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Research Interests
- Cancer Biology
- Molecular Pharmaceutics
- Molecular Medicine
- Stem Cells and Regenerative Medicine
Education
Sep 2014- Sep 2017 |
- Master of Science in Cell and Molecular biology
Department of Biology, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran.
Thesis Title: Discovering the structure-activity relationships of different O-prenylated coumarin derivatives as effective anticancer agents in human cervical cancer cells.
Supervisors: Prof. Maryam M. Matin and Prof. Ahmad Reza Bahrami
GPA: 18.41out of 20. |
Sep 2009- Sep 2013 |
- Bachelor of Science in Cell and Molecular biology
Department of Biology, Faculty of Science, Guilan University, Rasht, Iran.
GPA: 16.16 out of 20. |
Research Experiences
Sep 2019-Present |
Research assistant in Stem cells and Regenerative Medicine Research Lab, Mashhad University of Medical Science, Iran
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Sep 2017- Present |
Research assistant in the Cell, Tissue andCancer Research Lab,
Ferdowsi University of Mashhad, Iran.
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Publications
Ebrahim H. Maleki, Ahmad Reza Bahrami, Hamid Sadeghian, Maryam M. Matin
Discovering the structure-activity relationships of different O-prenylated coumarin derivatives as effective anticancer agents in human cervical cancer cells.
Toxicol In Vitro; 63: 104745, 2020 Mar
Seddigheh Sheikhi-Mohammareh, Ali Shiri, Ebrahim H. Maleki, Hamid Beyzaei, Parviz Baranipour, Maryam Matin, Fatemeh Oroojalian, Toktam Memariani
Synthesis of various derivatives of [1,3]selenazolo[4,5-d]pyrimidine as a novel heterocyclic system exploited as anticancer, antibacterial, and antifungal agents.
ChemistrySelect; 5: 32: 10060, 2020 Aug.
Ebrahim H. Maleki, Maryam M. Matin, Naisana S. Asli
Cell cycle heterogeneity as a key element in cancer resistance to therapy
Conference and Seminars
2018 |
- Ebrahim H. Maleki, Ahmad Reza Bahrami, Hamid Sadeghian, Maryam M. Matin
Poster presentation entitled ‘Investigating Cytotoxic and Anticancer Properties of Coumarin Derivatives Contain Geranyl Groups at Different Position on Cervical Cancer.
3rd National Festival and International Congress on Stem Cells and Regenerative Medicine, Iran
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2018 |
- Alireza sharafshah, Ebrahim H. Maleki, Parvaneh keshavarz.
Poster presentation entitled ‘In silico Studies of rs1799971(A1188G) OPRM1gene Structural Variant Binding to Morphine as an Opioid Addiction Saubstrate’.
2nd International and 10th Iranian Neurogenetic Congress |
2017 |
- Ebrahim H. Maleki, Ahmad Reza Bahrami, Hamid Sadeghian, Maryam M. Matin.
Poster presentation entitled ‘Investigating Cytotoxic and Anticancer Properties of Auraptene and Several of Its Derivatives on Cervical Cancer
in Vitro.
2nd international congress on Biotechnology, Karaj, Iran
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2017 |
- Ebrahim H. Maleki, Ahmad Reza Bahrami, Hamid Sadeghian, Maryam M. Matin
Oral presentation entitled ‘Investigating Cytotoxic and Anticancer Properties of Coumarin Derivatives Contain Prenyl Groups at Difference Position on Cervical Cancer’.
1st National Congress on Herbal Medicine Biotechnology, Zanjan, Iran
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2015 |
- Danial Babaki, Ebrahim H. Maleki, Mahdi Gholami.
Poster presentation entitled ‘Use of Amnion as an Allograft Material in Vestibuloplasty’.
International Congress on Stem Cells and Regenerative Medicine,
Mashhad, Iran |
Teaching Experiences
2019-present |
- University lecturer of Basic Genetic, Molecular Biology, Genetics of Prokaryotes, Genetic Engineering for undergraduate students
Kheradgerayan Motahar Institute of Higher Education, Iran
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2019-2020
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- University lecturer of Practical Cell Biology for undergraduate students
Ferdowsi University of Mashhad, Iran |
2016-present |
- Cell Culturing Workshop main instructor
Ferdowsi University of Mashhad, Iran |
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2016-present |
- Drug Screening and MTT Workshop main instructor
Ferdowsi University of Mashhad, Iran |
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2016-present |
- Instructor of university students for National Olympiad of Stem Cells and Regenerative Medicine(Teaching Advanced Cell Biology and Animal Cell and Tissue Culture)
Ferdowsi University of Mashhad, Iran |
2015-present |
- Instructor of university students for National Biology Olympiad (Teaching Cell and Molecular Biology)
Ferdowsi University of Mashhad, Iran |
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2012-present |
- Biology and Stem Cells and Regenerative Medicine Olympiad instructor
Nodet (National Organization for Development of Exceptional Talents) High School, Iran
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Awards and Honors
2017 |
- The Ferdowsi University of Mashhad Award for being ranked as second among all M.Sc. graduated students in the Department of Biology
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2015- 2019 |
- Director and Chair at Interdisciplinary Student Scientific Association for Cancer Prevention of Ferdowsi University of Mashhad, Iran
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2014 |
- Ranked within top 0.3% of participants in the National Entrance exam of Master’s Degree by Iran Ministry of Education
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2009 |
- Ranked within top 0.8% of participants in the National Entrance exam of
Bachelor’s Degree by Iran Ministry of Education
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2005 |
- Officially Acknowledged by the Ministry of Education for winning the Administrative Student Committee Election.
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2002 |
- Awarded appreciation diploma, Provincial Mathematics Olympiad (Among approximately 2600 participants and after three rounds of examinations including theoretical and practical evaluations).
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Language
- Persian: Native
- English: Academic IELTS test:
- Listening: C1, Reading: C1, Speaking: B2, Writing: B2
Professional Skills
Cell Biology |
- Normal, Cancerous Cell, and Stem Cell Culture (2D/3D as well as Single/Co-culture) and Differentiation, Cell Transfection, Apoptosis Detection, Drug screening
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Molecular Biology |
- RNA Transcription and labeled antisense mRNA probes, Nucleic acid (DNA, RNA, miRNA, and viral RNA) extraction from various sources( including whole blood, serum, saliva, cell line, and tissue sections), Gene Cloning, RT/Q-PCR, Primer Design
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Protein Biochemistry |
- Western Blotting, Gene Expression (Prokaryote & Eukaryote systems), Protein Extraction
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Immunology |
- Immunohistochemistry, ELISA, MTT
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Other |
- Microscopy, Laboratory Animal Handling (BALB/c and C57BL/6), Flow Cytometry
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Computer Skills
- Programming & Statistics:
- GraphPad Prism (Advanced)
- R programming, Python programming, , Linux (Basic)
Extra-Curricular Activities
Apr 2019 |
- Workshop of Next Generation Sequencing Data Analysis
Department of Stem cells and Regenerative Medicine, ACECR Khorasan Razavi, Iran
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Apr 2018 |
- Workshop of the Principles of Statistical Analyses in Biology with R (30 h)
Ferdowsi University of Mashhad, Iran
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Oct 2017 |
- Workshop of Bases of Biostatistics (35 h)
Ferdowsi University of Mashhad, Iran
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May 2015 |
- Workshop of Theoretical and Practical Principles of Polymerase Chain Reaction and Other Molecular Technics
The Research Institute of Biotechnology, Ferdowsi University of Mashhad, Iran
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Aug 2015 |
- Workshop of Isolation, Purification, and Culturing of Stem Cells from Various References.
The Research Institute of Biotechnology, Mashhad, Iran |
Dec 2015 |
- Workshop of Drug Screening and Proliferation and Apoptosis Assays
The Research Institute of Biotechnology, Mashhad, Iran |
Attendance in Congress
Sep 2018 |
- Member of Student Executive Committee
The 2nd Nastaran Cancer Symposium, Mashhad, Iran |
May 2017 |
- Member of Student Executive Committee
The 2nd International Congress on Stem Cells and Regenerative Medicine, Mashhad, Iran |
Sep 2016 |
- Member of Student Executive Committee
The 1st International Nastaran Cancer Symposium, Mashhad, Iran |
May 2015 |
- Member of Student Executive Committee
The 1st International Congress on Stem Cells and Regenerative Medicine, Mashhad, Iran |
References
- Prof. Maryam M.Matin
- Dr. Naisana S. Asli
- Faculty of Medicine and Health, University of Sydney, Australia
- Email: [email protected]
- Prof. Ahmad Reza Bahrami
- Assistant Prof. Hamid Sadeghian
- School of Paramedical Sciences, Mashhad University of Medical Sciences(MUMS),
Iran - Email: [email protected]
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