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Navid Abedpoor




























 EDUCATION AND TRAINING
  
Department of Physical Education and Sports Science, College of Physical Education & Sport Sciences, (Isfahan) Khorasgan Branch, Islamic Azad University


MSc, Sport & Nutrition

  		                                         Isfahan, Iran

                                         2014-2016
  Department of Agriculture, University Islamic Azad           


  BSc, Food Sciences & Engineer 		                                          Isfahan, Iran

                                         2008-2012
  WORK
EXPERIENCE:

  Researcher in Royan institute in Cellular Biotechnology lab                                                  2012-2019
  

    Researcher in University of Isfahan                                                                                       2019-2021


    Researcher in Azad Islamic University of Isfahan                                                                 2021-Present



PUBLICATIONS



  1. Journal Articles

1. Navid Abedpoor, Farzaneh Taghian, Kamran Ghaedi, Iman Niktab, Zahra Safaeinejad,  Farzaneh Rabiee, Sommayeh Tanhaei, Mohammad Hossein Nasr Esfahani. (2018) PPARγ/Pgc-1α-Fndc5 pathway up-regulation in gastrocnemius and heart muscle of exercised, branched chain amino acid diet fed mice. Nutrition & Metabolism. IF: 4.5

2. Mehrnosh Bahadorani, Marzie Tavalaee, Navid Abedpoor, Kamran Ghaedi, Mohamad Naser Nazem, Mohammad Hossein Nasr-Esfahani, (2018). Effects of branched-chain amino acid supplementation during aerobic training on sperm parameters and chromatin integrity in male mouse. Andrologia. IF: 2.7

3. Fatemeh Azizian-Farsani, Navid Abedpoor, Mohammad Hasan Sheikhha, Ali Osmay Gure, Mohammad Hossein Nasr Esfahani, Kamran Ghaedi. (2020). Receptor for advanced glycation end products acts as a fuel to colorectal cancer development. Frontiers in Oncology. IF: 6.5

4. Fatemeh Azizian-Farsani, Marcin Osuchowski, Navid Abedpoor, Farzad Seyed Forootan, Maryam Derakhshan, Mohammad Hossein Nasr-Esfahani, Mohammad Hasan Sheikhha, Kamran Ghaedi. (2020). Anti-inflammatory and -apoptotic effects of an herbal extract on DSS-induced colitis in mice fed with high AGEs-fat diet. Scientific Reports. Nutrition & Metabolism. IF: 4.5   

5. Golbarg Rahimi; Salime Heydari; Bahare Rahimi; Navid Abedpoor; Iman Nicktab; Zahra Safaeinejad; Maryam Peymani; Farzad Seyed Forootan; Zahra Derakhshan; Mohammad Hossein Nasr Esfahani, Kamran Ghaedi. (2020). A combination of herbal compound (SPTC) along with exercise or metformin more efficiently alleviated diabetic complications through down-regulation of stress oxidative pathway upon activating Nrf2-Keap1 axis in AGEs rich diet-induced type 2 diabetic mice.  Nutrition and metabolism.IF:4.5

6. Fahimeh Akbarian, Mohsen Rahmani, Marziyeh Tavalaee, Navid Abedpoor, Mozhdeh Taki, Kamran Ghaedi, Mohammad Hossein Nasr-Esfahani. (2021). Effect of different high-fat and AGEs diets in obesity and diabetes-prone C57BL/6 mice on sperm function. International Journal of Fertility and Sterility. IF:2.7

7. Navid Abedpoor, Farzaneh Taghian, Fatemeh Hajibabaie. (2022). Physical activity ameliorates the function of organs via adipose tissue in metabolic diseases. Acta histochemical. IF: 2.7

8. Fatemeh Hajibabaie, Navid Abedpoor, Nazanin Asareh, Mohammad Amin Tabatabaiefar, Ali Zarrabi and Laleh Shariati. (2022). A cocktail of microRNAs as an advance diagnostic signature in stomach-colorectal cancers hallmarks incidence: a systematic review. Personal Medicine.

9. Navid Abedpoor, Farzaneh Taghian, Fatemeh Hajibabaie. (2022). Cross Brain-Gut Analysis Highlighted Hub Genes and LncRNAs Networks Differentially Modified During Leucine Consumption and Endurance Exercise in Mice with Depression Like Behaviors. Molecular Neurobiology. IF: 5.5

10. Navid Abedpoor, Iman Niktab, Mohammad-Hossein Beigi, Masoud Baghi, Fahimeh Arzande, Naeimeh Rezaei, Mohammad-Sajad Zare, Timothy L. Megraw, Hoi-Ying Holman, Amirkianoosh Kiani, Farzad Seyed Forootan, Hossein Baharvand, Mohammad Hossein Nasr Esfahani, Kamran Ghaedi (2022). Exercise facilitates the browning of fat tissue by up-regulating Irisin receptors. (Submitted).

11. Maryam Haghparast Azad, Iman Niktab, Shaghayegh Dastjerdi, Navid Abedpoor, Golbarg Rahimi, Zahra Safaeinejad, Maryam Peymani, Farzad Seyed Forootan, Majid Asadi-Shekaari, Mohammad Hossein Nasr Esfahani & Kamran Ghaedi. The combination of endurance exercise and SGTC (Salvia–Ginseng–Trigonella–Cinnamon) ameliorate mitochondrial markers’ overexpression with sufficient ATP production in the skeletal muscle of mice fed AGEs-rich high-fat diet. (2022). Nutrition & Metabolism.

12. Golnaz Pakravan, Maryam Peymani, Navid Abedpoor, Zahra Safaeinejad, Mehrdad Yadegari, Maryam Derakhshan, Mohammad Hossein Nasr Esfahani, Kamran Ghaedi. Antiapoptotic and anti-inflammatory effects of Pparγ agonist, pioglitazone, reversed Dox-induced cardiotoxicity through mediating of miR-130a downregulation in C57BL/6 mice. (2022). Journal of Biochemical and Molecular Toxicology.

13. Fatemeh Azizian-Farsani, Navid Abedpoor, Maryam Derakhshan, Mohammad Hossein Nasr-Esfahani, Mohammad Hasan Sheikhha, Kamran Ghaedi. Protective Effects of the Combination of the Herbal Compound Against Inflammation Related to Obesity and Colitis Induced by Diet in Mice. (2022). Iranian Journal of Diabetes and Obesity. 

14. Global multi-stakeholder endorsement of the MAFLD definition. (2022). The Lancet Gastroenterology & Hepatology. IF: 200

  1. Book Chapter:

Navid Abedpoor, Kamran Ghaedi.
Branched-Chain Amino Acids and Their Role in Disease. Nova Science Publishers, Inc. 2020


PEER-REVIEW ANDOTHERACADEMICSERVICE










ACS Chemical Neuroscience, ACTA Scientific Nutrition, Frontiers Molecular Biosciences, Gene Journal, Journal of Natural Science, Biology and Medicine, Acta Histochemica, Journal of Natural Science, Biology and Medicine, Gene Report, Diabetes therapy, DOVEpress, Endocrinologia Diabetes y Nutricion, Diabetes Obesity and metabolism (DOM)
 Referee


INVITEDTALKS



  1. Navid Abedpoor, Kamran Ghaedi, Mohammad Hossein Nasr Esfahani. 1. PPARγ/Pgc-1α-Fndc5 pathway up-regulation in Gastrocnemius and Heart muscle of exercised, branched chain amino acid diet fed mice. 17th International Conference on Nutrition and Fitness. Held during May 23-24, 2019.
    Vienna, Austria.
  2.  Navid Abedpoor, Kamran Ghaedi, Mohammad Hossein Nasr Esfahani.
    Induced Type 2 Diabetes by High fat in male C57BL/6. Type 2 diabetes and Obesity symposium. 2020. Isfahan
  3. Navid Abedpoor, Kamran Ghaedi, Mohammad Hossein Nasr Esfahani. 2020.
    Type 2 diabetes and metabolism pathway. Yazd
  4. Navid Abedpoor, Farzaneh Taghian, Fatemeh Hajibabaie. Physical activity modulated molecular signaling pathways in pathomechanism aging women. 2022. 6th International USERN (Universal Scientific Education and Research Network). Istanbul, Turkey.


POSTERS



  1. Navid Abedpoor,
    Kamran Ghaedi, Mohammad Hossein Nasr Esfahani. PPARγ/Pgc-1α-Fndc5 pathway up-regulation in Gastrocnemius and Heart muscle of exercised, branched chain amino acid diet fed mice. 2nd International Conference on Gastroenterology and Digestive Disorders.

    1. Fatemeh Hajibabaie, Farzaneh Taghian, Navid Abedpoor. Reversing molecular signaling pathways involved in Alzheimer's disease pathogenesis via high physical activity in old age. 2022. 6th International USERN (Universal Scientific Education and Research Network). Istanbul, Turkey.


PATENT



  1. Mouse Models of Type 2 Diabetes Mellitus due to AGEs and sedentary.
     Patent no. 139750140003010609

MY PROJECTS



  1. Effects of branched-chain amino acid supplement associated with aerobic training on plasma irisin and gastrocnemius and heart muscle Fndc5 expression in male C57BL/6 mice.
  2. Create Mice models of type 2 diabetes.
  3. Designed diets (High fat diet 45 & 60%, Advanced glycation end products, enrich antioxidant and omega 3).
  4. Assessment of genes expression in energy expenditure axis upon a high-fat diet enriched with advanced glycation end products.
  5. Analysis Transcriptomics of diabetic and pre-diabetic mice.
  6. Effects of herbal drugs and endurance exercise in mitochondrial functional and oxidative pathway in muscle of T2DM mice models.

    1. Assessment of genes expression in energy expenditure axis and metabolism upon a high fat diet enriched with advanced glycation end products.
    2. Anti-inflammatory effect of phytoarthrit on DSS-induced colitis mice model challenged with High Fat Diet enriched with advanced glycation end products.
    3. Cross Talk between Gut and brain in depression condition



GRANT



  1. Elite Researcher, National Institute for Medical Research Development (NIMAD). 2016, Investigating the effects of the novel combination of several herbal extracts and exercise training on expression of gene profile involved in mitochondrial function and biogenesis in high fat diet C57BL/6 mice as a diabetic model.
  2. Elite Researcher, National Institute for Medical Research Development (NIMAD). 2018, Assessment of genes expression in energy expenditure axis upon a high-fat diet enriched with advanced glycation end products.
  3. Elite Researcher, National Institute for Medical Research Development (NIMAD). 2019,
    Analysis Transcriptomics of diabetic and pre-diabetic mice.

HONOR


Won the Young Scientist Award in “International Scientist Awards on Engineering, Science, and Medicine.” 2020



CONFERENCEAWARDS


17th International Conference on Nutrition and Fitness, video presentation, 2019, Vienna, Austria.



LABORATORY
SKILLS



  1. Bioinformatics:


  1. Primer designing (Oligo, Beacon designer, Primer3, Quik Change Primer Design, Primer X)
  2. Gene bank databases (NCBI, Ensemble, UCSC)
  3. Protein-Protein intraction analysis
  4. Cytoscape
  5. Gephi analysis


  1. Artificial intelligence in biology and health science



  1. Molecular techniques:


  1. PCR reverse transcriptase PCR, Real Time PCR
  2. Gel Electrophoresis
  3. Western blotting



  1. Cell culture techniques


  1. Immortal cells culture (adherent and suspension)
  2. Fibroblast cells culture
  3. Stem Cells culture and their differentiation.
  4. Cell and Tissue Staining



  1. Animal working:

    1. Oral Gavage
    2. Injected (Subcutaneous, Intraperitoneal, intradermal, Intramuscular, Intravenous)
    3. Blood collection (Lateral Tail Vein, Saphenous vein, Intravenous Injections)
    4. Surgery
    5. Handling and Restraint
    6. Euthanasia
    7. Animal cell culture




Knowledge



  1. Prism software
  2. SPSS
  3. Microsoft Office
  4. Presentation Software
  5. Image J
  6. Adobe Photoshop


CoachingLevel



  1. Karate                                                                                                                          Third Class
  2. Bodybuilding                                                                                                      Third Class
  3. Fitness                                                                                                                         Third Class







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