Shirin Varmazyar
Shirin Varmazyar, MD
Tehran, Iran | Mobile: (+98) 912-8691926 | [email protected] | LinkedIn
Professional Summary
● General practitioner with strong interpersonal skills in research.
● Use of Lab animals in research cell culture and histology (case study on Rats).
● Conduct through research including sample runs, data analysis using SPSS, and troubleshooting.
● Research Interests: Internal medicine, dermatology, cancer research, radiology.
Education
02/13-04/20
07/20-07/22
Hands-on experience dealing with patient diagnosed with Covid-19, provided healthcare and preventive actions based on the WHO guidelines.
Provided high-quality patient care in a hospital setting while balancing academic responsibilities.
Detail-oriented in checking patients' symptoms, ordering lab tests and on-point treatment plans.
Shahroud Azad University of Medical Sciences, Semnan, Iran
Doctor of Medicine, MD, General Practitioner
Thesis Topic: “Investigation of the Effects of Methylphenidate and Endurance Exercise on Structural Changes in Brain Tissue of Male Rats with Hyperactivity”, Supervisor: Dr. Behrooz Yahyaei
Work Experience
Sina hospital, M.S Disease Research Center, Tehran University of Medical Sciences, Iran 09/22-Now Monitoring of disease modifying drugs in patients with multiple sclerosis beyond 2 years
(a cross sectional study).
Family Medicine Physician, Charbagh Clinic, Alborz University of Medical Sciences, Iran
Research Experience
Shahroud Azad University of Medical Sciences, Iran
05/22-Now
03/22-Now
Gastric polyposis due to PPI administration (A case report):
A case report that a 57-years old man with history of PPI using for many years did endoscopy and the pathology changes were compatible with gastric polyp. Histological findings could show the relation between anti acid therapy and gastric polyp in our patient (Under review).
Animal lab (obese male rats) case study:
Investigating the effect of aerobic training along with garlic and Stevia Rebaudiana extract on the alteration of liver tissue and lipid profile of obese male rats (Under review).
01/21-02/22
05/20-06/21
Gastric Cancer Treatment:
Implications for Cytotoxicity, Gene Expression and Anti-Cancer Studies in Gastric Cancer Cell Line, by using the Scenedesmus obliquus extract, in order to investigate anticancer potential of PtFe2O4@Ag NPs. It was found that gastric cancer cells and elucidated the molecular mechanism of their cytotoxicity potential via triggering the apoptotic pathway.
Clinical study of attention deficit hyperactivity disorder (ADHD) on male Wistar rats:
Compare effects of Methylphenidate and endurance exercise on histopathological changes in brain tissue. The effect of exercise alone to methylphenidate is greater on brain tissue changes. Although the drug has been more effective on improving some variables such as changes in gray matter, it has not reduced neuronal changes, congestion and inflammation not seen in the exercise group. Also, the study results of simultaneous drug use and exercise are satisfactory.
Publications
1. Fani, A., Varmazyar, S., Akbari, F., Garfami, M., Mohaghegh, R., Balkhi, S., Mojdehi, S.R., Tabassi,
N.R., Hosseinpour, T., Ghanbari, Z. and Salehzadeh, A., 2022. Green Synthesis of a Novel PtFe2O4@ Ag Nanocomposite: Implications for Cytotoxicity, Gene Expression and Anti-Cancer Studies in Gastric Cancer Cell Line. Journal of Cluster Science, pp.1-12.
2. Yahyaei, B. and Varmazyar, S., 2021. Investigation of the Effects of Methylphenidate and Endurance Exercise on Structural Changes in Brain Tissue of Male Rats with Hyperactivity. Jorjani Biomedicine Journal, 9(2), pp.45-54.
3. Yahyaei, B. and Varmazyar, S., Evaluation of the aerobic exercise effect along garlic and Stevia Rebaudiana extract on the kidney and testis tissue changes of obese male rats. (Under Review)
4. Razavianzadeh N, Varmazyar S., Gastric Polyposis (Under Review)
due to PPI administration: A case report.
Meta-analysis
Office Suite (Power Point, Word, Excel) Scientific Writing
Polymerase Chain Reaction (PCR) and Electrophoresis
Weternblot
Computer Skills
● Data Analysis using SPSS ● EndNote
● General computer skills
Lab Skills
● Research work on lab animal (mice and rate)
● Histology & Cell Culture
● ● ●
● ●
Professional Certificates and Workshops
● Scientific Writing, Systematic Review, Meta-Analysis, SPSS, End Note, USERN Summer Workshop, Tehran University of Medical Sciences (TUMS), Aug. 2022.
2
● Introduction to Use of Lab Animals in Biotech. Research, Cell Culture, Histology, Male and Female Experimental Embryology in mouse and Introduction to Lab Equipment, 50-hour workshop, Tehran, Iran, July-Aug. 2022.
● Polymerase Chain Reaction (PCR) and Electrophoresis Contents: Sample Runs, Data Analysis, and Troubleshooting, Nama Bio-Gene Institute, Tehran University of Medical Sciences, Tehran, Iran, July 2022.
● Polymerase Chain Reaction (PCR) and Electrophoresis, 2-days workshop, TUMS.
Honors and Membership
● Among top 0.25% in nationwide entrance examination to B.Sc. program - medical school in Iran, 2013.
● Member of Tehran IRI Medical Council, Alborz, Iran, 2020-present.
Language Proficiency
● Persian: Native
● English: Professional Proficiency
References
● Dr. Behrooz Yahyaei, Shahroud Azad University of Medical Sciences, Semnan, Iran
[email protected]
● Nasrin Razavianzadeh, Shahroud Azad University of Medical Sciences, Semnan, Iran
[email protected]
● Dr. Ali Salehzadeh, Islamic Azad University, Rasht, Iran
[email protected]
3
Tehran, Iran | Mobile: (+98) 912-8691926 | [email protected] | LinkedIn
Professional Summary
● General practitioner with strong interpersonal skills in research.
● Use of Lab animals in research cell culture and histology (case study on Rats).
● Conduct through research including sample runs, data analysis using SPSS, and troubleshooting.
● Research Interests: Internal medicine, dermatology, cancer research, radiology.
Education
02/13-04/20
07/20-07/22
Hands-on experience dealing with patient diagnosed with Covid-19, provided healthcare and preventive actions based on the WHO guidelines.
Provided high-quality patient care in a hospital setting while balancing academic responsibilities.
Detail-oriented in checking patients' symptoms, ordering lab tests and on-point treatment plans.
Shahroud Azad University of Medical Sciences, Semnan, Iran
Doctor of Medicine, MD, General Practitioner
Thesis Topic: “Investigation of the Effects of Methylphenidate and Endurance Exercise on Structural Changes in Brain Tissue of Male Rats with Hyperactivity”, Supervisor: Dr. Behrooz Yahyaei
Work Experience
Sina hospital, M.S Disease Research Center, Tehran University of Medical Sciences, Iran 09/22-Now Monitoring of disease modifying drugs in patients with multiple sclerosis beyond 2 years
(a cross sectional study).
Family Medicine Physician, Charbagh Clinic, Alborz University of Medical Sciences, Iran
Research Experience
Shahroud Azad University of Medical Sciences, Iran
05/22-Now
03/22-Now
Gastric polyposis due to PPI administration (A case report):
A case report that a 57-years old man with history of PPI using for many years did endoscopy and the pathology changes were compatible with gastric polyp. Histological findings could show the relation between anti acid therapy and gastric polyp in our patient (Under review).
Animal lab (obese male rats) case study:
Investigating the effect of aerobic training along with garlic and Stevia Rebaudiana extract on the alteration of liver tissue and lipid profile of obese male rats (Under review).
01/21-02/22
05/20-06/21
Gastric Cancer Treatment:
Implications for Cytotoxicity, Gene Expression and Anti-Cancer Studies in Gastric Cancer Cell Line, by using the Scenedesmus obliquus extract, in order to investigate anticancer potential of PtFe2O4@Ag NPs. It was found that gastric cancer cells and elucidated the molecular mechanism of their cytotoxicity potential via triggering the apoptotic pathway.
Clinical study of attention deficit hyperactivity disorder (ADHD) on male Wistar rats:
Compare effects of Methylphenidate and endurance exercise on histopathological changes in brain tissue. The effect of exercise alone to methylphenidate is greater on brain tissue changes. Although the drug has been more effective on improving some variables such as changes in gray matter, it has not reduced neuronal changes, congestion and inflammation not seen in the exercise group. Also, the study results of simultaneous drug use and exercise are satisfactory.
Publications
1. Fani, A., Varmazyar, S., Akbari, F., Garfami, M., Mohaghegh, R., Balkhi, S., Mojdehi, S.R., Tabassi,
N.R., Hosseinpour, T., Ghanbari, Z. and Salehzadeh, A., 2022. Green Synthesis of a Novel PtFe2O4@ Ag Nanocomposite: Implications for Cytotoxicity, Gene Expression and Anti-Cancer Studies in Gastric Cancer Cell Line. Journal of Cluster Science, pp.1-12.
2. Yahyaei, B. and Varmazyar, S., 2021. Investigation of the Effects of Methylphenidate and Endurance Exercise on Structural Changes in Brain Tissue of Male Rats with Hyperactivity. Jorjani Biomedicine Journal, 9(2), pp.45-54.
3. Yahyaei, B. and Varmazyar, S., Evaluation of the aerobic exercise effect along garlic and Stevia Rebaudiana extract on the kidney and testis tissue changes of obese male rats. (Under Review)
4. Razavianzadeh N, Varmazyar S., Gastric Polyposis (Under Review)
due to PPI administration: A case report.
Meta-analysis
Office Suite (Power Point, Word, Excel) Scientific Writing
Polymerase Chain Reaction (PCR) and Electrophoresis
Weternblot
Computer Skills
● Data Analysis using SPSS ● EndNote
● General computer skills
Lab Skills
● Research work on lab animal (mice and rate)
● Histology & Cell Culture
● ● ●
● ●
Professional Certificates and Workshops
● Scientific Writing, Systematic Review, Meta-Analysis, SPSS, End Note, USERN Summer Workshop, Tehran University of Medical Sciences (TUMS), Aug. 2022.
2
● Introduction to Use of Lab Animals in Biotech. Research, Cell Culture, Histology, Male and Female Experimental Embryology in mouse and Introduction to Lab Equipment, 50-hour workshop, Tehran, Iran, July-Aug. 2022.
● Polymerase Chain Reaction (PCR) and Electrophoresis Contents: Sample Runs, Data Analysis, and Troubleshooting, Nama Bio-Gene Institute, Tehran University of Medical Sciences, Tehran, Iran, July 2022.
● Polymerase Chain Reaction (PCR) and Electrophoresis, 2-days workshop, TUMS.
Honors and Membership
● Among top 0.25% in nationwide entrance examination to B.Sc. program - medical school in Iran, 2013.
● Member of Tehran IRI Medical Council, Alborz, Iran, 2020-present.
Language Proficiency
● Persian: Native
● English: Professional Proficiency
References
● Dr. Behrooz Yahyaei, Shahroud Azad University of Medical Sciences, Semnan, Iran
[email protected]
● Nasrin Razavianzadeh, Shahroud Azad University of Medical Sciences, Semnan, Iran
[email protected]
● Dr. Ali Salehzadeh, Islamic Azad University, Rasht, Iran
[email protected]
3
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