05/2008 Attending Surgeon Department of Facial-maxillo and Plastic-reconstructive surgery San Camillo hospital in Rome, Italy.

08/2004 to 31/12/2006  Responsible  of  the  Unit  for  Treatment  of  Facial  Paralysis  in  the  ENT Department of  “La Sapienza” University of Rome, Italy.

09/2004 Advisor at the clinic of Infective Diseases of the Policlinico Umberto I for the treatment and rehabilitation of Facial Paralysis.

Clinical Innovations

My Face Complex: This supplement is useful as aging disease treatment. The components of this product are indicated in the treatment of: neuronal and vascular disease, articulation disease, immune deficit disease. The supplement restores the substance that lost during aging. 

Otoage: This supplement has been created for treatment of Tinnitus and related age hearing loss. This is an antioxidant cocktail able to preserve the vascular and neuronal function. 

Report of Technological and other Scientific Innovation

Research Look on line platform October 2015

DAAR Patent application IT 0001379177, 1 august 2007

In collaboration with Dr Damiana Lazzaro of Bologna University Created this software able to analyze the prosody signal in the voice.

Report of Scholarship

Peer Reviewed Publications

1. Severini C, Barbato C, Gabanella F, Di Stadio A, et al. Alzheimer’s disease: new concepts on the role of autoimmunity and of NLRP3 inflammasome in the pathogenesis of the disease. Current Neuropharmacology in press.
2. Di Stadio A, della Volpe A, Ralli M, Korsch F, Greco A, Ricci G. Spiral ganglions and speech perception in the elderly. Which turn of the cochlea is the more relevant? A preliminary study on human temporal bones. Int J Advan Oto in press
3. Smith J, Chen M, Balakrishnan K, Sidell D, Di Stadio A, Schechtman S, Brody R,Kupfer R, Rassekh C, Brenner M. Difficult Airway and Aerosol Generating Procedures in COVID-19: Timeless Principles for Uncertain Times. Otolaryngology Head and Neck Surgery in press
4. Arianna Di Stadio, Antonio della Volpe, Fiammetta M Korsch, Antonietta De Lucia, Massimo Ralli, Francesco Martines, Giampietro Ricci.Difensil Immuno reduces recurrence and severity of tonsillitis in children: a randomized controlled trial. Nutrients in press
5. Di Stadio A, et Al. AdHear ® improves memory function, and speech perception and recognition in patients with Single Side Hearing Loss: a pilot study. International Journal of Advanced Otology in press.
6. A. Di Stadio, A. Della Volpe, M. Ralli, G. Ricci Gender differences in COVID-19 infection. The estrogen effect on upper and lower airways. Can it help to figure out a treatment? Eur Rev Med Pharmacol Sci 2020; 24 (10): 5195-5196 . 
7. Arianna Di Stadio, Giampietro Ricci, Antonio Greco, Marco de Vincentiis and Massimo Ralli Mortality rate and gender differences in COVID-19 patients dying in Italy: A comparison with other countries. Eur Rev Med Pharmacol Sci 2020; 24 (8): 4066-4067
8. Ralli M, Di Stadio A, Greco A, de Vincentiis M, Polimeni A Defining the burden of olfactory dysfunction in COVID-19 patients. Eur Rev Med Pharmacol Sci 2020; 24 (7): 3440-3441
9. Arianna Di Stadio, Daniela Messineo, Massimo Ralli, Dalila Roccamatisi, Angela Musacchio, Giampietro Ricci, Antonio Greco. The impact of white matter hyperintensities on speech perception Neurological Science doi: 10.1007/s10072-020-04295-8
10. Roberta Marozzo, Valentina Pegoraro, Laura Dipietro, Massimo Ralli, Corrado Angelini & Arianna Di Stadio(2020): Can miR-34a be suitable for monitoring sensorineural hearing loss in patients with mitochondrial disease? A case series. International Journal of Neuroscience, doi: 10.1080/00207454.2020.1731505
11. Arianna Di Stadio, Massimo Ralli, Daniela Messineo, Giuseppe Ciancia, Annamaria Cascone, Giovanni Salzano, Marco De Vincentiis, Francesco Antonio Salzano. Septal nasal extramedullary plasmacytoma: a rare tumor located in an unusual area. Ear Nose Throat J. 2020 Mar 15:145561320911735. doi: 10.1177/0145561320911735
12. Messineo D, Ralli M, Greco A, Di Stadio A. Double Ring in Cochlear Otosclerosis: A Limit to Cochlear Implantation? The Solution Is the Surgical Approach. Ear Nose Throat J. 2019 Dec 16:145561319895601. doi: 10.1177/0145561319895601
13. Musacchio A, Corrao CRN, Altissimi G, Scarpa A, Girolamo SD, Di Stadio A, Greco A, Ralli M. Workplace noise exposure and audiometric thresholds in dental technicians. Int Tinnitus J. 2019 Sep 4;23(1):108-115. doi: 10.5935/0946-5448.20190019
14. Arianna Di Stadio, Valeria Gambacorta, Stefano de Crescenzo, Angelo Sidoni, Maria Cristina Cristi, Alfredo Di Giovanni, Massimo Maranzano, Giampietro Ricci A Rare Case of Extramedullary Nasal Plasmacytoma in the Left Choana Arising After Polyp Excision: The Role of the Inflammation in Tumor Development. Mol Clin Oncol. 2020 May;12(5):451-455. doi: 10.3892/mco.2020.2007
15. Scarpa A, Ralli M, Di Stadio A et al. Inner ear disorders presenting with air-bone gaps: A review. J Int Adv Otol 2020; 16: 111-116 DOI: 10.5152/iao.2020.7764
16. Arianna Di Stadio, Laura Dipietro, Massimo Ralli, Antonio Greco, Giampietro Ricci, and Evanthia Bernitsas .Clinical and radiological findings of facial paralysis in MS. Mult Scler Relat Disord. 2019 Oct 18;37: 101456. doi: 10.1016/j.msard.2019.101456
17. Di Stadio A, Ralli M, Maranzano M et al. A rare case of asymptomatic adenoid cystic carcinoma of the minor salivary glands in an elderly patient. Ear Nose Throat J. 2019 6:145561319885242. doi: 10.1177/0145561319885242
18. Arianna Di Stadio, Massimo Ralli, Paolo Tropiano, Giovanni Agostini, Giampietro Ricci, Mario Faralli. Head-shaking Nystagmus in the Early Stages of Meniere’s Disease: a pilot study. J Int Adv Otol. 2019 Dec;15(3):425-430. doi: 10.5152/iao.2019.7338.
19. Ralli M, Gilardi A, Di Stadio A, Severini C, Greco A and De Vincentiis M. Hearing Loss and Alzheimer’s: a review. Int Tinnitus J. 2019 Sep 4;23(1):79-85. doi: 10.5935/0946-5448.20190014
20. Massimo Ralli, Arianna Di Stadio, Marco de Vincentiis, Antonio Greco. A rare case of large neck metastasis due to hypopharyngeal cancer. Clin Case Rep. 2019 Nov 23;7(12):2607-2608. doi: 10.1002/ccr3.2503
21. Di Stadio Arianna, Dipietro Laura, Gambacorta Valeria, Della Volpe Antonio, Cristi Maria Cristina, Ricci Giampietro. Can the Jankovic-assessment be used as an alternative to electromyography? A Cross-sectional study on facial dystonia patients treated with Botulinum toxin. Am J Otolaryngol. 2019 Aug 21:102278. doi: 10.1016/j.amjoto.2019.102278.
22. Arianna Di Stadio, Antonio della Volpe, Massimo Ralli, Valeria Gambacorta, Franco Trabalzini,Laura Dipietro and Giampietro Ricci. A minimally invasive endoscope assisted retrosigmoid approach (EAMIRSA) for removal of arachnoid cysts in the internal auditory canal: a step by step description. Braz J Otorhinolaryngol. 2019 Aug 6. pii: S1808-8694(19)30085-0. doi: 10.1016/j.bjorl.2019.06.016.
23. Della Volpe A, Ricci G, Ralli M, Gambacorta V, De Lucia A, Minni A, Pirozzi C, Paccone M, Pastore V, Di Stadio A. The effects of oral supplements with Sambucus nigra, Zinc, Tyndallized Lactobacillus acidophilus (HA122), Arabinogalactans, vitamin D, vitamin E and vitamin C in otitis media with effusion in children: a randomized controlled trial. Eur Rev Med Pharmacol Sci. 2019 Jul;23(14):6360-6370. doi: 10.26355/eurrev_201907_18460
24. Di Stadio A, Dipietro L, Ralli M, Faralli Della Volpe A, Ricci GP, Messineo D. “Loop characteristics and audio-vestibular symptoms or hemifacial spasm: is there a correlation?” A multiplanar MRI study. Eur Radiol. 2020 Jan;30(1):99-109. doi: 10.1007/s00330-019-06309-2.
25. Lucia Longo, Arianna Di Stadio, Massimo Ralli, Ilaria Marinucci, Giovanni Ruoppolo, Laura Dipietro, Antonio Greco. Changes in voice features in professional musician-singers performing with and without a musical instrument: the effect of body posture. Folia Phoniatr Logop. 2019 Jul 15:7. doi: 10.1159/000501202.
26. Arianna Di Stadio, Antonio della Volpe, Massimo Ralli, Ruggero Lapenna, Egisto Molini, Valeria Gambacorta, Giorgia Giommetti , Antonio Greco, Franco Trabalzini and Giampietro Ricci. Sensorineural hearing loss in newborns hospitalized in neonatal intensive care unit: an observationalstudy. Int Tinnitus J. 2019 Jan 1;23(1):31-36. doi: 10.5935/0946-5448.20190006.
27. Di Stadio A, Dipietro L, De Lucia A, Trabalzini F, Ricci G, Martines F, Pastore V, e della VolpeA. E-ABR in patients with cochlear implant: a comparison between patients with malformed cochlea and normal cochlea. J Int Adv Otol. 2019 Aug;15(2):215-221. doi: 10.5152/iao.2019.6251.
28. Di Stadio A, Dipietro L, Ralli M, Greco A, Ricci G, Bernitsas E. The role of vestibular evokedmyogenic potentials in multiple sclerosis-related vertigo. A systematic review of the literature. MultScler Relat Disord. 2018 Dec 24;28: 159-164. doi: 10.1016/j.msard.2018.12.031.
29. Di Stadio A, Bernitsas E. Otolaryngological symptoms and multiple sclerosis: A forgotten and underestimated relationship. Mult Scler Relat Disord. 2019 Jan 3;28:197-198. doi: 10.1016/j.msard.2019.01.010.
30. Di Stadio A., Amadori M., Colangelo R., Falcioni M, Ricci G, Frezza D “Seborrheic keratosis versus squamous carcinoma: the importance of clinical doubt. J Int Adv Otol. 2019 Aug;15(2):326-329. doi: 10.5152/iao.2019.5383.
31. Massimo Ralli, Arianna Di Stadio, Irene Claudia Visconti, Francesca Yoshie Russo, Matteo Saccucci, Maria Paola Balla, Antonio Greco, Marco de Vincentiis. Otolaryngologic Symptoms in Multiple Sclerosis: A Review. InternationalTinnitusJournal.2018;22(2):160-169. DOI: 10.5935/0946 5448.20180027
32. Massimo Ralli, Vittorio D’Aguanno, Marta Altieri, Arianna Di Stadio, Rosaria Turchetta, Marco de Vincentiis, Vittorio Di Piero, Antonio Greco. Ageusia, hyposmia, dizziness and tinnitus as presenting symptoms of multiple sclerosis. InternationalTinnitusJournal.2018;22(2):150-155. DOI: 10.5935/0946-5448.20180025
33. Della Volpe A, Dipietro L, Ricci G, Pastore V, Paccone M, Pirozzi C, Di Stadio A. Pre-treatment with Melamil Tripto® induces sleep in children undergoing Auditory Brain Response (ABR) testing. Int J Pediatr Otorhinolaryngol. 2018 Dec;115:171-174. doi: 10.1016/j.ijporl.2018.10.006.
34. Di Stadio A, Dipietro L, Ricci G, Della Volpe A, Minni A, Greco A, de Vincentiis M, Ralli M.Hearing Loss, Tinnitus, Hyperacusis, and Diplacusis in Professional Musicians: A Systematic Review. Int J Environ Res Public Health. 2018 Sep 26;15(10). pii: E2120. doi: 10.3390/ijerph15102120.
35. Massimo Ralli, Arianna Di Stadio, Armando De Virgilio, Adelchi Croce, Marco de Vincentiis. “Autoimmunity and Otolaryngology Diseases” J Immunol Res. 2018 Oct 4; 2018: 2747904.
36. Di Stadio A and Angelini C “Microglia polarization by mitochondrial metabolism modulation: a therapeutic opportunity in neurodegenerative diseases” Mitochondrion. 2018 Sep 19. pii: S1567-7249(18)30011-4.
37. Di Stadio A, Dipietro L, Toffano R, Burgio F, De Lucia T, Ippolito V, Garofalo S, Ricci GP,Martines F, Trabalzini F , and Della Volpe A. “Working memory function in children with single side deafness using a Bone Anchored Hearing Implant: a case-control study.” Audiol Neurotol 2018; 23: 238–244
38. Di Stadio A, Angelini C. MicroRNAs are appropriate in mitochondrial related hearing loss? Answer to the skepticism. Orphanet J Rare Dis. 2018 Jul 18;13(1):119. doi: 10.1186/s13023018-0865-8.
39. Ralli M,D’Aguanno V, Di Stadio A et al “Audio-vestibular symptoms in systemic autoimmune disease” J Immunol Res. 2018 Aug 19;2018:5798103. doi: 10.1155/2018/5798103. eCollection 2018
40. Di Stadio A, Ralli M, D’Ascanio L, Trabalzini F, Della Volpe A, Ishai R, Ricci GP “Nucleolus vs nucleus count for the identification of spiral ganglion neuron cells in human temporal bones: a histological comparative study.” J Int Adv Otol. 2018 Aug;14(2):181-189.
41. Nordio S, Di Stadio A, Koch I, Stritoni P, Meneghello F, Palmer K. "The correlation between pharyngeal residue, penetration-aspiration, and nutritional modality: A cross-sectional study in patients with neurogenic dysphagia." Acta Otorhinolaryngol Ital. 2019 Mar 25. doi:10.14639/0392-100X-2136.
42. Di Stadio A and Bernitsas E “The origin of facial palsy in Multiple Sclerosis” Otolaryngol Open J 2018; 4(1): e1-e4. doi: 10.17140/OTLOJ-4-e006
43. Nordio S., Bernitsas E, Meneghello F, Dipietro L, Palmer K, Stabile MR, Di Stadio A. “Can expiratory and phonation times be measures of disease severity in patients with Multiple Sclerosis? A pilot study” Mult Scler Relat Disord. 2018 Apr 21;23:27-32. doi: 10.1016/j.msard.2018.04.010.
44. Ricci GP, Di Stadio A, D’Ascanio L, La Penna R, Trabalzini F, Della Volpe A, Magnan J. “Endoscope-assisted retrosigmoid approach in hemifacial spasm: an orl experience.” Braz J Otorhinolaryngol. 2018 May 9. pii: S1808-8694(18)30179-4. doi: 10.1016/j.bjorl.2018.03.015
45. Angelini C and Di Stadio A. Metabolites-Mitochondria-Microglia (Mmma): Therapeutic Stategy for Treatment of Neural Inflammation and Neurodegeneration. J Mol Biomark Diagn 9: 376. doi:10.4172/2155-9929.1000376
46. Di Stadio A, Dipietro L, Ralli M, Meneghello F, Minni A, Greco A, Stabile MR, Bernitsas E. Sudden hearing loss as an early detector of multiple sclerosis: a systematic review. Eur Rev Med Pharmacol Sci. 2018 Jul;22(14):4611-4624. doi: 10.26355/eurrev_201807_15520.
47. Di Stadio A., De Lucia A, Dipietro L, Della Volpe A “ Auditory Brainstem Response and Hearing Loss in MELAS: Post Mortem Analysis of Temporal Bone to Explain Abnormal ABR ”Journal Of Otolaryngology and ENT research Jan 2018, 10 (1): 00301 : DOI 10.15406/joentr.2018.10.00301
48. Di Stadio A, Colangeli R, Dipietro L, Martini A, Parrino D, Nardello E, D’ Avella D, Zanoletti E.“Microsurgical decompression of cochlear nerve for disabling tinnitus by retro-sigmoid approach aresolving and safe procedure. Padua experience” World Neurosurg. 2018 Feb 24. pii: S1878- 8750(18)30378-4. doi: 10.1016/j.wneu.2018.02.105
49. Di Stadio A, Pegoraro V, Giarretta L, Ralli M, Angelini C “Hearing Impairment in MELAS: new prospective in clinical use of microRNA, a systematic review.” Orphanet J Rare Dis. 2018 Feb 21;13(1):35. doi: 10.1186/s13023-018-0770-1
50. Di Stadio, Bernitsas E, Restivo DA, Alfonsi E Marchese-Ragona R “Spasmodic dysphonia in multiple sclerosis treatment with botulinum toxin: a pilot study.” J Voice. 2018 Apr 9. pii: S0892-1997(17)30590-8. doi: 10.1016/j.jvoice.2018.01.002.
51. Di Stadio A, Ralli M. “Inner ear involvement in Multiple Sclerosis: an underestimated condition?” Multiple Sclerosis Journal 1–2 DOI: 10.1177/1352458518750010
52. Ralli M, Greco A, Cianfrone F, Di Stadio A et al. “Somatic Tinnitus” International Tinnitus Journal 2017;21(2):111-120 DOI: 10.5935/0946-5448.20170021
53. Ralli M, Di Stadio A. et Al. “Development of progressive hearing loss and tinnitus in a patient with myasthenia gravis: an overlooked comorbidity?” Hearing, Balance and Communication (IHBC), doi.org/10.1080/21695717.2017.1380968
54. Di Stadio A. “Which factors to induce Hearing loss in Professional Musicians? Extensive literature review and Histopathology Findings can answer it.” Hearing, Balance and Communication (IHBC), 2017 April. 15 (2): 63-71
55. Di Stadio A, Macro C. “Functional results in airflow improvement using a "flip-flap" alar technique: our experience”. Braz J Otorhinolaryngol. 2017 Feb 21. pii: S1808-8694(17)30028-9. doi: 10.1016/j.bjorl.2017.01.006
56. Di Stadio A., Ralli M. “Systemic Lupus Erythematosus (SLE) and Hearing Disorders. Literature review and meta-analysis of clinical and temporal bone findings” J Int Med Res. 2017 Jan 1:300060516688600. doi: 10.1177/0300060516688600
57. Ralli M, Altissimi G, Di Stadio A. et Al. “Relationship between hearing function and myasthenia gravis: a contemporary review” J Int Med Res. 2016 Nov 10. pii: 0300060516672124.
58. Di Stadio A. “Arachnoid Cyst of Internal Auditory Canal.” Accepted Otolaryngology - Open Journal October 2016 2(5): 125-131
59. Di Stadio A. “Ear Keloid Treated with Infiltrated Non-cross-linked Hyaluronic Acid and Cortisone Therapy" In Vivo September-October 2016 30 (5)695-699
60. Di Stadio A. "Which is the Future in Hearing Loss Treatment" Open J. 2016; SE (3): Se1-Se2. doi:10.17140/OTLOJ-SE-3-e001
61. Di Stadio A. “Which is the Best Treatment in Facial Palsy?” Otolaryngol Open J. 2016; SE (2): Se1-Se2. doi: 10.17140/OTLOJ-SE-2-e001
62. Di Stadio A. “Suspect tonsil palatine tumor hides an unrecognized vagal Schwannoma in a patient 75 years old: case report” J Case Report in Medicine, 2016 April; volume 5: 1-3
63. Di Stadio A. “Another scale for the assessment of Facial Paralysis? ADS Scale: our preposition, How to use it.” J Clin Diagn Res. 2015 Dec; 9(12): MC08-11.
64. Di Stadio A., Lazzaro D. “DAAR®: New Digital software for prosody’s study in subject with
65. monolateral cochlear implant” Prevention and research Journal 2015; 4(3): 84-90
66. Di Stadio A. “Eyelid lifting for ectropion and scleral show in facial palsy disease” ORL 2014; 76:329-335
67. Di Stadio A. “Combination of rehabilitation and eye soft surgery thought to reduce eye disease andthe incidence of syncinesia” Italian Journal of Maxillofacial Surgery 2013 Agosto;24(2):69-75
68. Di Stadio A. “New scale for the assessment of facial paralysis: ADS scale” Italian Journal of Maxillofacial Surgery 2013 Agosto;24(2):81-7
69. Di Stadio A., D. Lazzaro “DAAR: New Software for Studying Voice Parameters in People with Cochlear Implant” CMNSEM, Vol 3 No 4: 103-109 May 2012
70. Di Stadio A et Al “Vagal Schwannoma that simulates a pharyngeal tumor: case report” Il Valsalva 3/ 4, 2006; 82:95-97
71. Di Stadio A et Al. “The treatment of facial palsy in association with the Kabat rehabilitation therapy and the lower eyelid lifting to reduce the recovery time.” Il Valsalva 83- ¾-2007;51-53
72. Spahiu I, A. Di Stadio A et Al. “Nose functionality disease after rhinoseptoplasty” Il Valsalva 1/2-2007; 83:35-37
73. Di Stadio A “Association between Kabat Therapy and Soft Surgery of the Eye for a Rapid Resolution of Facial Palsy” Skull Base 2006; 16 - A002 DOI: 10.1055/s-2006-958536
74. Monini S, Di Stadio A. et Al “Silent reflux: ex adjuvantibus criteria for diagnosis and treatment of laryngeal disorders” Acta Oto-Laryngologica 2006 Aug;126(8):866-71
75. Barbara M, Monini S., Buffoni A., Di Stadio A., Filipo R. et al: “Early rehabilitation of facial nerve deficit after acoustic neuroma surgery” Acta Otolaringol.2003 Oct; 123(88): 932-5
76. Monini, S, Barbara, M, Parisi, L, Bertoli, GA, Buffoni, A, Di Stadio, A, Bernardeschi, D; Filipo, R.EMG vs Objective Staging during Physical Rehabilitation after Peripheral Facial Nerve Deficit Otology & Neurotology: 2002 - Volume 23 - Issue - p S92
77. Saponara M., Di Stadio A. et al “Morphological and functional alteration of facial muscle and temporo mandibular joint due to OSAS”; Nuova rivista Di Neurologia 11(1); Feb. 2001:14-16
78. Di Stadio A.et al “OSAS: cephalometric and polisomnography variation in patients subject to maxillo-mandibular osteotomies.” Il Valsalva 1999; 75:47-53
79. Schettino R., Di Stadio A., Saponara M.et al. “Syrinx in OSAS patients” Il Valsalva 1998;74:161-166

Non Peer-Reviewed publications (BOOK Chapter)

• Ricci G, Di Stadio A, della Volpe A. Congenital Aural Atresia: hearing rehabilitation by bone anchored hearing implant (BAHI) in the book “Advance in rehabilitation of hearing loss”.
• 2019 Di Stadio A, De Lucia A, Ippolito V and Della Volpe A “Single Side Deafness in children: up to date” in the book “Sensorineural Hearing Loss: Pathophysiology, Diagnosis and Treatment”
• 2015 Di Stadio A. “Speedy and Easy technique in facial palsy Surgery” in the book “Facial Paralysis: Clinical Features, Management and Outcomes”.
• 2000 Mattioni A, Rinaldi M., Di Stadio A., Germano F., Sitzia E. “Auditory evoked potential” in the book “Hearing loss: medical-legal aspect”.

Clinical Guidelines and Reports

Authorization of clinical protocols addressed to “Receivers human body products” and to “Innovative therapies” like member of France National Agency for Health safe (ANSM).

Abstract and Poster Presentation at professional Meeting

Published Abstract

 “Microglia in Meniere’s syndrome” 7th International Symposium on Meniere’s disease and Inner Ear Disorders, Rome Italy, 17-20 2015

“New philisophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA.

“My face Complex® my idea of antiage supplement” and “New philosophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA.

Monini, S; Barbara, M; Parisi, L; Bertoli, G A; Buffoni, A; Di Stadio, A; Bernardeschi, D; Filipo, R EMG vs Objective Staging during Physical Rehabilitation after Peripheral Facial Nerve Deficit Otology & Neurotology: 2002 - Volume 23 - Issue - p S92

A Di Stadio “Association between Kabat Therapy and Soft Surgery of the Eye for a Rapid Resolution of Facial Palsy” Skull Base 2006; 16 - A002 DOI: 10.1055/s-2006-958536

Poster Presentation

“The role of microRNA in mitochondrial disease” SIN 50° National meeting, 12-15 October 2019, Bologna, Italy

 “Adhesive Anchored Prosthesis (AAP) may improve memory function in patients with Single Side Hearing Loss (SSHL): a pilot study” ESPO 2018, 2-5 June, Stoccolm, Sweden

“Difensil IMMUNO® (DI) to reduce the frequency of Upper Airways Inflammation (UAI) and otitis media acute (OMA) in children” ESPO 2018, 2-5 June, Stoccolm, Sweden

“Mitochondrial disease and Sensorineural Hearing Loss”. VII National Congress on Mitochondrial Disease, 22-24 September 2017, Milan Italy

“Microglia in Meniere’s syndrome” 7th International Symposium on Meniere’s disease and Inner Ear Disorders, Rome Italy, 17-20 2015

“Association of physical rehabilitation and soft surgery to reduce the incidence of sincinesia” 12th International Facial Nerve Symposium Boston MA USA 28/06/2013- 1/07/2013

Podium Presentation (not published abstract)

1. “Sudden hearing loss and multiple Sclerosis”, Neuroscience meeting 2019, London 12 April 2019,University College London (UCL).
2. “Subclinical cochlear dysfunction in newly diagnosed relapsing- remitting multiple sclerosis” Inner Ear Biology international congress, Padua Italy 7-10 September 2019
3. “Loop characteristics may be predictive of the compressive effects on the nerves in the Internal Auditory Canal?” SIO, National Otolaryngology Symposium, Naples 16-19 May 2018
4. “Spiral Ganglions and word discrimination. What’s true?” CHDEAF, VII International Symposium on Childhood Deafness, Naples Italy 16-18 November 2017
5. “ADS scale a valid alternative to other facial assessments in facial palsy disorders” CHDEAF ,VII International Symposium on Childhood Deafness, Naples Italy 16-18 November 2017
6. 28/03/2017 “White Matter Hyperintensities and SNHL: can we define a central SNHL”, Workshop Audiology, Clermont Ferrand, France
7. 16/02/2017 “Loop of Internal Auditory Canal, anatomical variation or disease?”. CORLAP, Padova, Italy
8. 02/29/2016 “The genetic approach to anti-aging” Imcas 2016, Paris France
9. 06/24/2015 “My face Complex® my idea of anti-age supplement” and “New philosophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA.
10. 06/23/2015 “New philosophy approach at cosmetic procedure”, Cosmetology 2015, Philadelphia, USA. 
11. 12th International Facial Nerve Symposium Boston 28/06/2013- 1/07/2013 “New scale for assessment of facial paralysis: ADS scale” A. Di Stadio. 
12. 34th Annual conference of the European academy of Facial Plastic Surgery-1-4 September 2011, Bruges “New scale for assessment of facial paralysis: ADS scale” A. Di Stadio 
13. 35eme Congres l’association Française des chirurgiens maxillo-faciaux, Paris 29/03/2010 - 31/03/2010 « Eyes soft surgery associated with Kabat therapy for reduction of eye disease and syncinesia incidence in facial palsy » A. Di Stadio. 
14. 93 National Congress SIOeChCF, 31 Maggio-3 Giugno 2006 Bologna: “The combination of weight implantation and medial canthoplasty for early treatment of facial palsy” A. Di Stadio, G.A. Bertoli, E. De Seta, R. Filipo et al. 
15. 8th European Symposium on Pediatric Cochlear Implantation, 25-28 March 2006 Venezia: “New Digital Software for Vocal Parameters Study in Children with Cochlear Implants: Preliminary Results” A.Di Stadio, A. Musacchio,  R. Filipo et Al. 
16. X International Facial Nerve Symposium, 4-7 September 2005: “The combination of weight implantation and medial canthoplasty for early treatment of facial palsy” G.A. Bertoli, A. Di Stadio, R. Filipo et al. 
17. “Facial Nerve Paralysis”, Team Facial Plastic Surgery Congress Roma Congress, Roma 28/1/2005: “Rehabilitation of Facial Palsy” A. Di Stadio. ROMA OSAS 2000 Roma 1-4 March 2000: “Maxillo-facial abnormalities causes or outcomes of Osas?” Di Stadio et al. 
18. “Facial Nerve Paralysis”,Team Facial Plastic Surgery Congress Roma 26/11/2004: “Facial Nerve paralysis: clinical staging and etiology” A. Di Stadio. 
19. V European Congress Of Oto-Rhino-Laryngology Head and Neck Surgery, Rodi 11-16 September 2004: “Silent (E)LPR” S. Monini, A. Di Stadio, F. Ronchetti, M. Barbara 
20. ROMA OSAS 2000 Roma 1-4 March 2000: “Tonsil volume reduction with coblation” M. Saponara, M. Fabiani, A. Di Stadio et al. 
21. ROMA OSAS 2000 Roma 1-4 March 2000: “Functional endoscopic sinus surgery (FESS) in the treatment of nasal obstruction by involvement of middle meatal area” V. Pizzichetta, A. Mattioni, A. Di Stadio et al.