MA

Mazdak Ganjalikhani hakemi




Resume



First Name: Mazdak


Last Name: Ganjalikhani Hakemi


Gendre/Martial Status: Male/Married/2 kids


Date/Place of Birth: Feb 15, 1976. Tehran, Iran


Academic Rank: Ph.D. in Immunology (Molecular Immunology)


Academic Position: Associate Professor


H-index: 21 (Google Scholar)


Address: Immunilogy Dept., Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.


Telephone: +98-31-37929082


Mobile: +98-913-412-7287


Fax: +98-31-37929031


E-mail: [email protected]






Educations:Academic Preparations



  • Ph.D. Immunology,    
    Grade: 18.82/20, Isfahan University of Medical Sciences, Isfahan, Iran 2011         
  • M.Sc.       Immunology,          
    Grade: 18.23/20, Tehran University of Medical Sciences, Tehran, Iran 2002
  • B.Sc.         Laboratory sciences, Grade: 18.08/20,
    Iran University of Medical Sciences, Tehran, Iran 1999




Dissertations:



  • PhD thesis:

Invitro analysis of siRNA mediated silencing of RORC2 gene expression and its effect on IL17 production by human Th17 cells.


Degree: Excellent, 19.96


Supervisors: A. Rezaei, PhD, K. Ghaedi, PhD.


Advisors:A. R. Andalib, PhD, M. Hosseini, PhD


Isfahan University of Medical Sciences, Isfahan, Iran 2011



  • M.Sc. Thesis:

Comparison of validity of microlymphocytotoxicity and flow cytometry methods with PCR for HLA-B27 antigen typing in Iranian patients with ankylosing spondylitis.


Degree: Excellent, 19.00


Supervisors: M.H. Nicknam, M.D, PhD, A.R. Jamshidi, M.D.


Advisors: B. Nikbin, M.D, PhD, A. Amirkhani, PhD,F. Khosravi, M.Sc.


Tehran University of Medical Sciences, Tehran, Iran 2001





Honors & Awards:



  • 1st rank in Ph.D.program in Immunology. Isfahan University of Medical Sciences, Faculty of Medicine, Iran, Jul 2011.
  • 3.5 years scholarship winner for PhD program. Isfahan University of Medical Sciences, Iran, Mar 2008.
  • Winner of the bestbook of 2004 for translation of “Cellular & Molecular Immunology". Iran, 2004.
  • 1st rank in M.Sc.program in Immunology. Tehran University of Medical Sciences, Faculty of Medicine, Iran, Jan 2001.
  • 3rd rank in M.Sc entrance examination.Ministry of Health and Medical Education, Iran, 1999.




POSITIONS HELD



  1. Head of the Department of Laboratory Sciences, Faculty of Medicine, Isfahan University of Medical Sciences. Since Aug 2020. Isfahan, Iran.
  2. Associate professor in Immunoplogy Department, Faculty of Medicine, Isfahan University of Medical Sciences. Since Jul 2017. Isfahan, Iran.
  3. Assistant professor in Immunoplogy Department, Faculty of Medicine, Isfahan University of Medical Sciences. Aug 2011 to Jul 2017. Isfahan, Iran.
  4. Advisory Board Member of Post Graduate Education Commettee. Faculty of Medicine, Isfahan University of Medical Sciences. Jan 2016 to Sep 2019. Isfahan, Iran.
  5. Deputy of Education of Immunology Department, Faculty of Medicine, 
    Isfahan University of Medical Sciences. Since Jun 2014. Isfahan, Iran.
  6. Head and Director Manager of Dr. Hakemi Medical Diagnostics Laboratory. Since Appril 2019. Isfahan, Iran.
  7. Head of “Cellular & Molecular Immunology Research Center”. Isfahan University of Medical Sciences. Jul 2013 to Jul 2015. Isfahan, Iran.
  8. Researcher (sabbatical) in Center for Noanoscience, Pharmaceutical Biotechnology, Ludwig-Maximillians University. 2010-2011. Munich, Germany.
  9. Supervisor of Quality Control Dept., Cinnagen Co., Simindasht Industrial area, 2004-2006.Tehran, Iran.


PROFESSIONAL MEMBERSHIPS



  1. Guest Editor in journal of Frontiers in Oncology for the section of
    Hematologic Malignancies in 2021.
  2. Editorial Board Member of Archives of Immunology and Allergy Research Since May 2018.
  3. Editorial Board Member of Journal of Hematology and Oncology Research Since Dec 2017.
  4. Editorial Board Member of EMS Journal of Immunology & Allergy
    Since Aug 2017.
  5. Editorial Board Member of SM Journal of Hematology & Multiple Myeloma
    Since Aug 2017.
  6. Editorial Board Member of Journal of Immune Disorders & Therapy
    Since July 2017.
  7. Editorial Board Member of Journal of Immunology Forecast
    Since July 2017.
  8. Editorial Board Member of SMNeurodegenerative Disorders
    Since July 2017.
  9. Editorial Board Member of SRL Multiple Sclerosis
    Since May 2017.
  10. Editorial Board Member of International Journal of Clinical Oncology & Cancer Research
    Since April 2017.
  11. Editorial Board Member of
    International Journal of Multiple Sclerosis and Related Disorders
    Since April 2017.
  12. Editorial Board Member of
    Annals of Multiple Sclerosis and Related Disorders. Since Mar 2017.
  13. Editorial Board Member of
    Allergy & Immunology Case Reports Since Mar 2017.
  14. Editorial Board Member of
    Annals of Clinical and Experimental Immunology Since Mar 2017.
  15. Editorial Board Member of
    SM Journal of Autoimmune Diseases Since Mar 2017.
  16. Editorial Board Member of
    Insights in Pediatric Research Since Dec 2016.
  17. Editorial Board Member of Journal of Immunology Research and Clinical Applications (JIRCA) Since Sep 2016.
  18. Editorial Board Member of
    Journal of Immunological Diseases, Disorders and their Prevention (AJIV) Since June 2016.
  19. Editorial Board Member of
    ARC Journals of Immunology and Vaccines (AJIV). Since Nov 2015.
  20. Iranian Authors, Journalist and Artists Support Credit Fund. Ministry of Ershad-e Eslami. Iran, Since 2006.
  21. European Academy of Allergology & Clinical Immunology (EAACI). Sweden, 2006 -11.
  22. Member of editorial board and incharge of medical news section in Journal of
    Ketab-e Hayyan. 2003-2004. Tehran, Iran.
  23. Iranian society of Asthma & Allergy (ISAA). Iran, 2002-4.
  24. Member of Organizing Committee of the
    6thInternational Congress of Immunology and Allergy
    2002, Tehran, Iran.
  25. Iranian society for Immunology & Allergy (ISIA). Iran, Since 2000.



PUBLICATIONS



  • BOOKS:


  1. Association of HLA and HLA-Related Genes with Ankylosing Spondylitis. M Ganjalikhani Hakemi - Ankylosing Spondylitis-Axial Spondyloarthritis, Springer, Singapore, 2022
  2. Association of Non-HLA Genes with Ankylosing Spondylitis. M Rahmati, M Ganjalikhani Hakemi - Ankylosing Spondylitis-Axial Spondyloarthritis, Springer, Singapore, 2022
  3. “Textbook of Immunology by Intimate Words”. Jamee Negar Pub. 2019.
  4. “IMMUNOCHEMISTRY: A BASIC AND PRACTICAL GUIDEBOOK”.  Jamee Negar Pub. 2015.
  5. “EXPERIMENTAL METHODS IN IMMUNOLOGY”. Jamee Negar Pub. 2014.
  6. Translation of“CELLULAR AND MOLECULAR IMMUNOLOGY”. Abul K. Abbas, et al. 7th edition. Hayyan Pub. 2012.
  7. “AN OVERVIEW ON ORGANIZATION AND FUNCTION OF IMMUNE SYSTEM”.Arad Ketab Pub. 2010
  8. "A SUMMARY OF CELLULAR AND MOLECULAR IMMUNOLOGY". Hayyan Pub. 2008
  9. Translation of“BASIC IMMUNOLOGY”. Abul K. Abbas, et al. 3nd edition.
    Hayyan Pub. 2008
  10. Translation of"ALLERGY”. Nelson. 18th edition. Hayyan Pub. 2008
  11. Translation of"RHEUMATOLOGIC DISORDERS”. Nelson. 18th edition. Hayyan Pub. 2008
  12. Translation of“IMMUNOLOGY" Nelson. 18th edition. Hayyan Pub. 2008
  13. Translation of“CELLULAR AND MOLECULAR IMMUNOLOGY”. Abul K. Abbas, et al. 6th edition. Hayyan Pub. 2007.
  14. Translation of“BASIC IMMUNOLOGY”. Abul K. Abbas, et al. 2nd edition.Hayyan Pub. 2004.
  15. Translation of“IMMUNOLOGY, ALLERGY AND RHEUMATOLOGY”. Nelson. 17th edition.Hayyan Pub. 2004.
  16. Translation of“CELLULAR AND MOLECULAR IMMUNOLOGY”. Abul K. Abbas, et al. 5th edition. Hayyan Pub. 2003.
  17. Translation of“IMMUNOLOGY A SHORT COURSE”. Eli Benjamin, et al. Rastan Pub. 2001.
  18. Translation of“MEDICAL IMMUNOLOGY”. Daniel P Stites, et al. 10th edition.Rastan Pub. 2001.
  19. Translation of“IMMUNE SYSTEM”. Peter Parham. 1st edition. Vefagh Pub. 2000 .




  • SCIENTIFIC PAPERS


  1. Soltani M, Zhao Y, Xia Z, Ganjalikhani Hakemi M, Bazhin AV. The importance of cellular metabolic pathways in pathogenesis and selective treatments of hematological malignancies. Frontiers in Oncology. 2021; 11:767026. 
    DOI: 10.3389/fonc.2021.767026.
  2. Shapoorian H, Zalpoor H, Ganjalikhani-Hakemi M. The correlation between Flt3-ITD mutation in dendritic cells with TIM-3 expression in Acute myeloid leukemia. Blood Science. 2021; 3: 132-135. DOI: 10.1097/BS9.0000000000000092
  3. Peyman A, Namgar M, Feizi A, Ganjalikhani-Hakemi M, Nasab FH, Pourazizi M. Interleukin-6 and tumor necrosis factor-α levels in tear film of Keratoconus patients. Journal of Research in Medical Sciences. 2021;26(1):75-79.
     
  4. Rezaei M, Tan J, Zeng C, Li Y, Ganjalikhani-Hakemi M. TIM-3 and Leukemia; The Immune Response and Beyond Frontiers in Oncology. 2021; 11:753677.
     DOI: 10.3389/fonc.2021.753677.
  5. Bidram M, Zhao Y, Shebardina NG, Baldin AV, Bazhin AV, Ganjalikhany MR, ...,
    Ganjalikhani-Hakemi M. mRNA-based cancer vaccine: A therapeutic strategy for the treatment of melanoma patients. Vaccines. 2021; 9: 1060-1093. DOI: 10.3390/vaccines9101060
  6. Dehbashi M, Hojati Z, Motovali-bashi M, Cho WC, Shimosaka A, Ganjalikhani-Hakemi M. The bioinformatic analyses of OIP5-AS1 for CD25 expression. Gene Reports. 2021;24:101223. DOI: 10.1016/j.genrep.2021.101223
  7. Baghi M, Yadegari E, Peymani M, Ganjalikhani-Hakemi M, Salari M, Nasr-esfahani M, et al. MiR-193b deregulation is associated with Parkinson's disease. Journal of Cellular and Molecular Medicine. 2021;25:6348–6360. DOI: 10.1111/jcmm.16612
  8. Fathi F, Sanei B, Ganjalikhani Hakemi M, Saidi RF, Rezaei A. Liver Resection Promotes (Regulates) Proinflammatory Cytokines in Patients with Hepatocellular Carcinoma. Canadian Journal of Gastroenterology and Hepatology. 2021; DOI: 10.1155/2021/5593655.
  9. Dehbashi M, Hojati Z, Motovali-bashi M, Ganjalikhany MR, Cho WC, Shimosaka A, …,
    Ganjalikhani-Hakemi M. A novel CAR expressing NK cell targeting CD25 with the prospect of overcoming immune escape mechanism in cancers. Frontiers in Oncology. 2021; DOI: 10.3389/fonc.2021.649710. 
  10. Etemadifar M, Sedaghat N, Aghababaee A, Kargaran PK, Maracy MR, Ganjalikhani-Hakemi M, et al. COVID-19 and the Risk of Relapse in Multiple Sclerosis Patients: A Fight with No Bystander Effect? Multiple Sclerosis and Related Disorders. 2021;51:102915.
  11. Aria H, Ghaedrahmati F, Ganjalikhani-Hakemi M. Cutting Edge: Metabolic Immune Reprogramming, Reactive Oxygen Species and Cancer. Journal of Cellular Physiology. 2021; DOI: 10.1002/jcp.30303.
  12. Katebi A, Varshochian R, Riazi-radd F, Ganjalikhani-Hakemia M, Ajdary S. Combinatorial delivery of antigen and TLR agonists via PLGA nanoparticles modulates Leishmania major-infected-macrophages activation. Biomedicine & Pharmacotherapy. 2021;137:111276.
  13. Navabi P, Ganjalikhany MR, Jafari S, Dehbashi M, Ganjalikhani-Hakemi M. Designing and optimization of a single-chain fragment variable (scFv) antibody against IL2Rα (CD25): An in silico and in vitro study. Iranian Journal of Basic Medical Sciences. 2021;24(3):360-8.
  14. Dehbashi M, Hojati Z, Motovali-bashi M, Ganjalikhani-Hakemi M, Shimosaka A, Cho WC. Computational study for suppression of CD25/IL-2 interaction. Biological Chemistry. 2021;402(2):167-78.
  15. Etemadifar M, Parsa Abhari A, Sabeti F, Ganjalikhani-Hakemi M, Salari M, Hashemi F, et al. “NMDA receptor spectrum disorder” in the differential diagnosis of demyelinating disorders of the CNS: optic neuritis and myelitis. Neurological Sciences. 2021;42(1):151-7.
  16. Boshra A, Alsahebfosoul F, Ganjalikhani-Hakemi M. Evaluation of the effect of Epigallocatechin-3-gallate (EGCG) on HIF-1a protein and RORC gene expression in peripheral blood mononuclear cells of patients with multiple sclerosis. Basic and Clinical Neuroscience. 2021; 12(4): 1-16; DOI: 10.32598/bcn.
    2021.2252.1.
  17. Shams MH, Assarehzadegan MA, Eskandari N, Masjedi M, Kheirandish F, Ghasemi R,
    Ganjalikhani Hakemi M, et al. Molecular and Immunochemical Characterization of Pop n 2: A New Allergen of Populus nigra Pollen. Clinical and Experimental Allergy. 2020; DOI: 10.1111/cea.13789.
  18. Shams M-H, Jafari R, Eskandari N, Masjedi M, Kheirandish F, Ganjalikhani Hakemi M, et al. Anti-allergic effects of vitamin E in allergic diseases: An updated review. International Immunopharmacology. 2020; DOI: 10.1016/j.intimp.2020.107196.
  19. , Jafarinia M, Azizi M, Rezaeepoor M, Isayev O, Bazhin AV. The Role of TIM-3 in Hepatocellular Carcinoma: A Promising Target for Immunotherapy? Frontiers in Oncology. 2020; DOI: 10.3389/fonc.2020.601661.
  20. Jafarinia M, Alsahebfosoul F, Salehi H, Eskandari N, Azimzadeh M, Mahmoodi M, Asgari S,
    Ganjalikhani-Hakemi M. Therapeutic effects of extracellular vesicles from human adipose-derived mesenchymal stem cells on chronic experimental autoimmune encephalomyelitis. Journal of Cellular Physiology. 2020;235(11):8779-90.
  21. Ashja-Arvan M, Dehbashi M, Eslami A, Salehi H, Yoosefi M, Ganjalikhani-Hakemi M. Impact of IFN-β and LIF overexpression in human adipose-derived stem cells (hADSCs) properties. Journal of Cellular Physiology. 2020;235(11):8736-46.
  22. Jafarinia M, Alsahebfosoul F, Salehi H, Eskandari N, Ganjalikhani-Hakemi M. Mesenchymal Stem Cell-Derived Exosomes: A novel cell-free therapy. Immunological Investigations. 2020;49(7):758-80.
  23. Farrokhi S, Abbasirad F, Esmaeil N, Sherkat R, Yazdani R, Afshar-Ghasemlou S, …,
    Ganjalikhani-Hakemi M. Increased Expression of B lymphocyte Induced Maturation Protein 1 (BLIMP1) in Patients with Common Variable Immunodeficiency (CVID). Iranian Journal of Asthma Allergy and Immunology. 2020;19(4):437-46.
  24. Eslami A, Dehbashi M, Ashja-Arvan M, Salehi H, Azimzadeh M, Ganjalikhani-Hakemi M. Assessment of ability of human adipose derived stem cells for long term overexpression of IL-11 and IL-13 as therapeutic cytokines. Cytotechnology 2020;72(5):773-84.
  25. Soltani M, Rezaei M, Ganjalikhani Hakemi M. Common Variable Immunodeficiency (CVID) and Autoimmunity. Immunology and Genetics Journal. 2020;3(2):12-28.
  26. Azimzadeh M, Mahmoodi M, Kazemi M, Ganjalikhani hakemi M, Jafarinia M, Eslami A, et al. The immunoregulatory and neuroprotective effects of human adipose derived stem cells overexpressing IL-11 and IL-13 in the experimental autoimmune encephalomyelitis mice. International Immunopharmacology. 2020; DOI: 10.1016/j.intimp.2020.106808.
  27. Ostadi V, Sherkat R, Migaud M, Modaressadeghi S-M, Casanova J-L, Puel A, …,
    Ganjalikhani-Hakemi M    . Functional analysis of two STAT1 gain-of-function mutations in two Iranian families with autosomal dominant chronic mucocutaneous candidiasis. Medical Mycology. Accepted in May 2020.
  28. Boshra A, Alsahebfosoul F, Ganjalikhani-Hakemi M. Evaluation of the effect of Epigallocatechin-3-gallate (EGCG) on HIF-1a protein and RORC gene expression in peripheral blood mononuclear cells of patients with multiple sclerosis. Basic and Clinical Neuroscience. Accepted at 3rd Apr 2020.
  29. Azimi M, Eskandarian A, Ganjalikhani-Hakemi M, Zohrabi T. Knocking down of the DHFR-TS gene in Toxoplasma gondii using siRNA and assessing the subsecuences on Toxoplasmosis in mice. Acta Tropica. Accepted at 1st Apr 2020.
  30. Jafarinia M, Alsahebfosoul F, Salehi H, Eskandari N, Azimzadeh M, Mahmoodi M, …,
    Ganjalikhani-Hakemi M. Therapeutic effects of extracellular vesicles from human adipose-derived mesenchymal stem cells on chronic experimental autoimmune encephalomyelitis. Journal of Cellular Physiology. Apr 2020, DOI: 10.1002/jcp.29721 
  31. Ashja-Arvan M, Dehbashi M, Eslami A, Salehi H, Yoosefi M, Ganjalikhani-Hakemi M. Impact of IFN-β and LIF overexpression in human adipose-derived stem cells (hADSCs) properties. Journal of Cellular Physiology. Apr 2020, DOI: 10.1002/jcp.29717.
  32. Peyman A, Feizi A, Ganjalikhani-Hakemi M, Hosseini-Nasab F, Pourazizi M. Outcome of corneal collagen cross-linking in keratoconus: Introducing the predictive factors. Journal of Current Ophthalmology. 2020;32(1):19.
  33. Soltanpour Gharibdousti F, Fazeli Delshad B, Falak R, Shayanfar N, Ganjalikhani Hakemi M, Andalib A, et al. Induction of humoral immune responses and inhibition of metastasis in mice by a VEGF peptide-based vaccine. Iranian Journal of Basic Medical Sciences. 2020;23(4):507-14.
  34. Rahmati M, Ghannadian SM, Kasiri N, Ahmadi L, Motedayyen H, Shaygannejad V, …, Ganjalikhani-Hakemi M
    & Eskandari N. Modulation of Th17 Proliferation and IL-17A Gene Expression by Acetylated Form of Apigenin in Patients with Multiple Sclerosis. Immunological Investigations. Feb 2020; 26:1-14. DOI: 10.1080/08820139.2020.1726381
  35. Jafarinia M, Alsahebfosoul F, Salehi H, Eskandari N, Ganjalikhani-Hakemi M. Mesenchymal Stem Cell-Derived Exosomes: A novel cell-free therapy. Immunological Investigations. Feb 2020; 2:1-23. DOI: 10.1080/08820139.2020.1712416
  36. Peighambarzadeh F, Najafalizadeh A, Esmaeil N, Rezaei A, Ashrafi F, Ganjalikhani Hakemi M. Optimization of in vitro expansion and activation of human Natural killer cells against a breast cancer cell line. Avicenna Journal of Medical Biotechnology. Jan 2020; 12 (1): 17-23.
  37. Ghadiri N, Hosseini A, Ghaedi K, Emamnia NA, Ganjalikhani Hakemi M, Shirzad H, et al. Prediction of miR-34a and miR-215 impact on differentiation of naive CD4+ T cells to Th17 cells in multiple sclerosis. Journal of Shahrekord University of medical sciences. 2019;21(6):276-9.    
  38. Dehbashi M, Hojati Z, Motovali-bashi M, Ganjalikhani-Hakemi M, Shimosaka A. Integral membrane protein expression of human CD25 on the cell surface of HEK293 cell line: the available cellular model of CD25 positive to facilitate in vitro developing assays. Biomolecular Concepts. 2019; 10: 150-159.
  39. Andalib A, Rashed S, Dehbashi M, Hajati J, Noorbakhsh F, Ganjalikhani-Hakemi M. The Upregulation of hsa-mir-181b-1 and Downregulation of Its Target CYLD in the Late-Stage of Tumor Progression of Breast Cancer. Indian Journal of Clinical Biochemistry. March 2019:1-10; DOI: 10.1007/s12291-019-00826-z
  40. Hojati Z, Ganjalikhani-Hakemi M, Ameri M, Alimohammadi-Jelodar SF, Dehbashi M, Ganji MM, et al. Evaluation of Silencing Effect of miR-133a-5p Mimic on TIM-3 Expression in AML (HL-60) Cell Line. Indian Journal of Clinical Biochemistry. 2019:1-8; DOI: 10.1007/s12291-019-00834-z
  41. Fouladi S, Masjedi M, Ganjalikhani Hakemi M, Eskandari N. The Review of in Vitro and in Vivo Studies over the Glycyrrhizic Acid as Natural Remedy Option for Treatment of Allergic Asthma. Iranian Journal of Asthma Allergy and Immunology. February 2019;18(1):1-11.
  42. Shapoori S, Ganjalikhani-hakemi M, Rezaeepoor M, Alsahebfosoul F, Khosravi S, Etemadifar M, et al. Negative Regulation of Semaphorin 3A Expression in Peripheral Blood Mononuclear Cells Using MicroRNA-497-5p. Iranian Journal of Medical Sciences. July 2019;44 (4): 325-33. 
  43. Afshar-Ghasemlou S, Esmaeil N, Sherkat R, Yazdani R, Abbasi-Rad F, Ganjalikhani hakemi M et al. Increased IRF4 expression in isolated B cells from Common variable immunodeficiency (CVID) patients. Allergologia et Immunopathologia. 2019; 47(1):52-9.
  44. Alsahebfosoul F, Rahimpourkoldeh S, Eskandari N, Shaygannejad V, Ganjalikhani Hakemi M, Dabiri A, et al. Gene Expression of CD226 and Its Serum Levels in Patients With Multiple Sclerosis. Caspian Journal of Neurological Sciences. 2018; 4(3):91-7.
  45. Cheraghipour K, Shariati L, Khanahmad H, Ganjalikhani-hakemi M, Moridnia A, Mirian M et al. Induction of Apoptosis in Toxoplasma gondii Infected Hela Cells by Cisplatin and Sodium azide and Isolation of Apoptotic Bodiesand Potential Use for Vaccination against T. gondii. Iranian Journal of Parasitology 2018; 13(3): 406-415.
  46. Nekooie-Marnany N, Deswarte C, Ostadi V, Bagherpour B, Taleby E, Ganjalikhani Hakemi M et al. Impaired IL-12- and IL-23-Mediated Immunity Due to IL-12Rβ1 Deficiency in Iranian Patients with Mendelian Susceptibility to Mycobacterial Disease. Journal of Clinical Immunology. 2018; DOI: 10.1007/s10875-018-0548-1.
  47. Rezaei N, Talebi F, Ghorbani S, Rezaei A, Noorbakhsh F, Esmaeili A, Ganjalikhani-Hakemi M. MicroRNA-92a drives Th1 responses in the experimental autoimmune encephalomyelitis. Inflammation. 2018; doi: 10.1007/s10753-018-0887-3.
  48. Fouladi S, Masjedi M, Gangalikhani-Hakemi M, Eskandari N. Correlation of OX40 ligand on B cells with serum total IgE and IL-4 levels by CD4+ T cells in allergic rhinitis. Allergologia et Immunopathologia. 2018; doi: 10.1016/j.aller.2018.07.003.
  49. Moghaddam Y, Andalib A, Mohammad-Ganji M, Homayouni  V, Sharifi M, Gangalikhani-Hakemi M. Evaluation of the effect of TIM-3 suppression by miR-498 and its effect on apoptosis and proliferation rate of HL-60 cell line. Pathology-Research and Practice. Sep 2018; 214 (9): 1482-1488.
  50. Fouladi S, Masjedi M, Ghasemi R, Ganjalikhani-Hakemi M, Eskandari N. The in vitro impact of Glycyrrhizic acid on CD4+ T lymphocytes through OX40 receptor in the patients with allergic rhinitis. Inflammation. 12 Jul 2018. DOI: 10.1007/s10753-018-0813-8
  51. Meratian N, Esmaeil N, Rezaei A, Mehrabian F, Ganjalikhani-Hakemi M, Homayouni V. A simple and cost benefit method for monocyte isolation. Razi Journal of Medical Sciences. March 2018; 24 (165): 30-34.
  52. Yazdani R, Shapoori S, Rezaeepoor M, Sanaei R, Ganjalikhani-Hakemi M, Azizi G, et al. Features and Roles of T Helper 9 Cells and Interleukin 9 in Immunological Diseases.
    Allergologia et Immunopathologia. 2018; 47(1):90-104.
  53. Mohammad-Ganji M, Ganjalikhani-Hakemi M, Homayouni V, Rezaei A, Khanahmad H. Silencing of TIM-3 Expression by miR-326 Affects Apoptosis and Proliferation of Human HL-60 Leukemia Cell Line.
    International Journal of Hematology and Oncology 2018; 2 (28): doi:10.4999/uhod.182354.
  54. Ghadiri N, Emamnia N, Ganjalikhani-Hakemi M, Ghaedi K, Etemadifar M, Salehi M, et al. Analysis of the expression of mir-34a, mir-199a, mir-30c and mir-19a in peripheral blood CD4+T lymphocytes of relapsing-remitting multiple sclerosis patients.
    Gene 2018; 659: 109-117.
  55. Najafalizadeh A, Esmaeil N, Peighambarzadeh F, Mokarian F, Rezaei A,
    Ganjalikhani-Hakemi M    . Fully activated NK cells against HL-60 cells with simplified and efficient method for NK cells isolation and activation.
    Bionature 2018; 38(1): 12-23.
  56. Rezaeepoor M, Ganjalikhani-Hakemi M, Shapoori S, Eskandari N, Sharifi M, Etemadifar M, Mansourian M. Semaphorin-3A as an Immune Modulator is Suppressed by MicroRNA-145.
    Cell Journal 2018; 20(1):113-9.
  57. Yazdani R, Seify R, Ganjalikhani-Hakemi M, Abolhassani H, Eskandari N, Golsaz-Shirazi F, et al. Comparison of various classifications for patients with common variable immunodeficiency (CVID) using measurement of B-cell subsets. Allergologia et Immunopathologia. 2017; 45(2):183-92.
  58. Yazdani R, Ganjalikhani-Hakemi M, Esmaeili M, Abolhassani H, Vaeli S, Rezaei A, et al. Impaired Akt phosphorylation in B-cells of patients with common variable immunodeficiency. Clinical Immunology. 2017; 175:124-32.
  59. Talaei Z, Sheikhbahaei S, Ostadi V, Ganjalikhani Hakemi M, Meidani M, Naghshineh E, et al. Recurrent Vulvovaginal Candidiasis: Could It Be Related to Cell-Mediated Immunity Defect in Response to Candida Antigen. Int J Fertil Steril. 2017; 11(3):134-41.
  60. Afshar-Qasemloo S, Esmaeil N, Ganjalikhani-Hakemi M, Rezaei A, Yazdani R, Abbasi-Rad F. Comparison of B-Cells Differentiation to Plasmablasts at Presence of Anti-Human CD40 and Anti-Immunoglobulin M F(ab)'2 or Lipopolysaccharide and Anti-Human CD40 Stimulators (In-Vitro). Journal of Isfahan Medical School. 2017; 35(427):440-6.
  61. Sadri M, Ganjalikhani-Hakemi M, Akbari P, Salehi R, Rastaghi S, Ghasemi R, et al. Association between +4259 T>G and -574 G>T Polymorphisms of TIM-3 with Asthma in an Iranian Population. Iran J Allergy Asthma Immunol. 2017; 16(4):321-8.
  62. Rezaeepoor M, Shapoori S, Ganjalikhani-Hakemi M, Etemadifar M, Alsahebfosoul F, Eskandari N, et al. Decreased expression of Sema3A, an immune modulator, in blood sample of multiple sclerosis patients. Gene. 2017; 610:59-63.
  63. Rezaeepoor M, Shapoori S, Ganjalikhani-hakemi M, Etemadifar M, Alsahebfosoul F, Eskandari N, et al. Statistical support for Sema3A and multiple sclerosis. Gene. 2017; 626:87-8.
  64. Pouladian M, Ganjalikhani-Hakemi M, Alsahebfosul F, Homayouni V, Khosravi S, Etemadifar M, et al. The+ 4259A> C polymorphism of TIM-3 but not-1637C> T polymorphism of TIM-1 is associated with Multiple sclerosis in Isfahan population. Multiple sclerosis and related disorders. 2017; 18:152-6.
  65. Mahmoudi MB, Abed Khojasteh M, Alsahebfosoul F, Gharibdoost F, Mostafaei S,
    Ganjalikhani    ‐hakemi M, et al. Expressions of p53 and PUMA in fibroblasts of systemic sclerosis patients are normal at transcription level. Journal of cosmetic dermatology. 2017: doi: 10.1111/jocd.12420.
  66. Khazraei-Moradian S, Ganjalikhani-Hakemi M, Andalib A, Yazdani R, Arasteh J, Kardar GA. The Effect of Licorice Protein Fractions on Proliferation and Apoptosis of Gastrointestinal Cancer Cell Lines. Nutr Cancer. 2017; 69(2):330-9.
  67. Jafarinia M, Lotfi N, Ganjalikhani-hakmi M, Rezaei A. Regulatory T Cells in Colorectal Cancer. Immuno regulation. 2017; 1(1):1-6.
  68. Homayouni V, Khanahmad H, Ganjalikhani-Hakemi M, Behdani M, Ghasemi P, Rezaei A. Stimulation of Camel Polyclonal Antibody against Human T cell Immunoglobulin and Mucin 3. Iranian Journal of Biotechnology. 2017; 15(3):166-71.
  69. Ganjalikhani-Hakemi M, Yazdani R, Esmaeili M, Abolhassani H, Rae W, Azizi G, et al. Role of Apoptosis in the Pathogenesis of Common Variable Immunodeficiency (CVID). Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders). 2017; 17(4):332-40.
  70. Feizollahzadeh S, Kouhpayeh S, Rahimmansh I, Khanahmad H, Sabzehei F,
    Ganjalikhani-hakemi M    , et al. The Increase in Protein and Plasmid Yields of E. coli with Optimized Concentration of Ampicillin as Selection Marker. Iranian Journal of Biotechnology. 2017; 15(2):128-34.
  71. Emamdoost F, Khanahmad H, Ganjalikhani-hakemi M, Doosti A. The miR-125a-3p inhibits TIM-3 expression in AML cell line HL-60 in vitro. Indian Journal of Hematology and Blood Transfusion. 2017; 33(3):342-7.
  72. Ansari M, Yazdani R, Sherkat R, Homayouni V, Ganjalikhani-Hakemi M, Rezaei A. Decreased Expression of B cell Maturation Antigen in Patients with Common Variable Immunodeficiency. Pediatric Allergy, Immunology, and Pulmonology. 2017; 30(1):7-13.
  73. Abbasirad F, Ganjalikhani-Hakemi M, Esmaeil N, Farrokhi S, Sherkat R, Yazdani R, et al. Assessment of the Expression Level of B-Cell Lymphoma 6 (BCL6) in Peripheral Blood CD38+ B Lymphocytes in Patients with Common Variable Immunodeficiency (CVID). Journal of Isfahan Medical School. 2017; 35(432):629-34.
  74. Yazdani R, Fatholahi M, Ganjalikhani-Hakemi M, Abolhassani H, Azizi G, Hamid KM, et al. Role of apoptosis in common variable immunodeficiency and selective immunoglobulin A deficiency. Molecular immunology. 2016; 71:1-9.
  75. Soltanpour-Gharibdousti FK, Gholam Ali, Fazeli-Delshad B, Falak R, Ganjalikhani-Hakemi M, Andalib A. Bioinformatic Designing for Producing Vaccine Peptide of Human Vascular Endothelial Growth Factor (VEGF-A), and Evaluation of Polyclonal Antibodies in Mice. Journal of Isfahan Medical School. 2016; 34(398):1054-9.
  76. Mazrouei F, Ganjalikhani‐Hakemi M, Salehi R, Alesahebfosoul F, Etemadifar M, Pouladian M, et al. Association of TIM‐1 5383‐5397ins/del and TIM‐3‐1541C> T polymorphisms with multiple sclerosis in Isfahan population. International journal of immunogenetics. 2016; 43(3):131-4.
  77. Kavoosi F, Nikbakht-Dastjerdi M, Valiani A, Esfandiari E, Sanaei M, Ganjalikhani-Hakemi M. Genistein potentiates the effect of 17-beta estradiol on human hepatocellular carcinoma cell line. Advanced biomedical research. 2016; 5: doi: 10.4103/2277-9175.187395.
  78. Hosseini A, Ghaedi K, Tanhaei S, Ganjalikhani-Hakemi M, Teimuri S, Etemadifar M, et al. Upregulation of CD4+ T-Cell Derived MiR-223 in The Relapsing Phase of Multiple Sclerosis Patients. Cell Journal (Yakhteh). 2016; 18(3):371-80.
  79. Homayouni  V, Ganjalikhani-hakemi M, Rezaei A, Khanahmad H, Behdani M, Kazemi Lomedasht F. Preparation and characterization of a novel nanobody against T-cell immunoglobulin and mucin-3 (TIM-3). Iranian Journal of Basic Medical Sciences. 2016; 19:1201-8.
  80. hassanzadeh MA, Eskandari N, Ganjalikhani-Hakemi M, Sherkat R. Investigating the Frequency of the Peripheral Blood B and Transitional B Cells in the Patients with Common Variable Immunodeficiency. Journal of Isfahan Medical School. 2016; 33(357):1851-6.
  81. Fooladinezhad H, Khanahmad H, Ganjalikhani-Hakemi M, Doosti A. Negative regulation of TIM-3 expression in AML cell line (HL-60) using miR-330-5p. British journal of biomedical science. 2016; 73(3):129-33.
  82. Feizollahzadeh S, Khanahmad H, Rahimmanesh I, Ganjalikhani-hakemi M, Andalib A, Sanei MH, et al. Expression of biologically active murine interleukin-18 in Lactococcus lactis. FEMS microbiology letters. 2016; 363(21):pii: fnw234.
  83. Fazeli-Delshad B, Ganjalikhani-Hakemi M, Soltanpour-Gharibdousti F, Shayanfar N, Falak R, Kardar GA. Evaluation of the Functionality of 4T1 Cell Line in Development of Metastatic Cancer in Balb/c Mice as an Animal Model. Journal of Isfahan Medical School. 2016; 34(396):985-90.
  84. Eskandari N, hassanzadeh MA, Ganjalikhani-Hakemi M, Sherkat R, Khanahmad H, Yazdani Y. Evaluation of BAFF-R Mutations in Iranian Patients with Common Variable Immune Deficiency (CVID). ARC Journals of Immunology and Vaccines. 2016; 1(1):1-8.
  85. Ansari M, Ganjalikhani-Hakemi M, Sherkat R, Rezaei A, Yazdani R, Khosravi S. Evaluation of Mutation in B cell Maturation Antigen (BCMA) Gene in Patients with Common Variable Immunodeficiency (CVID). Journal of Isfahan Medical School. 2016; 34(383):555-62.
  86. Abed Khojasteh M, Alsahebfosoul F, Mahmoudi M, Mahmoudi MB, Mostafaei S,
    Ganjalikhani-hakemi M    , et al. Comparison of the expression levels of Fas and Apaf-1 genes in systemic sclerosis dermal fibroblasts. Tehran University Medical Journal TUMS Publications. 2016; 74(4):282-8.
  87. Yazdani R, Sharifi M, Shirvan AS, Azizi G, Ganjalikhani-Hakemi M. Characteristics of innate lymphoid cells (ILCs) and their role in immunological disorders (an update). Cell Immunol. 2015; 298(1-2):66-76.
  88. Shirzade H, Meshkat R, Ganjalikhani‐Hakemi M, Mosayebian A, Ghasemi R, Deress F, et al. Association analysis of− 416 G> C polymorphism of T‐cell immunoglobulin and mucin domain‐1 gene with asthma in Iran. International journal of immunogenetics. 2015; 42(4):265-9.
  89. Sherkat R, Ali-Hassanzadeh M, Eskandari N, Ganjalikhani-Hakemi M, Esmaeil N, Rezaei N. Clinical Features of Immunological Dysregulation in Common Variable Immunodeficiency in Iran. British Journal of Medicine and Medical Research. 2015; 7(8):647-53.
  90. Shajanian S, Gharagozloo M, Ganjalikhani-Hakemi M, Rafiee M. Comparing In-Vitro Effects of Two Immunosuppressive Drugs on the Expression of Foxp3 from Naïve CD4+ T Cells. Journal of Isfahan Medical School. 2015; 33(329):457-66.
  91. Sadri  M, Ganjalikhani-Hakemi M, Salehi R, Ghasemi R, Rastaghi S. Prevalence of TIM-3 Gene Polymorphisms in Patients with Asthma and its correlation with Serum Levels of Immunoglobulin-E of These Patients in Isfahan, Iran. Journal of Isfahan Medical School. 2015; 32(314):2193-201.
  92. Pouladian M, Ganjalikhani-Hakemi M, Salehi R, AlSahebfosul F, Khosravi S, Etemadifar M, Mazrouei F. Comparing the frequency of TIM-3 polymorphism in Multiple Sclerosis patients with healthy controls. Journal of Isfahan Medical School. 2015; 33(341):1066-75.
  93. Naghavian R, Honardoost M, Hosseini A, Ghaedi K, Etemadifar M, Nasr Esfahani M,
    Ganjalikhani-Hakemi M. The possibility of miR-20a/b & miR-93 role in differentiation of naïve CD4+ to Th17 cells in multiple sclerosis. Scientific Journal of Iranian Blood Transfusion Organization. 2015; 12(1):39-45.
  94. Naghavian R, Ghaedi K, Kiani-Esfahani A, Ganjalikhani-Hakemi M, Etemadifar M, Nasr-Esfahani MH. miR-141 and miR-200a, Revelation of New Possible Players in Modulation of Th17/Treg Differentiation and Pathogenesis of Multiple Sclerosis. PLoS One. 2015; 10(5):e0124555.
  95. Mollainezhad H, Eskandari N, Pourazar A, Andalib A, Salehi M, Ganjalikhani-Hakemi M. miR-370 Expression Analysis in Breast Cancer. Journal of Isfahan Medical School. 2015; 33(339):924-31.
  96. Mazrouei F, Ganjalikhani-Hakemi M, Salehi R, Ale-Sahebfosoul F, Etemadifar M, Zarkesh-Esfahani H. The Frequency of TIM-3-1541C>T Polymorphisms and its Association with Multiple Sclerosis. Journal of Isfahan Medical School. 2015; 33(335):739-46.
  97. Haghighatfard H, Samaei N, Farazmandfar T, Ganjalikhani-Hakemi M, Yamchi A, Jadidi-Niaragh F, et al. Molecular Cloning and Expression of Novel Fibroblast Growth Factor-2 Conjugated with Immunodominant Domains of Pseudomonas exotoxin. Biomedical and Pharmacology Journal. 2015; 8(2):1195-200.
  98. Ghatrehsamani M, Soleimani M, Moayedi-Esfahani BA, Ganjalikhani-Hakemi M, Shirzad H, Eskandari N, et al. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin decrease expression of aryl hydrocarbon receptor in peripheral lymphocyte of β-thalassemia major patients. Advanced biomedical research. 2015; 4: doi: 10.4103/2277-9175.166.
  99. Ghatrehsamani M, Soleimani M, Moayedi-Esfahani BA, Shirzad H, Ganjalikhani-Hakemi M, Mossahebimohammadi M, et al. Tumor necrosis factor-α inhibits effects of aryl hydrocarbon receptor ligands on cell death in human lymphocytes. Advanced biomedical research. 2015; 4: doi: 10.4103/2277-9175.166163.
  100. Ebrahimi M, Kazemi T, Ganjalikhani-Hakemi M, Majidi J, Khanahmad H, Rahimmanesh I, et al. Development of a Stable Cell Line, Overexpressing Human T-cell Immunoglobulin Mucin 1. Iran J Biotechnol. 2015; 13(4):25-31.
  101. Nikbakht-Dastjerdi M, Kavoosi F, Valiani A, Esfandiari E, Sanaei M, Sobhanian S,
    Ganjalikhani-Hakemi M, et al. Inhibitory Effect of Genistein on PLC/PRF5 Hepatocellular Carcinoma Cell Line. Int J Prev Med. 2015; 6(1):54-61.
  102. Mosayebian A, Ganjalikhani Hakemi M, Meshkat R, Ghasemi R, Khanahmad H, Samadi M. Association between Interleukin-23 Receptor R381Q Gene Polymorphism and Asthma. Iran J Allergy Asthma Immunol. 2015; 14(4):386-91.
  103. Yazdani R, Ganjalikhani-Hakemi M, Sherkat R, Homayouni V, Farahani R. Genetic defects and the role of helper T-cells in the pathogenesis of common variable immunodeficiency. Advanced biomedical research. 2014; 3(2): doi: 10.4103/2277-9175.124627.
  104. Shirzad H, Meshkat R, Gangalikhani-Hakemi M, Salehi R, Ghasemi R, Hashemzadeh M, et al. Association Analysis of T-Cell Immunoglobulin and Mucin 1 Gene 5383-5397 Insertion/Deletion Polymorphism with Asthma and Total Serum Immunoglobulin E Levels in Patients with Asthma and Controls. Journal of Isfahan Medical School. 2014; 32(300):1423-32.
  105. Sherkat R, Yazdani R, Ganjalikhani-Hakemi M, Homayouni V, Farahani R, Hosseini M, et al. Innate lymphoid cells and cytokines of the novel subtypes of helper T cells in asthma. Asia Pacific allergy. 2014; 4(4):212.
  106. Yazdani  R, Ganjalikhani-Hakemi M, Sherkat R, Rezaei A, Farahani R, Beiranvand B. Evaluation of IL-17 gene expression in peripheral blood and sputum of asthma patients and healthy individuals. Tehran University Medical Journal TUMS Publications. 2014; 72(9):595-600.
  107. Moballegh-Naseri M, Khanahmad H, Homayouni V, Ganjalikahni-Hakemi M, Salehi M, Rahim-Manesh I, et al. Producing Recombinant HEK293 T-cells with High Expression of T-cell Immunoglobulin and Mucin Domain-3 (Tim3) Protein. Journal of Isfahan Medical School. 2014; 32(317):2312-23.
  108. Komijany F, Dashti GR, Salamat MR, Ganjalikhani-Hakemi M, Abdar-Esfahani M, Adibi A. the Relationship of the Serum Level of Osteoprotegerin and Bone Mineral Density in Postmenopausal Women. Journal of Isfahan Medical School. 2014; 32(318):2349-59.
  109. Khazraei-Moradian S, Andalib A, Ganjalikhani-Hakemi M, Safari Z, Zare A, Kardar GA. The Effect of Protein Extract of Licorice Root in Proliferation of HT-29 and CT26 Cancer Cell Lines. Journal of Isfahan Medical School. 2014; 32(298):1338-46.
  110. Ganjalikhani-Hakemi M, Yazdani R, Sherkat R, Homayouni V, Masjedi M, Hosseini M. Evaluation of the T helper 17 cell specific genes and the innate lymphoid cells counts in the peripheral blood of patients with the common variable immunodeficiency. Journal of research in medical sciences. 2014; 19(Suppl 1):S30.
  111. Ganjalikhani Hakemi M, Ghaedi K, Homayouni V, Andalib A, Hosseini M, Rezaei A. Positive and negative regulation of Th17 cell differentiation: evaluating the impact of RORC2. Cell Journal 2014; 16(3):343-52.
  112. Farahani R, Sherkat R, Ganjalikhani-Hakemi M, Eskandari N, Yazdani R. Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma. Advanced biomedical research. 2014; 3(127): doi: 10.4103/2277-9175.133249.
  113. Alani B, Salehi R, Sadeghi P, Zare M, Khodagholi F, Arefian E, Ganjalikhani-Hakemi, M, et al. Silencing of Hsp90 chaperone expression protects against 6-hydroxydopamine toxicity in PC12 cells. Journal of Molecular Neuroscience. 2014; 52(3):392-402.
  114. Yazdani R, Ganjalikhani-Hakemi M, Sherkat R, Masjedi M, Zarkesh H, Hosseini M. Evaluation of IL-17 Gene Expression in the Peripheral Blood of Patients with Common Variable Immunodeficiency. Journal of Isfahan Medical School. 2013; 31(230):358-63.
  115. Ganjalikhani hakemi M, Hashemi M. siRNA delivery improvement co-formulation of different modified polymers in erythroleukemic cell line K562 Iranian Journal of Basic Medical Sciences. 2013; 16: 973-8.
  116. Ganjalikhani Hakemi M, Ghaedi K, Andalib A, Homayouni V, Hosseini M, Rezaei A. RORC2 gene silencing in human Th17 cells by siRNA: design and evaluation of highly efficient siRNA. Avicenna journal of medical biotechnology. 2013; 5(1):10.
  117. Behfarnia P, Birang R, Pishva SS, Ghanjalikhani Hakemi M, Mitra MK. Expression Levels of Th-2 and Th-17 Characteristic Genes in Healthy Tissue versus Periodontitis. Journal of Dentistry of Tehran University of Medical Sciences. 2013; 10 (1):23-31.
  118. Adibrad M, Deyhimi P, Ganjalikhani Hakemi M, Behfarnia P, Shahabuei M, Rafiee L. Signs of the presence of Th17 cells in chronic periodontal disease. Journal of periodontal research. 2012; 47(4):525-31.
  119. Ganjalikhani Hakemi M, Ghaedi K, Andalib A, Hosseini M, Rezaei A. Optimization of human Th17 cell differentiation in vitro: evaluating different polarizing factors. In Vitro Cellular & Developmental Biology-Animal. 2011; 47(8):581.
  120. Nicknam MH, Mahmoudi M, Amirzargar AA, Ganjalikhani-Hakemi M, Khosravi F, Jamshidi AR, et al. Determination of HLA-B27 subtypes in Iranian patients with ankylosing spondylitis. Iranian Journal of Allergy, Asthma and Immunology. 2008; 7(1):19-24.
  121. Nicknam M, Ganjalikhani hakemi M, Jamshidi A, Khosravi F, Amirkhani A, Narouinejad M, et al. Association between HLA-B27 antigen and ankylosing spondylitis in iranian patients. Hakim. 2005; 8(1):29-34.
  122. Nicknam M, Jamshidi A, Ganjalikhani Hakemi M, Khosravi F, Amirkhani A, Narouinejad M, et al. Comparison of validity of microlymphocytotoxicity and flowcytometry methods with PCR for HLA-B27 antigen typing. Medical Journal of the Islamic Republic of Iran (MJIRI). 2003; 17(1):75-9.





PATENTS



  1. Wound tighten band aids. Patent Number: 96962/Oct 2018 as A61L;A61F international level by Iran Patent Office.
  2. Recombinant IFNβ-ScFv fusion protein against collagen II. Acceptance Number: 139850840003000806 by Iran Patent Office.
  3. Wound healing and bleeding stop ointment. Registered for evaluation as 139632157143000223 by Iran Patent Office.

GENES REGISTERED



  1. Populus nigra profilin. Gene Bank: MN832852. 326 bp, linear mRNA, PLN: 29 Feb 2020.




PRESENTATIONS/ABSTRACTS



  1. Silencing of Tim-3 expression by miR-326 affects apoptosis and proliferation of human HL-60 leukemia cell line. May 2018, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2018.
  2. Preparation and characterization of a novel nanobody against T-cell immunoglobulin and mucin-3 (TIM-3). May 2018, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2018.
  3. Negative regulation of Semaphorin 3A expression in peripheral blood ononuclear cells using microRNA-497-5p. May 2018, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2018.
  4. Evaluation of the effect of TIM-3 suppression by miR-498 and its effect on apoptosis and proliferation rate of HL-60 cell line. May 2018, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2018.
  5. Down regulation of neuroimmune Semaphorin 3A in peripheral blood mononuclear cells and its serum level of patients with multiple sclerosis. May 2018, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2018.
  6. Molecular docking and molecular dynamic analysis of anti-CD25 chimeric antigen receptor, (Poste) Nov 2016, Beijing, China. Published in 7th ACTO meeting abstract book, Nov 2016.
  7. Designing of peptide ELISA kit for Evaluation of anti VEGF IgGin mice model 
    serum,(Poster) May 2016, Tabriz, Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2016.
  8. Presentation of infections and immune dysregulations in CVID patients and its relation to their clinical and immunological characteristics in Isfahan. ECID, Prague, Czech. (Oral) Oct 2014. J Clin Immunol (2014) 34 (Suppl 2):S421.
  9. Dendritic cell-based Immunotherapy. Vaccines and their applications. Re-instruction program, (presentation) Oct 2014. Al-Zahra haspital, Isfahan, Iran.
  10. Comparison of the frequency of R381Q functional variant of IL-23 receptor gene, in asthmatic patients and control group. 12th International Congress of Immunology & Allergy, (Oral) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  11. Evaluation of newly identified helper T cells specific cytokines expressions in the peripheral blood and sputum samples of patients with Asthma. 12th International Congress of Immunology & Allergy, (Oral) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  12. The +4259 G>T of TIM-3 polymorphism is associated with asthma susceptibility in the Isfahan population. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  13. Polymorphism-574 G>Tin TIM-3 is not associated with asthma in the Isfahan population. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  14. Effect of Licorice protein fractions on growth of gastrointestinal cancer cell lines. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  15. A comparison of the effects of silymarin and rapamycin on the generation of regulatory T cells from naïve CD4+ T cells in vitro. 12th International Congress of Immunology & Allergy, (Oral) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  16. Association analysis of TIM-3 -1541C>T polymorphism with multiple sclerosis in Isfahan population. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  17. Association analysis of TIM1 -416G>C polymorphism with asthma in Chaharmahal va Bakhtiari, Iran. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  18. Association analysis of TIM-1 5383_5397 insertion/deletion polymorphism with asthma and total serum Immunoglobulin E levels Chaharmahal va Bakhtiari, Iran. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  19. Establishment of a recombinant HEK cell line over expressing TIM-3 protein. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.
  20. Evaluation of VEGF peptide based vaccine on inhibition of proliferation in tumor cell lines. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  21. The role of Mir-199a in Multiple Sclerosis according to Bioinformatical prediction. 12th International Congress of Immunology & Allergy, (Poster) May 2014, Tehran Iran.Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2014.
  22. Optimization of human Th17 cell differentiation
    in vitro: evaluating different polarizing factors.5th Congress of Laboratory&clinic, (poster) Jan 2013, Tehran Iran.
  23. Comparison of expression of Th17 cell's characteristic genes and ILC count in CVID patients with normal controls. 2ndInternational Congress of Immunology, Asthma& Allergy, (Oral) Feb 2013, Tehran Iran.
  24. Signs of the presence of Th17 cells in chronic periodontal disease. 11th International Congress of Immunology & Allergy, (Oral) May 2012, Tehran Iran.
  25. Designing and evaluating highly efficient siRNAs for silencing RORC2 in human Th17 cells. 11th International Congress of Immunology & Allergy, (Oral) May 2012, Tehran Iran.
  26. Designing and evaluating highly efficient siRNAs for silencing RORC2 in human Th17 cells. 4th Congress of Laboratory&clinic, (poster) Dec 2011, Tehran Iran.
  27. Efficient generation of human Th17 cells from naïve helper T cells. 10th International Congress of Immunology & Allergy, (Poster) May 2010, Tehran Iran.
  28. Frequency of HLA-B27 subtypes in Iranian patients with Ankylosing Spondylitis using of PCR-SSP method.1st Iranian Congress of Laboratory and Internal Medicine, (Poster) Dec 11-14,2007, Tehran, Iran. Published in Abstract Book of Laboratory and Internal Medicine, Winter 2007, p81.
  29. Evaluation of electrophoretic changes in serum proteins and presence of paraproteins in serum samples of 257 Iranian normal individuals aged over 70. 12th International Congress of Immunology & the 4th Annual Meeting of FOCIS, (poster)July 18-23, 2004, Montreal, Canada. Published as a supplement in Clinical Investigative Medicine.
  30. Evaluation of electrophoretic changes in serum proteins and presence of paraproteins in serum samples of 257 Iranian normal individuals aged over 70. 7th Iranian Congress of Immunology and Allergy, (Oral presentation) May 2004, Mashad, Iran. Published in Iranian Journal of Immunology, Supplement, Spring 2004, p282.
  31. Comparison of validity of microlymphocytotoxicity and flow cytometry methods with PCR for HLA-B27 antigen typing. 6th Iranian Congress of Immunology and Allergy, (Oral presentation) May 2002, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2002, p56.
  32. Association between Ankylosing spondylitis and HLA-B27 antigen in Iran. 6th Iranian Congress of Immunology and Allergy, (poster) May 2002, Tehran, Iran. Published in Iranian Journal of Allergy, Asthma & Immunology, Supplement, May 2002, p24.
  33. Comparison of validity of microlymphocytotoxicity and flow cytometry methods with PCR for HLA-B27 antigen typing. 13th International Congress of Histocompatibility & Immungenetics, Seattle Convention Center, Seattle, Washington, U.S.A, (Oral presentation) May 18-22, 2002. Published in Tissue Antigen, volume 59, supplement 2002, p89.
  34. Association between Ankylosing spondylitis and HLA-B27 antigen in Iran. 13th International Congress of Histocompatibility & Immungenetics, SeattleConvention Center, Seattle, Washington, U.S.A, (poster) May 18-22, 2002. Published in Tissue Antigen, volume 59, supplement 2002, p73.



EDUCATION/TEACHING



  1. Tuition of Immunology for students preparing for M.Sc entrance exam. Sina Teb Institute. 2002-2003.
  2. Tuition of Immunology for students preparing for M.Sc entrance exam. Mahan Institute. 2002-2004.
  3. Tuition of Immunology for students preparing for M.Sc entrance exam. Rahian-e Arshad Institute. 2002-2003
  4. Tuition of Immunology for students preparing for M.Sc entrance exam. Jahad-e Daneshgahi (Isfahan University). 2006-2012.
  5. Tuition of students of medicine. IsfahanUniversity of Medical Sciences. Since 2008.
  6. Tuition of Immunology for B.Sc students of Niutrition, Nursing and Operation room. IsfahanUniversity of Medical Sciences. Since 2008.
  7. Tuition of Immunology for B.Sc students of Laboratory Sciences. IsfahanUniversity of Medical Sciences. Since 2012.
  8. Tuition of Immunology for students of Pharmacy. IsfahanUniversity of Medical Sciences. Since 2012.
  9. Tuition of Immunology 1 for M.Sc students of Immunology. IsfahanUniversity of Medical Sciences. Since 2012.
  10. Tuition of Immunology 2 for M.Sc students of Immunology. IsfahanUniversity of Medical Sciences. Since 2012.
  11. Tuition of immunochemistry for MSc students in Immunology. IsfahanUniversity of Medical Sciences. Since 2013.
  12. Tuition of Experimental methods in immunology for MSc students in Immunology. IsfahanUniversity of Medical Sciences. Since 2013.
  13. Tuition of elementary Bioinformatic in molecular biology for M.Sc and PhD students in Immunology. Isfahan University of Medical Sciences. Since 2008.
  14. Tuition of selective courses in immunology for Ph.D students in Immunology. IsfahanUniversity of Medical Sciences. Since 2011.
  15. Tuition of advanced immunology and Immunological methods for Ph.D students in Microbiology. IsfahanUniversity of Medical Sciences. Since 2012.
  16. Tuition of immunochemistry for Ph.D students in Immunology. IsfahanUniversity of Medical Sciences. Since 2013.
  17. Tuition of immunochemistry for Ph.D students in Biochemistry. IsfahanUniversity of Medical Sciences. Since 2013.
  18. Tuition of immunopathology for Ph.D students in Immunology. IsfahanUniversity of Medical Sciences. Since 2013.
  19. Tuition of clinical immunology for Ph.D students in Molecular medicine. IsfahanUniversity of Medical Sciences. Since 2013.



TECHNICAL SKILLS



  1. Routine laboratory skilles (Hematology, Serology, Biochemistry, Microbiology,Parasitology& etc).
  2. Electrophoresis (Cellulose Acetate, Agarose, IEF, PAGE& SDS- PAGE)
  3. ELISA& RIA
  4. Microlymphocytotoxicity for HLA class I typing.
  5. Flow cytometery
  6. PCR, RT-PCR& Real Time PCR
  7. Cell separation, culture and differentiation
  8. Cell transfection and Gene silencing
  9. In silico designing of siRNA
  10. Immunoblotting (Western & Dot Blot)
  11. HPLC
  12. GMP certificate
  13. Teaching methods certificate.



WORKSHOPS HELD:



  1. SDS-PAGE & Western Blotting. Isfahan University of Medical Sciences, Isfahan, Iran (Oct 2014).
  2. An introduction to bioinformatics. Isfahan University of Medical Sciences, Isfahan, Iran (Jun 2014).
  3. Gene silencing and designing siRNA. 12th International congress of immunology, Tehran, Iran (May 2014).
  4. Gene silencing and designing siRNA. Isfahan University of Medical Sciences, Isfahan, Iran (Apr 2014).
  5. Flowcytometry. Isfahan University of Medical Sciences, Isfahan, Iran (Oct 2013).
  6. Bioinformatics and designing primer fo

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